3-Chloro-4- (3-Fluorobenzyloxy) aniline CAS 202197-26-0 Lapatinib Intermediate Purity> 98.0% (HPLC)

Apejuwe kukuru:

Orukọ Kemikali: 3-Chloro-4- (3-Fluorobenzyloxy) aniline

CAS: 202197-26-0

Mimọ:> 98.0% (HPLC)

Irisi: Brown to Black Powder

Agbedemeji ti Lapatinib / Lapatinib Ditosylate Monohydrate

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Alaye ọja

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ọja Tags

Apejuwe:

Shanghai Ruifu Kemikali Co., Ltd jẹ olupese ti 3-Chloro-4- (3-Fluorobenzyloxy) aniline (CAS: 202197-26-0) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra Lapatinib Intermediates,Please contact: alvin@ruifuchem.com

Lapatinib Intermediates:

Kemikali Properties:

Orukọ Kemikali 3-Chloro-4- (3-Fluorobenzyloxy) aniline
Awọn itumọ ọrọ sisọ 3-Chloro-4- [(3-Fluorophenyl) methoxy] aniline;4- (3-Fluorobenzyloxy) -3-Chlorobenzenamine;Lapatinib Intermediate B
Iṣura Ipo Ni Iṣura, Iṣowo Iṣowo
Nọmba CAS 202197-26-0
Fọọmu Molecular C13H11ClFNO
Òṣuwọn Molikula 251,69 g / mol
Ojuami Iyo 78.0 si 82.0 ℃
iwuwo 1.306 ± 0,06 g / cm3
COA & MSDS Wa
Apeere Wa
Ipilẹṣẹ Shanghai, China
Brand Ruifu Kemikali

Awọn pato:

Awọn nkan Ayewo Standards Esi
Ifarahan Brown to Black Powder Ibamu
Ojuami Iyo 78.0 si 82.0 ℃ 80.7 ℃
Pipadanu lori Gbigbe <1.00% Ibamu
Aloku lori Iginisonu <0.50% Ibamu
Jẹmọ impurities nipa HPLC <2.00% 0.64%
Mimọ / Analysis Ọna > 98.0% (HPLC) 99.36%
1H NMR julọ.Oniranran Ni ibamu pẹlu Eto Ibamu
Ipari Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun
Ohun elo Agbedemeji ti Lapatinib / Lapatinib Ditosylate Monohydrate

Package/Ipamọ/Gbigbe:

Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.

Awọn anfani:

Agbara to to: Awọn ohun elo to ati awọn onimọ-ẹrọ

Iṣẹ Ọjọgbọn: Iṣẹ rira iduro kan

OEM Package: Aṣa package ati aami wa

Ifijiṣẹ Yara: Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta

Ipese Idurosinsin: Ṣetọju ọja iṣura ti o tọ

Atilẹyin imọ-ẹrọ: Ojutu imọ-ẹrọ wa

Iṣẹ Iṣọkan Aṣa: Larin lati giramu si kilos

Didara to gaju: Ṣeto eto idaniloju didara pipe

FAQ:

Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere ​​kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.

202197-26-0 - Alaye aabo:

UN ID 3077
HS koodu 2921420090
Ewu Kilasi 9
Iṣakojọpọ Ẹgbẹ III

202197-26-0 - Ohun elo:

3-Chloro-4- (3-Fluorobenzyloxy) aniline (CAS: 202197-26-0) jẹ agbedemeji ninu iṣelọpọ ti Lapatinib / Lapatinib Ditosylate Monohydrate.
Lapatinib jẹ oogun ti o fojusi akàn igbaya ti o ni idagbasoke nipasẹ Ilu Gẹẹsi GlaxoSmithKline Co. Awọn olugba ErbB Human ErbB jẹ ti idile olugba I tyrosine kinase (TK), pẹlu ErbB1 (EGFR), ErbB2 (HER2), ErbB3 (HER3), ati ErbB4 (HER4) .Awọn olugba ErbB-1 (EGFR) ati ErbB-2 (HER-2) jẹ igbagbogbo pupọju tabi bibẹẹkọ yipada ninu awọn alaisan alakan.Olugba ifosiwewe idagba eniyan epidermal 2 (ErbB-2, HER-2) ni a mọ lati jẹ onkogene eniyan ti o ni ibatan pẹkipẹki pẹlu alakan igbaya.Ikosile giga rẹ ni akàn igbaya nigbagbogbo n sọ asọtẹlẹ metastasis apa iho-ara ati iyatọ tumo ti ko dara, pẹlu asọtẹlẹ ti ko dara.HER-2 jẹ ọkan ninu awọn moleku ibi-afẹde fun itọju ailera kan-akàn igbaya.Lapatinib le ṣiṣẹ ni nigbakannaa lori mejeeji Her-1 Her-2.Awọn ipa ti ibi-ara ti ọna yii ti o dẹkun ilọsiwaju ati idagbasoke ti awọn sẹẹli tumo jẹ tobi pupọ ju ṣiṣe nikan ni ibi-afẹde kan.Apapo Lapatinib pẹlu Capecitabine ni a lo lati ṣe itọju awọn alaisan ti o ni ilọsiwaju tabi aarun igbaya igbaya metastatic ti o pọju ti olugba eniyan epidermal receptor2, ti a ti tọju tẹlẹ pẹlu anthracyclines, paclitaxel, ati trastuzumab.Awọn idanwo ile-iwosan ti fihan pe Lapatinib tun ṣe itọju awọn alaisan akàn iru HER2 pẹlu imunadoko Herceptin.

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