Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Mimọ>99.0% (HPLC)

Apejuwe kukuru:

Orukọ Kemikali: Lapatinib Ditosylate Monohydrate

CAS: 388082-78-8

Mimọ:> 99.0% (HPLC)

Irisi: Bialu Yellow to Yellow Crystalline Powder

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Alaye ọja

Jẹmọ Products

ọja Tags

Lapatinib Intermediates:

Kemikali Properties:

Orukọ Kemikali Lapatinib Ditosylate Monohydrate
Awọn itumọ ọrọ sisọ N-[3-chloro-4-[(3-fluorophenyl) methoxy] phenyl] -6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Nọmba CAS 388082-78-8
Iṣura Ipo O wa
Fọọmu Molecular C29H26ClFN4O4S·2(C7H8O3S)·H2O
Òṣuwọn Molikula 943.48
COA & MSDS Wa
Ipilẹṣẹ Shanghai, China
Brand Ruifu Kemikali

Awọn pato:

Nkan Awọn pato
Ifarahan Bia Yellow to Yellow Crystalline Powder
Mimọ / Analysis Ọna ≥99.0% (HPLC)
Ojuami Iyo 240.0 ~ 242.0 ℃
Ọrinrin (KF) 1.9 ~ 2.4%
Aimọ Kanṣoṣo ≤0.50%
Lapapọ Awọn Aimọ ≤1.00%
Awọn irin Heavy (gẹgẹbi Pb) ≤20ppm
Igbeyewo Standard Standard Enterprise
Lilo API;Fun itọju awọn alaisan ti o ni ọgbẹ igbaya

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

1

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388082-78-8 - Ohun elo:

Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) jẹ iyọ ditosylate tiCAS 231277-92-2, sintetiki kan, quinazoline ti nṣiṣe lọwọ ẹnu pẹlu iṣẹ ṣiṣe antineoplastic ti o pọju.O tun ṣe idiwọ phosphorylation ti olugba idagba ifosiwewe epidermal (EGFR), ErbB2, ati Erk-1 ati-2 ati AKT kinases;o tun ṣe idiwọ awọn ipele amuaradagba cyclin D ninu awọn laini sẹẹli tumo eniyan ati awọn xenografts.EGFR ati ErbB2 ti ni ipa ninu idagbasoke ti ọpọlọpọ awọn oriṣi tumo.O ti ṣe ifilọlẹ fun itọju ti ilọsiwaju tabi metastatic HER2 (ErbB2) akàn igbaya rere ninu awọn obinrin ti o ti gba itọju ailera iṣaaju.Oogun naa jẹ awari ati idagbasoke nipasẹ GlaxoSmithKline.

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