Capecitabine CAS 154361-50-9 Mimọ 98.0% ~ 102.0% API Didara Giga
Ipese Iṣowo Capecitabine Awọn agbedemeji ibatan:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9
| Orukọ Kemikali | Capecitabine |
| Nọmba CAS | 154361-50-9 |
| NỌMBA CAT | RF-API08 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C15H22FN3O6 |
| Òṣuwọn Molikula | 359.35 |
| Ojuami Iyo | 110.0 ~ 121.0 ℃ |
| Sowo Ipò | Labẹ Ibaramu otutu |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun Powder |
| Idanimọ | Apeere IR Spectrum yẹ ki o ni ibamu pẹlu irisi ti boṣewa itọkasi |
| Idanimọ | HPLC: Akoko idaduro ti tente oke pataki ti ojutu ayẹwo yẹ ki o baamu ti boṣewa itọkasi. |
| Mimo | 98.0% ~ 102.0% (lori ipilẹ anhydrous ati ti ko ni epo) |
| Yiyi opitika | +96.0°~+100° |
| Ọrinrin (KF) | ≤0.30% |
| Aloku lori iginisonu | ≤0.10% |
| Awọn irin Heavy | ≤20ppm |
| Ti o jọmọ aimọ A | ≤0.30% |
| Jẹmọ aimọ B | ≤0.30% |
| Jẹmọ aimọ C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
| Nikan Aisọye Aimọ | ≤0.10% |
| Lapapọ Awọn aimọ ti a ko ni pato | ≤0.50% |
| Lapapọ Awọn Aimọ | ≤1.5% |
| Awọn ojutu ti o ku (GC) | |
| kẹmika kẹmika | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl acetate | ≤5000ppm |
| Toluene | ≤800ppm |
| Pyridine | ≤200ppm |
| Hexane | ≤290ppm |
| Lapapọ Aerobic makirobia kika | ≤200cfc/g |
| Iwukara ati Molds Ka | ≤50cfc/g |
| Igbeyewo Standard | Orilẹ Amẹrika Pharmacopoeia (USP) |
| Lilo | Metastatic Breast Cancer |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Capecitabine (CAS: 154361-50-9) jẹ fọọmu tuntun ti oogun pyrimidine fluorinated oral.Capecitabine jẹ idagbasoke nipasẹ Roche Pharmaceuticals, ati pe orukọ iṣowo rẹ jẹ Xeloda.Capecitabine le yipada ni vivo sinu 5-FU, anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate oogun ti o fojusi awọn sẹẹli alakan lati dena pipin sẹẹli ati ki o fa RNA ati iṣelọpọ amuaradagba.Awọn ipa rẹ ni pataki ti so pọ si ipele ti ikosile enzymu TP ni tissu neoplastic ati si DPD enzymu ni ikosile vivo.O dara bi itọju siwaju sii fun awọn alaisan alakan igbaya akọkọ tabi metastatic ti ko dahun si paclitaxel tabi awọn egboogi anthracycline.Gẹgẹbi oogun anticancer, o jẹ pupọ julọ lati ṣe itọju alakan igbaya akọkọ ti ilọsiwaju tabi metastatic, bakannaa ni itọju fun akàn ẹdọfóró sẹẹli ti kii ṣe kekere, akàn pancreatic, akàn àpòòtọ, akàn rectal, akàn ọfun, akàn inu, ati awọn èèmọ to lagbara miiran. .
