Carvedilol Phosphate Hemihydrate CAS 610309-89-2 Mimọ>99.0% (HPLC)
Shanghai Ruifu Kemikali Co., Ltd jẹ olupese ti Carvedilol Phosphate Hemihydrate (CAS: 610309-89-2) pẹlu didara to gaju.Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati titobi nla ti o wa.Ra Carvedilol Phosphate Hemihydrate,Please contact: alvin@ruifuchem.com
Jẹmọ Intermediates ti Carvedilol
Orukọ Kemikali | Carvedilol Phosphate Hemihydrate |
Awọn itumọ ọrọ sisọ | BM 14190 Phosphate Hemihydrate;1- (9H-Carbazol-4-yloxy) -3-[2- (2-Methoxyphenoxy) ethylamino] propan-2-olphosphoricacidhydrate. |
Iṣura Ipo | O wa |
Nọmba CAS | 610309-89-2 |
Fọọmu Molecular | C24H26N2O4.H3PO4.0.5H2O |
Òṣuwọn Molikula | 513,47 g / mol |
COA & MSDS | Wa |
Brand | Ruifu Kemikali |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | Funfun Crystalline Powder | Ibamu |
Omi nipa Karl Fischer | ≤2.50% | Ibamu |
Awọn nkan ti o jọmọ | ≤0.50% | Ibamu |
Awọn Irin Eru (Pb) | ≤10ppm | <10ppm |
Mimọ / Analysis Ọna | > 99.0% (HPLC) | 99.5% |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto | Ibamu |
Ipari | Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Tọju ni wiwọ titi eiyan.Fipamọ sinu itura, gbigbẹ (2 ~ 8℃) ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Carvedilol Phosphate Hemihydrate (CAS: 610309-89-2) jẹ yiyan didi α1-receptor ati ti kii ṣe yiyan β-receptor blocker, ko si awọn oogun ti nṣiṣe lọwọ inu inu, bioavailability ti 10 ~ 47%, ko ni ipa nipasẹ ounjẹ, ipa lori α1 -receptor is significantly less than β1-ati β2-receptor, awọn kikankikan ipin ti β 1-ati β 2-receptor blockade jẹ 1:10 ~ 1:100.Ipa ti blockade β 1-receptor jẹ nipa 1/2 ti labetalol, ati idena α1 rẹ jẹ alailagbara ju prazosin lọ.O le dilate awọn ohun elo ẹjẹ, dinku resistance ti iṣan agbeegbe, dilate iṣọn-alọ ọkan ati awọn ohun elo kidirin, ati dinku titẹ titẹ ẹdọforo.O ni ipa aabo ti o han gbangba lori hypoxia myocardial ati ipalara myocardial ti o fa nipasẹ infarction myocardial, eyiti o le ni ibatan si didi β-receptor, eyiti o le dinku idinku ti glycogen myocardial ati ilosoke pH, ati dinku iwọn infarct.
Carvedilol Phosphate Hemihydrate ni a lo lati tọju haipatensonu kekere si iwọntunwọnsi ati pe o le ṣee lo nikan tabi ni apapo pẹlu awọn oogun antihypertensive miiran (paapaa diuretics thiazide).Fun symptomatic onibaje congestive ikuna okan.
Carvedilol Phosphate Hemihydrate jẹ blocker β/α-1 ti kii ṣe yiyan.Carvedilol ṣe idiwọ peroxidation ọra pẹlu IC50 ti 5 μM.Carvedilol jẹ aṣoju antihypertensive pupọ-idi pẹlu agbara fun iwadi ti angina pectoris ati ikuna ọkan iṣọn-alọ ọkan.