1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-ọkan CAS 27387-31-1 Ondansetron HCl Dihydrate Intermediate Purity>99.0% (HPLC)

Apejuwe kukuru:

1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-ọkan

CAS: 27387-31-1

Mimọ:> 99.0% (HPLC)

Irisi: Funfun tabi Paa-White Crystalline Powder

Awọn agbedemeji ti Ondansetron Hydrochloride Dihydrate

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Jẹmọ Products

ọja Tags

Apejuwe:

Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Please contact: alvin@ruifuchem.com

Jẹmọ Intermediates:

Awọn agbedemeji ti o jọmọ ti Ondansetron Hydrochloride Dihydrate

1,3-Cyclohexanedione	CAS 504-02-9
1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-ọkan	CAS 27387-31-1
Ondansetron Hydrochloride Dihydrate	CAS 103639-04-9

Kemikali Properties:

Orukọ Kemikali	1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-ọkan
Awọn itumọ ọrọ sisọ	1,2,3,4-Tetrahydro-9-Methylcarbazol-4-ọkan;1,2,3,4-Tetrahydro-9-Methyl-4-Oxocarbazole
Iṣura Ipo	O wa
Aimọ	Ondansetron USP Jẹmọ Agbo C;Ondansetron EP Aimọ C;Ondansetron Hydrochloride Dihydrate Aimọ C
Nọmba CAS	27387-31-1
Fọọmu Molecular	C13H13NO
Òṣuwọn Molikula	199,25 g/mol
Ojuami Iyo	199.0 si 203.0 ℃
iwuwo	1,21 ± 0,10 g / cm3
COA & MSDS	Wa
Brand	Ruifu Kemikali

Awọn pato:

Awọn nkan	Ayewo Standards	Esi
Ifarahan	Funfun lati Pa-White Crystalline Powder	Ibamu
Ojuami Iyo	199.0 si 203.0 ℃	200.0 si 202.0 ℃
Aimọ Kanṣoṣo	<0.50%	Ibamu
Lapapọ Awọn Aimọ	<1.00%	Ibamu
Mimọ / Analysis Ọna	> 99.0% (HPLC)	99.65%
1 H NMR julọ.Oniranran	Ni ibamu si Eto	Ibamu
Ipari	Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato

Package/Ipamọ/Gbigbe:

Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Tọju ni wiwọ titi eiyan.Fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.

Awọn anfani:

Agbara to to: Awọn ohun elo to ati awọn onimọ-ẹrọ

Iṣẹ Ọjọgbọn: Iṣẹ rira iduro kan

OEM Package: Aṣa package ati aami wa

Ifijiṣẹ Yara: Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta

Ipese Idurosinsin: Ṣetọju ọja iṣura ti o tọ

Atilẹyin imọ-ẹrọ: Ojutu imọ-ẹrọ wa

Iṣẹ Iṣọkan Aṣa: Larin lati giramu si kilos

Didara to gaju: Ṣeto eto idaniloju didara pipe

FAQ:

Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.

Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.

Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.

DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl

Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.

Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.

MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.

Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.

Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.

Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.

Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.

Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.

27387-31-1 - Ewu ati Aabo:

Awọn koodu ewu
R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara.
R52/53 - Ipalara si awọn oganisimu omi, le fa awọn ipa buburu igba pipẹ ni agbegbe omi.
R25 - Majele ti o ba gbe
Apejuwe Abo
S22 - Maṣe simi eruku.
S24/25 - Yago fun olubasọrọ pẹlu ara ati oju.
S61 - Yago fun itusilẹ si ayika.Tọkasi awọn ilana pataki / awọn iwe data aabo.
S45 - Ni ọran ti ijamba tabi ti o ba ni ailara, wa imọran iṣoogun lẹsẹkẹsẹ (fi aami han nigbakugba ti o ṣee ṣe.)
UN ID UN 2811 6.1 / PGIII

27387-31-1 - Ohun elo:

1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) ni a lo gẹgẹbi agbedemeji Ondansetron Hydrochloride Dihydrate (CAS: 103639-04-9).Idagbasoke ile-iṣẹ United Kingdom Glaxo, 1990 ni Faranse, Ọja United Kingdom.Ọja naa jẹ olutaja olugba olugba serotonin (5-HT3) ti o yan pupọ, o le ṣe idiwọ Nausea ti o ṣẹlẹ nipasẹ chemotherapy ati Vomit radiotherapy, pẹlu agbara giga ati yiyan giga, le ṣakoso ifun kekere ati awọn olugba CTZ ti o fa nipasẹ itunra ti Vomit.O dara fun itọju eebi ríru ti o ṣẹlẹ nipasẹ chemotherapy ati radiotherapy, ati pe o tun le ṣee lo fun idena ati itọju eebi ríru ti o ṣẹlẹ lẹhin iṣẹ abẹ.

Ondansetron, granisetron ati dolasetron jẹ awọn oogun antiemetic mẹta ti a lo nigbagbogbo ni ile-iwosan, ondansetron jẹ agbara, yiyan ati iyipada 5-hydroxytryptamine (5-HT3) blocker olugba fun Alpha 1, Alpha 2, beta 1, Beta 2 adrenergic receptors ati histamine H1, olugba h2 ko ni ipa diẹ, ko si ni ipa atagonistic lori olugba H, aarin ati agbeegbe dopaminergic awọn olugba, ati pe o le ṣe idiwọ ríru ati eebi ti o ṣẹlẹ nipasẹ kimoterapi ati radiotherapy.Ti a bawe pẹlu metoclopramide, ipa antiemetic lagbara ati pe ko si esi extrapyramidal.Cisplatin, cyclophosphamide, doxorubicin ti o ṣẹlẹ nipasẹ Vomit le ṣe agbejade ipa ipakokoro-ẹgbin ni iyara ati lagbara.Dara fun itọju ti awọn oogun cytotoxic ti o fa nipasẹ chemotherapy ati itọju itanjẹ ríru Vomit, ṣugbọn idena ati itọju ti eebi ríru ti o fa nipasẹ iṣẹ abẹ.ondansetron n ṣiṣẹ bi ibudo gbigbe laarin awọn iṣan afferent visceral ti a mu ṣiṣẹ ni inu ikun ati inu ikun ati Vomit ti awọn ile-iṣẹ ninu ọpa ẹhin, nfa awọn iha inu ati diaphragmatic.Awọn oogun kimoterapi ati itọju ailera le fa itusilẹ ti 5-HT ninu ifun kekere, ati ifasilẹ Vomit jẹ eyiti o fa nipasẹ imudara ti nafu ara nipasẹ olugba 5-HT3.Ọja yii ṣe idiwọ iṣẹlẹ ti ifasilẹ yii, lakoko ti o dina eebi ti o fa nipasẹ iṣe aarin.Ilana ti iṣe jẹ aimọ fun Eebi Nausea lẹhin iṣẹ abẹ.Ondansetron ni idapo pelu dexamethasone le mu ipa antiemetic pọ si.