Gefitinib Intermediate CAS 199327-61-2 Mimọ>99.0% (HPLC)
Shanghai Ruifu Kemikali Co., Ltd jẹ olupese ti 7-Methoxy-6- (3-Morpholin-4-ylpropoxy) quinazolin-4 (3H) - Ọkan (CAS: 199327-61-2) pẹlu didara to gaju, agbedemeji. ti Gefitinib (CAS: 184475-35-2).Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra Gefitinib Intermediates,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | 7-Methoxy-6- (3-Morpholin-4-ylpropoxy) quinazolin-4(3H) -Ọkan |
| Awọn itumọ ọrọ sisọ | 7-Methoxy-6- (3-Morpholinopropoxy) quinazolin-4 (3H) - Ọkan;7-Methoxy-6- [3- (4-Morpholinyl) aṣoju] -4 (3H) - Quinazolinone;7-Methoxy-6- (3-Morpholinopropoxy) quinazolin-4-Ọkan |
| aimọ | Gefitinib aimọ 5;Gefitinib EP aimọ A |
| Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
| Nọmba CAS | 199327-61-2 |
| Fọọmu Molecular | C16H21N3O4 |
| Òṣuwọn Molikula | 319,36 g / mol |
| Ojuami Iyo | 242.0 ~ 247.0 ℃ |
| iwuwo | 1,32 ± 0,10 g / cm3 |
| COA & MSDS | Wa |
| Ipilẹṣẹ | Shanghai, China |
| Brand | Ruifu Kemikali |
| Awọn nkan | Ayewo Standards | Esi |
| Ifarahan | Funfun to Pa-White Powder | Ibamu |
| Ojuami Iyo | 242.0 ~ 247.0 ℃ | 243.6 ~ 244,5 ℃ |
| Pipadanu lori Gbigbe | <0.50% | 0.15% |
| Aloku lori Iginisonu | <0.20% | 0.11% |
| Aimọ Kanṣoṣo | <0.50% | <0.30% |
| Lapapọ Awọn Aimọ | <1.00% | 0.30% |
| Mimọ / Analysis Ọna | > 99.0% (HPLC) | 99.7% |
| 1H NMR julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
| Ipari | Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun | |
| Ohun elo | Agbedemeji ti Gefitinib (CAS: 184475-35-2) | |
Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati tọju ni itura, gbẹ (2 ~ 8℃) ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
7-Methoxy-6- (3-Morpholin-4-ylpropoxy) quinazolin-4 (3H) - Ọkan (CAS: 199327-61-2) jẹ agbedemeji / aimọ ti Gefitinib (CAS: 184475-35-2).Gefitinib jẹ oogun elegbogi ti o ni idojukọ pataki egboogi-tumor ti o dagbasoke nipasẹ AstraZeneca, UK.Gefitinib jẹ oogun ifọkansi molikula akọkọ fun itọju ti akàn ẹdọfóró sẹẹli ti kii ṣe kekere.O ṣiṣẹ nipa yiyan idinamọ ipa ọna gbigbe ifihan agbara ti epidermal idagbasoke ifosiwewe tyrosine kinase (EGFR-TK).Ni Oṣu Kẹjọ ọdun 2002, Gefitinib ti kọkọ ta ọja ni Japan bi itọju laini akọkọ fun akàn ẹdọfóró sẹẹli ti kii ṣe kekere labẹ orukọ iṣowo Iressa.Ni Oṣu Karun ọdun 2003, Ile-iṣẹ Ounje ati Oògùn AMẸRIKA fọwọsi Gefitinib gẹgẹbi monotherapy laini kẹta fun awọn alaisan ti o ni ilọsiwaju ti akàn ẹdọfóró sẹẹli ti kii-kekere ti ko ni doko pẹlu awọn oogun anticancer ti o da lori Pilatnomu ati kimoterapi docetaxel.Ni lọwọlọwọ, Gefitinib ti fọwọsi nipasẹ Australia, Japan, Argentina, Singapore ati South Korea fun itọju ti akàn ẹdọfóró ti kii-kekere sẹẹli ti ilọsiwaju.Ni Oṣu Keji ọjọ 28, Ọdun 2005, Ile-iṣẹ Ounje ati Oògùn ti Ilu China fọwọsi Gefitinib fun itọju ti ilọsiwaju ti agbegbe tabi akàn ẹdọfóró ti kii-kekere sẹẹli (NSCLC) ti o ti gba chemotherapy tẹlẹ.Ko fọwọsi lọwọlọwọ fun lilo bi itọju ailera laini akọkọ fun NSCLC ti ilọsiwaju.Ni Oṣu Keje Ọjọ 1, Ọdun 2009, Ile-iṣẹ Oogun Yuroopu fọwọsi Gefitinib ni ifowosi fun laini akọkọ, laini-keji ati itọju laini kẹta ti ilọsiwaju agbegbe tabi akàn ẹdọfóró ti kii-kekere sẹẹli pẹlu awọn iyipada jiini EGFR ninu awọn agbalagba.
