Lapatinib Intermediate CAS 231278-84-5 Mimọ>98.0% (HPLC)

Apejuwe kukuru:

5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde

CAS: 231278-84-5

Mimọ:> 98.0% (HPLC)

Irisi: Bialu Yellow to Yellow Ri to Powder

Agbedemeji API (CAS 388082-77-7)

Olubasọrọ: Dokita Alvin Huang

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E-Mail: alvin@ruifuchem.com


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ọja Tags

Lapatinib Intermediates:

Kemikali Properties:

Orukọ Kemikali 5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde
Awọn itumọ ọrọ sisọ Lapatinib Intermediate 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl) methoxy] phenyl] amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5- [4- ((3-Chloro-4-- (3-Fluorobenzyl) oxy) phenyl) amino) quinazolin-6-yl] -2-Furaldehyde
Nọmba CAS 231278-84-5
Iṣura Ipo Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Ilana molikula C26H17ClFN3O3
Òṣuwọn Molikula 473.90
Ojuami Iyo 225.0 si 235.0 ℃
iwuwo 1,407 ± 0,06 g / cm3
Atọka Refractive 1.694
COA & MSDS Wa
Ipilẹṣẹ Shanghai, China
Brand Ruifu Kemikali

Awọn pato:

Nkan Awọn pato
Ifarahan Bia Yellow to Yellow ri to Powder
Mimọ / Analysis Ọna > 98.0% (HPLC)
Ojuami Iyo 225.0 ~ 235.0 ℃
Pipadanu lori Gbigbe <1.00%
Aloku lori Iginisonu <0.50%
Lapapọ Awọn Aimọ <2.00%
Awọn irin Heavy (gẹgẹbi Pb) <20ppm
Igbeyewo Standard Standard Enterprise
Lilo Agbedemeji API (CAS 388082-77-7)

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

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231278-84-5 - Ohun elo:

5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) jẹ agbedemeji API (CAS 388082-77-7) ).(CAS 388082-77-7) jẹ oogun ti o fojusi aarun igbaya igbaya ti o ni idagbasoke nipasẹ British GlaxoSmithKline Co. O jẹ inhibitor tyrosine kinase eyiti o le ṣe idiwọ iṣẹ ṣiṣe tyrosine kinase daradara ti awọn olugba idagbasoke ifosiwewe epidermal eniyan 1 ati 2 (ErbB1, ErbB2).O le ṣe iyasọtọ ni awọn ọna oriṣiriṣi, ni idaniloju pe awọn sẹẹli alakan igbaya ko le gba awọn ifihan agbara idagbasoke.O ṣe idiwọ EGFR intracellular intracellular (ErbB-1) ati HER2 (ErbB-2) awọn aaye ATP, idilọwọ phosphorylation sẹẹli tumo ati imuṣiṣẹ, dina awọn ifihan agbara-isalẹ nipasẹ isokan ati isokan ti EGFR (ErbB-1) ati HER2 (ErbB-1) dimerization.

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