CAS 177036-94-1 Mimo>99.0% (HPLC) Aworan Ififihan Mimo giga ti API

CAS 177036-94-1 Mimo>99.0% (HPLC) API Iwa mimọ giga Factory

Apejuwe kukuru:

CAS: 177036-94-1

Mimọ:> 99.0% (HPLC)

Irisi: Funfun tabi Paa-White Powder

Itoju Haipatensonu iṣan Ẹdọforo (PAH)

API Didara Giga, Iṣelọpọ Iṣowo

E-Mail: alvin@ruifuchem.com

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Apejuwe:

Ipese Iṣowo (CAS: 177036-94-1) Awọn agbedemeji ti o jọmọ:
CAS: 177036-94-1
Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3
2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9
(S) -2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0
L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6
4,6-Dimethyl-2- (Methylsulfonyl) pyrimidine CAS: 35144-22-0

Kemikali Properties:

Orukọ Kemikali	(S) -2-[(4,6-Dimethylpyrimidin-2-yl) oxy] -3-Methoxy-3,3-Diphenylpropionic Acid
Awọn itumọ ọrọ sisọ	(+-) (2S) -2- ((4,6-Dimethylpyrimidin-2-yl) oxy) -3-Methoxy-3,3-Diphenylpropanoic Acid
Nọmba CAS	177036-94-1
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Fọọmu Molecular	C22H22N2O4
Òṣuwọn Molikula	378.43
Yiyi pato [α] D20	+170.0° si +176.0° (C=0.5, MeOH)
Ojuami Iyo	172.0 ~ 178.0 ℃ (oṣu kejila)
Solubility	Tiotuka pupọ ni kẹmika;Soluble ni Ethanol, Acetone;Ailopin ninu Omi
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun tabi Pa-White Powder
Idanimọ	HPLC;NMR;LC-MS
Awọn nkan ti o jọmọ
Olukuluku Aimọ	≤0.50%
Lapapọ Awọn Aimọ	<1.00%
Pipadanu lori Gbigbe	≤0.50%
Aloku lori Iginisonu	≤0.20%
Awọn irin Heavy	≤20ppm
Mimọ / Analysis Ọna	> 99.0% (HPLC)
Igbeyewo Standard	Standard Enterprise
Lilo	elegbogi Intermediates

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

FAQ:

Ohun elo:

(CAS: 177036-94-1) APIjẹ antagonist olugba endothelin-A (ETA) ti o yan ti a ṣe fun itọju ẹnu ti awọn alaisan ti o ni haipatensonu iṣọn-ẹjẹ ti ẹdọforo (PAH), lati mu agbara idaraya dara ati idaduro buru si ile-iwosan.PAH jẹ aisan ti o ṣọwọn ti awọn iṣọn-ẹjẹ kekere ti iṣan ti iṣan ti iṣan ti iṣan ti iṣan ati atunṣe, ti o mu ki ilọsiwaju ti o ni ilọsiwaju ti iṣan ti iṣan ẹdọforo ati titẹ iṣan ẹdọforo, ati nikẹhin, ikuna ventricular ọtun ati iku ti o tọ.Awọn aami aisan ibẹrẹ ti PAH pẹlu ibẹrẹ mimu ti kukuru ti ẹmi, rirẹ, palpitation, edema, ati daku.Endothelin-1 (ET-1), vasoconstrictor ti o lagbara ati mitogen iṣan dan, jẹ oluranlọwọ bọtini si isare ti arun na, ati pe awọn ipa rẹ jẹ ilaja nipasẹ ṣiṣiṣẹ tiETA ati awọn olugba ETB.Ni Oṣu Kẹfa ti ọdun 2007, FDA funni ni ifọwọsi (CAS: 177036-94-1) API fun itọju lẹẹkan lojoojumọ ti PAH.