Lapatinib Intermediate CAS 231278-84-5 Mimọ>98.0% (HPLC)
Orukọ Kemikali | 5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde |
Awọn itumọ ọrọ sisọ | Lapatinib Intermediate 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl) methoxy] phenyl] amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5- [4- ((3-Chloro-4-- (3-Fluorobenzyl) oxy) phenyl) amino) quinazolin-6-yl] -2-Furaldehyde |
Nọmba CAS | 231278-84-5 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C26H17ClFN3O3 |
Òṣuwọn Molikula | 473.90 |
Ojuami Iyo | 225.0 si 235.0 ℃ |
iwuwo | 1,407 ± 0,06 g / cm3 |
Atọka Refractive | 1.694 |
COA & MSDS | Wa |
Ipilẹṣẹ | Shanghai, China |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Bia Yellow to Yellow ri to Powder |
Mimọ / Analysis Ọna | > 98.0% (HPLC) |
Ojuami Iyo | 225.0 ~ 235.0 ℃ |
Pipadanu lori Gbigbe | <1.00% |
Aloku lori Iginisonu | <0.50% |
Lapapọ Awọn Aimọ | <2.00% |
Awọn irin Heavy (gẹgẹbi Pb) | <20ppm |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji API (CAS 388082-77-7) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) jẹ agbedemeji API (CAS 388082-77-7) ).(CAS 388082-77-7) jẹ oogun ti o fojusi aarun igbaya igbaya ti o ni idagbasoke nipasẹ British GlaxoSmithKline Co. O jẹ inhibitor tyrosine kinase eyiti o le ṣe idiwọ iṣẹ ṣiṣe tyrosine kinase daradara ti awọn olugba idagbasoke ifosiwewe epidermal eniyan 1 ati 2 (ErbB1, ErbB2).O le ṣe iyasọtọ ni awọn ọna oriṣiriṣi, ni idaniloju pe awọn sẹẹli alakan igbaya ko le gba awọn ifihan agbara idagbasoke.O ṣe idiwọ EGFR intracellular intracellular (ErbB-1) ati HER2 (ErbB-2) awọn aaye ATP, idilọwọ phosphorylation sẹẹli tumo ati imuṣiṣẹ, dina awọn ifihan agbara-isalẹ nipasẹ isokan ati isokan ti EGFR (ErbB-1) ati HER2 (ErbB-1) dimerization.