4,4′-Bis (2-Bromoacetyl) biphenyl CAS 4072-67-7 Daclatasvir Dihydrochloride Agbedemeji Mimọ> 98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti 4,4'-Bis (2-Bromoacetyl) biphenyl (CAS: 4072-67-7) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra 4,4'-Bis (2-Bromoacetyl) biphenyl,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | 4,4'-Bis (2-Bromoacetyl) biphenyl |
| Awọn itumọ ọrọ sisọ | 4,4'-Bis (Bromoacetyl) biphenyl;1,1'-[1,1'-Biphenyl] -4,4'-diylbis [2-Bromoethan-1-ọkan];Daclatasvir aimọ 7 |
| Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
| Nọmba CAS | 4072-67-7 |
| Fọọmu Molecular | C16H12Br2O2 |
| Òṣuwọn Molikula | 396,07 g / mol |
| Ojuami Iyo | 226.0 ~ 227.0 ℃ |
| iwuwo | 1,622 ± 0,06 g / cm3 |
| COA & MSDS | Wa |
| Ipilẹṣẹ | Shanghai, China |
| Ẹka | Agbedemeji ti Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Brand | Ruifu Kemikali |
| Awọn nkan | Awọn pato | Esi |
| Ifarahan | ri to | ri to |
| Mimọ / Analysis Ọna | > 98.0% (HPLC) | 98.5% |
| Infurarẹẹdi julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
| 1H NMR julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
| Ipari | Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun | |
| Ohun elo | Agbedemeji ti Daclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
4,4'-Bis (2-Bromoacetyl) biphenyl (CAS: 4072-67-7) jẹ agbedemeji ti Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir Dihydrochloride (Daklinza) jẹ inhibitor ti jedojedo C kokoro (HCV) NS5A ti o jẹ wulo ninu awọn itọju ti genotype 3 onibaje jedojedo C ikolu.
Ni Oṣu Keje Ọjọ 24, Ọdun 2015, FDA fọwọsi oogun jedojedo C onibaje (Bristol-Myers Squibb) fun titaja.
Ilana ifọwọsi FDA ti Daklinza (Bristol-Myers Squibb) ti ṣe awọn iyipo ati awọn iyipada.O ti kọ lẹẹkan nipasẹ FDA, ṣugbọn nikẹhin fọwọsi ni aarin-2015.FDA fọwọsi apapọ Daklinza ati Sofosbuvir fun itọju awọn alaisan jedojedo C iru 3.
Ni otitọ, ni kutukutu bi ṣaaju ifọwọsi FDA, Daklinza ti fọwọsi fun tita ni Japan, European Union ati South Korea ati awọn orilẹ-ede miiran.Ni ọdun 2014, eka ilera ara ilu Japanese fọwọsi ohun elo ti Daklinza ati Asunaprevir (Sunvepra) fun itọju genotype 1 ikolu.European Union tun fọwọsi Daclatasvir lati ṣee lo ni apapo pẹlu awọn oogun miiran ni itọju HCV genotypes 1, 2, 3 ati 4 ni ọdun 2014. Daclatasvir jẹ inhibitor eka NS5A akọkọ ti a fọwọsi nipasẹ European Union (EU).Nigbati a ba lo ni apapọ pẹlu awọn oogun miiran, ni akawe pẹlu apapọ itọju ti interferon ati ribavirin, eyiti o gba ọsẹ 48, o ni akoko itọju kukuru (ọsẹ 12 tabi ọsẹ 24).
A ko ṣe iṣeduro Daclathavir monotherapy, ilana akọkọ ti o wa lọwọlọwọ jẹ itọju ailera apapọ ti Dacastavir + Sofosbuvir, eyiti o jẹ ijuwe nipasẹ ipa ti o dara, SVR ti o ga julọ, awọn ipa ẹgbẹ kekere ati ọna itọju kukuru diẹ sii ju awọn aṣayan miiran lọ.
