Cyproheptadine Hydrochloride Sesquihydrate CAS 41354-29-4 Assay 98.5 ~ 100.5%
Ruifu Kemikali jẹ olupilẹṣẹ asiwaju ti Cyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, kekere ati awọn iwọn olopobobo ti o wa.Ra Cyproheptadine Hydrochloride Sesquihydrate,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | Cyproheptadine Hydrochloride Sesquihydrate |
Awọn itumọ ọrọ sisọ | 4- (5H-Dibenzo [a, d] cyclohepten-5-ylidene) -1-methylpiperidine Hydrochloride Sesquihydrate |
Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
Nọmba CAS | 41354-29-4 |
CAS ti o ni ibatan | 969-33-5 & 129-03-3 |
Fọọmu Molecular | C21H21N · HCl · 11 / 2H2O |
Òṣuwọn Molikula | 350,88 g / mol |
Ojuami Iyo | 165 ℃(oṣu kejila)(tan.) |
Omi Solubility | Ailesolusan ninu Omi |
Solubility | Tiotuka pupọ ni kẹmika.Soluble ni Chloroform.Tiotuka diẹ ni Ethanol.Insoluble ni Eteri |
COA & MSDS | Wa |
Apeere | Wa |
Ipilẹṣẹ | Shanghai, China |
Brand | Ruifu Kemikali |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | Funfun to Light Yellow Crystalline Powder | Ibamu |
Idanimọ | A. Infurarẹẹdi julọ.Oniranran yẹ ki o wa ni ibamu | Ibamu |
B. Yẹ ki o Ni ibamu | Ibamu | |
Chromatographic Mimọ | Yẹ ki o Ni ibamu | Ibamu |
Ayẹwo | 98.5 ~ 100.5% (Iṣiro lori ipilẹ Anhydrous) | 99.62% |
Omi nipa Karl Fischer | 7.0 ~ 9.0% | 8.2% |
Aloku lori Iginisonu | ≤0.10% | 0.08% |
Akitiyan | ≤0.15ml | ≤0.13ml |
Awọn irin Heavy | ≤10ppm | 8ppm |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto | Ibamu |
Ipari | Ọja yii nipasẹ ayewo ni ibamu pẹlu boṣewa USP35 | |
Igbesi aye selifu | Awọn ọdun 2 ti o ba fipamọ daradara |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati tọju ni itura, gbẹ (2 ~ 8℃) ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Cyproheptadine Hydrochloride
C21H21N · HCl · 1½H2O 350.88
Piperidine, 4- (5H-dibenzo [a, d] cyclohepten-5-ylidene) -1-methyl-, hydrochloride, sesquihydrate.
4- (5H-Dibenzo [a, d] cyclohepten-5-ylidene) -1-methylpiperidine hydrochloride sesquihydrate [41354-29-4].
Anhydrous 323.87 [969-33-5].
Cyproheptadine Hydrochloride ni ko kere ju 98.5 ogorun ati pe ko ju 100.5 ogorun ti C21H21N·HCl, ṣe iṣiro lori ipilẹ anhydrous.
Iṣakojọpọ ati ibi ipamọ- Ṣetọju ni awọn apoti ti o ni pipade daradara.
Awọn ajohunše Itọkasi USP <11>-
USP Cyproheptadine Hydrochloride RS
Idanimọ-
A: Gbigba infurarẹẹdi <197K>.
B: Gbigba Ultraviolet <197U>-
Solusan: 16 µg fun milimita.
Alabọde: oti.
Absorptivities ni 286 nm ko yato nipasẹ diẹ ẹ sii ju 3.0%.
C: Tu 100 miligiramu ti Cyproheptadine Hydrochloride ninu 10 milimita ti kẹmika.Gbe 1 ju ti ojutu sori iwe àlẹmọ, gbẹ, ati wiwo labẹ ina UV gigun-gigun kukuru: itanna bulu didan ni a ṣe akiyesi.
Acidity- Tu 1.0 g ti Cyproheptadine Hydrochloride ni 25 milimita ti methanol, fi methyl pupa TS kun, ati titrate pẹlu 0.10 N sodium hydroxide: ko ju 0.15 mL ti nilo (0.05% bi HCl).
