Posaconazole Intermediate CAS 175712-02-4 Mimọ> 99.0% (GC) Factory
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti Posaconazole Intermediate (CAS: 175712-02-4) pẹlu didara to gaju.Ruifu Kemikali n pese lẹsẹsẹ ti awọn agbedemeji elegbogi.Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, kekere ati awọn iwọn olopobobo ti o wa.Ra Agbedemeji Posaconazole,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | Posaconazole Intermediate |
Awọn itumọ ọrọ sisọ | Posaconazole Aimọ 21;(5R-Cis) - P-Chlorobenzenesulfonic Acid 5;[(3S, 5R) -5- (2,4-Difluorophenyl) -5- (1,2,4-triazol-1-ylmethyl) tetrahydrofuran-3-yl] methyl 4-Chlorobenzenesulfonate;(3S-cis) -4-Chlorobenzenesulfonic Acid [5- (2,4-Difluorophenyl) tetrahydro-5- (1H-1,2,4-triazol-1-ylmethyl) -3-Furanyl] methyl Ester |
Iṣura Ipo | O wa |
Nọmba CAS | 175712-02-4 |
Fọọmu Molecular | C20H18ClF2N3O4S |
Òṣuwọn Molikula | 469,89 g / mol |
iwuwo | 1,49 ± 0,10 g / cm3 |
Ibi ipamọ otutu. | Itura & Ibi Gbẹ (2 ~ 8℃) |
COA & MSDS | Wa |
Ẹka | elegbogi Intermediates |
Brand | Ruifu Kemikali |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | White Ri to | White Ri to |
Omi nipa Karl Fischer | <0.50% | 0.20% |
Mimọ / Analysis Ọna | > 99.0% (GC) | 99.3% |
1 H NMR julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
LCMS | Ni ibamu pẹlu Eto | Ibamu |
Ipari | Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti o ni edidi ni itura ati ile-itọju gbigbẹ kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Posaconazole Intermediate (CAS: 175712-02-4) jẹ agbedemeji ti Posaconazole (CAS: 171228-49-2).Posaconazole, ti a ṣe ifilọlẹ ni UK, jẹ ọmọ ẹgbẹ tuntun ti kilasi azole ti awọn aṣoju antifungal lati de ọja naa.O jẹ itọkasi fun itọju ati prophylaxis ti ọpọlọpọ awọn akoran olu ifarapa, pẹlu aspergillosis, fusariosis, chromoblastomycosis, mycetoma, ati coccidiomycosis ninu awọn alaisan ti o ni itara si, tabi alailagbara, itọju boṣewa pẹlu amphotericin B ati/tabi itraconazole.Ni AMẸRIKA, o fọwọsi fun prophylaxis ti Aspergillus invasive ati awọn akoran Candida ninu awọn alaisan ti o jẹ ọmọ ọdun 13 ti o wa ninu eewu giga ti idagbasoke awọn akoran wọnyi nitori jijẹ ajẹsara to lagbara.Ni afikun, o jẹ ifọwọsi fun itọju ti oropharyngeal candidiasis.Posaconazole ni iṣẹ ṣiṣe ti o gbooro sii lori awọn ọmọ ẹgbẹ miiran ti azole antifungals.Ni afikun si iṣẹ ṣiṣe ti o lagbara lodi si awọn ọran aspergillosis ati fluconazole-sooro Candida, o ṣe afihan iṣẹ ṣiṣe lodi si Zygomycetes.
Biochem/Physiol Actions Posaconazole jẹ aṣoju antifungal broadspectrum ti o lagbara pupọ si ikolu iwukara ti o ṣẹlẹ paapaa nipasẹ Candida sp.O ṣe idiwọ idagba ti elu nipa didi enzyme lanosterol 14a-demethylase (CYP51).Ni idakeji si awọn azoles antifungal miiran, a ti royin posaconazole lati ma fa ẹrọ fifajade efflux.Posaconazole ṣe afihan awọn ipa antichagasic lodi si awọn igara ti Trypanosoma cruzi ti o nfa arun Chagas.
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