5- (2-Pyridyl) -1,2-Dihydropyridin-2-ọkan CAS 381233-78-9 Perampanel Intermediate Purity>98.0% (HPLC)
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ti 5- (2-Pyridyl) -1,2-Dihydropyridin-2-ọkan ([2,3'-Bipyridin] -6'(1'H) -ọkan) (CAS: 381233-78-9) pẹlu didara to gaju, agbedemeji Perampanel (CAS: 380917-97-5).Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra awọn agbedemeji Perampanel,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | 5- (2-Pyridyl) -1,2-Dihydropyridin-2-ọkan |
| Awọn itumọ ọrọ sisọ | [2,3'-Bipyridin] -6'(1'H) -ọkan;5-(Pyridin-2-yl) pyridin-2 (1H) -ọkan;5- (Pyridin-2-yl) -2 (1H) -Pyridone;5- (2-Pyridyl) pyridin-2 (1H) - ọkan;5-Pyridin-2-yl-1H-Pyridin-2-ọkan;5- (Pyridin-2-yl) -1,2-Dihydropyridin-2-ọkan;Perampanel aimọ 1 |
| Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
| Nọmba CAS | 381233-78-9 |
| Fọọmu Molecular | C10H8N2O |
| Òṣuwọn Molikula | 172,18 g / mol |
| Ojuami Iyo | 71.0 ~ 75.0 ℃ |
| iwuwo | 1,221 ± 0,06 g / cm3 |
| COA & MSDS | Wa |
| Ipilẹṣẹ | Shanghai, China |
| Ẹka | Agbedemeji ti Perampanel (CAS: 380917-97-5) |
| Igbesi aye selifu | Awọn oṣu 24 ti o ba fipamọ daradara |
| Brand | Ruifu Kemikali |
| Awọn nkan | Ayewo Standards | Esi |
| Ifarahan | Funfun to Fere White Powder | Funfun Powder |
| Mimọ / Analysis Ọna | > 98.0% (HPLC) | 99.7% |
| Omi nipa Karl Fischer | <1.00% | 0.58% |
| Aimọ Kanṣoṣo | <1.00% | Ibamu |
| Lapapọ Awọn Aimọ | <2.00% | 0.30% |
| 1H NMR julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
| Ipari | Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun | |
| Ohun elo | Agbedemeji ti Perampanel (CAS: 380917-97-5) | |
Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Awọn ohun-ini: Funfun si Fere White Powder
Solusan: Tetrahydrofuran, Toluene, Ethylacetate, Ethanol, Methanol, tert-Butyl Methyl Ether, Petroleum Ether, n-Hexane, Dichloromethane
Ṣayẹwo: Awọn nkan ti o jọmọ: Mu ọja yii ki o diluent pẹlu diluent (omi alakoso alagbeka: methanol (50∶50)) lati ṣe ojutu kan ti o ni nipa 0.5mg fun 1ml bi ojutu ọja idanwo.Gẹgẹbi kiromatografi olomi iṣẹ giga (Chinese Pharmacopoeia 2010 Edition II Afikun Ⅴ D), jeli silica (ZORBAX SB-C18 4.6 × 250mm,5m) ni a lo bi kikun.Abala alagbeka A jẹ omi, apakan alagbeka B jẹ kẹmika, ati wiwa gigun jẹ 254nm.Iwọn sisan jẹ 1.0ml/min ati iwọn otutu ọwọn jẹ iwọn otutu yara.5μl ti ojutu idanwo naa ni iwọn deede ati itasi sinu chromatograph omi lati ṣe igbasilẹ chromatogram naa.Gẹgẹbi ọna deede agbegbe, akoonu ti ọja yii ko kere ju 98%.Ti awọn oke alaimọ ba wa ninu chromatogram ti ojutu ọja idanwo, agbegbe aimọ ti ara ẹni kọọkan ko gbọdọ kọja 1.0%, ati apapọ agbegbe tente oke aimọ ko le kọja 2.0%.
Ọrinrin: Mu ọja yii, lo oluyẹwo ọrinrin, ni ibamu si ọna Karl Fischer (Chinese Pharmacopoeia 2010 edition II Appendix Ⅷ M ọna akọkọ A) ipinnu, akoonu ọrinrin ko ni kọja 1.0%.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
5- (2-Pyridyl) -1,2-Dihydropyridin-2-ọkan ([2,3'-Bipyridin] -6'(1'H) -ọkan) (CAS: 381233-78-9), agbedemeji ti Perampanel (CAS: 380917-97-5).Perampanel (asẹ ni 2012) jẹ iran-kẹta AED ti a mọ pẹlu orukọ ami iyasọtọ ti Fycompa® (Eisai, Hatfield) ni UK ati Banzel® (Eisai, Hatfield) ni AMẸRIKA.Itọju ifọkansi ti awọn ijagba idojukọ pẹlu tabi laisi ijuwe keji ati awọn ijagba tonic-clonic gbogbogbo akọkọ.Ni Oṣu Kẹwa Ọdun 2012, US FDA fọwọsi perampanel fun itọju awọn ikọlu ibẹrẹ apakan ni awọn alaisan warapa ti o kere ju ọdun 12 ọdun.Perampanel jẹ alatako olugba olugba AMPA akọkọ lati gba ifọwọsi FDA bi AED.Awọn olugba AMPA glutamate ni a rii ni akọkọ lori awọn neuronu postsynaptic ninu ọpọlọ.Gẹgẹbi yiyan, antagonist ti ko ni idije ti AMPA, parampanel ṣe idiwọ ṣiṣi ikanni ion ati dinku itankale agbara iṣe.