Omi, Ọna I <921>: laarin 7.0% ati 9.0%.
Aloku lori ina <281>: ko ju 0.1%.
Awọn irin ti o wuwo, Ọna II <231>: 0.003%.
Assay-tu nipa 650 miligiramu ti Cyproheptadine Hydrochloride, ni iwọn deede, ni 50 milimita ti glacial acetic acid, alapapo lati tu.Dara, ṣafikun 10 milimita ti mercuric acetate TS, 0.5 milimita ti acetic anhydride, ati 1 ju ti violet crystal TS, ati titrate pẹlu 0.1 N perchloric acid VS si aaye ipari alawọ ewe.Ṣe ipinnu òfo, ki o si ṣe atunṣe to ṣe pataki.Olukuluku milimita ti 0.1 N perchloric acid jẹ deede si 32.39 mg ti C21H21N·HCl.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
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Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Awọn aami ewu Xn - ipalara
Awọn koodu ewu
R22 - ipalara ti o ba gbe
R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara.
Apejuwe Abo
S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun.
S36 - Wọ aṣọ aabo to dara.
UN ID UN 2811 6.1/PG 3
WGK Germany 3
RTECS TM7050000
HS koodu 2933399011
Ewu Kilasi 6.1
Iṣakojọpọ Ẹgbẹ III
Majele LD50 ẹnu ninu awọn eku: 74.2 mg/kg (Loux)
Cyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4) jẹ iru awọn antihistamines pipecolic, o le dije pẹlu histamini ti a tu silẹ lati ile-iṣẹ fun olugba H1 lori awọn sẹẹli ipa, nitorinaa o le ṣe idiwọ ibẹrẹ ti ifa inira, ati tu histamini silẹ- spasm ti a fa ati awọn ipa ipalọlọ, ọja yii ni antagonism olugba olugba H1 to lagbara, ipa antihistamine rẹ lagbara ju chlorpheniramine, promethazine.Awọn ipa anti-serotonin kekere ati iwọntunwọnsi wa ati awọn ipa anticholinergic.Ni afikun, nibẹ ni a lowo yanilenu ipa, ati àdánù anfani lẹhin kan awọn akoko.
Ile-iwosan Cyproheptadine hydrochloride sesquihydrate ti wa ni akọkọ ti a lo fun urticaria nla ati onibaje (paapaa urticaria tutu), urticaria papular, angioedema, àléfọ nkan ti ara, dermatitis olubasọrọ, aleji ounje, aleji oogun, rhinitis ti ara korira, iba koriko, aleji conjunctivitis ati migraine.O ni ipa itọju ailera kan lori ikọ-fèé.O tun le ṣee lo fun itọju adjuvant ti Aisan Cushing ati acromegaly.O tun le ṣee lo bi imudara igbadun fun awọn phobias neurotic.Awọn ijabọ wa ti itọju ti acanthosis nigricans ati idena ti pyoderma necrotizing.
Iṣẹ ati Ohun elo ti Cyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4)
1. Cyproheptadine Hydrochloride fun awọn itọju ti urticaria, nyún ara ati inira rhinitis.
2. Cyproheptadine Hydrochloride jẹ oogun tuntun kan ninu ẹgbẹ anticoagulant ati egboogi-allergic.O le ṣee lo fun awọn aati inira bi urticaria, àléfọ, inira ati olubasọrọ dermatitis ati pruritus.Urticaria, àléfọ, inira ati olubasọrọ dermatitis, pruritus, rhinitis, migraine ati ikọ-ara.Tun lo fun arun Cushing ati acromegaly.
3. Cyproheptadine Hydrochloride jẹ oogun egboogi-egbogi ti o lodi si iṣẹ ti histamini ninu ara lori awọn ohun elo ẹjẹ ati iṣan ti iṣan ti iṣan, nitorina imukuro awọn aami aiṣan ti ara korira.Cyproheptadine hydrochloride ni a lo fun awọn aati inira bi urticaria, àléfọ, inira ati olubasọrọ dermatitis ati awọ ara yun.