Apixaban Intermediate CAS 545445-44-1 Mimọ> 98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ ti 3-Morpholino-1- (4- (2-Oxopiperidin-1-yl) phenyl) -5,6-Dihydropyridin-2 (1H) -ọkan (CAS: 545445). -44-1) pẹlu didara to gaju, agbedemeji ti Apixaban (CAS: 503612-47-3).Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra Apixaban Intermediates,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | 3-Morpholino-1- (4- (2-Oxopiperidin-1-yl) phenyl) -5,6-Dihydropyridin-2 (1H) -ọkan |
| Awọn itumọ ọrọ sisọ | Apixaban Intermediate 1;5,6-Dihydro-3- (4-Morpholinyl) -1- [4- (2-Oxo-1-Piperidinyl) phenyl] -2 (1H) -Pyridinone;5-Morpholin-4-yl-1- [4- (2-Oxopiperidin-1-yl) phenyl] -2,3-Dihydropyridin-6-ọkan;Apixaban Impurity A |
| Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
| Nọmba CAS | 545445-44-1 |
| Fọọmu Molecular | C20H25N3O3 |
| Òṣuwọn Molikula | 355,43 g / mol |
| Ojuami Iyo | > 199 ℃ (oṣu kejila) |
| iwuwo | 1.267 g/ml |
| COA & MSDS | Wa |
| Ipilẹṣẹ | Shanghai, China |
| Ẹka | Agbedemeji ti Apixaban (CAS: 503612-47-3) |
| Brand | Ruifu Kemikali |
| Awọn nkan | Awọn pato | Esi |
| Ifarahan | Imọlẹ Yellow Powder | Imọlẹ Yellow Powder |
| Pipadanu lori Gbigbe | <0.50% | 0.16% |
| Aloku lori Iginisonu | <0.20% | 0.07% |
| Mimọ / Analysis Ọna | > 98.0% (Agbegbe HPLC) | 99.12% |
| Eyikeyi Olukuluku aimọ | <0.50% | <0.50% |
| Lapapọ Awọn Aimọ | <2.00% | 0.88% |
| 1H NMR julọ.Oniranran | Ni ibamu pẹlu Eto | Ni ibamu |
| LC-MS fun idanimọ | Ni ibamu | Ni ibamu |
| Ipari | Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun | |
| Ohun elo | Agbedemeji ti Apixaban (CAS: 503612-47-3) | |
Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
3-Morpholino-1- (4- (2-Oxopiperidin-1-yl) phenyl) -5,6-Dihydropyridin-2 (1H) -ọkan (CAS: 545445-44-1) jẹ agbedemeji ti Apixaban (CAS: 503612-47-3).
Apixaban jẹ oriṣi tuntun ti inhibitor Xa ifosiwewe ẹnu ni apapọ nipasẹ Bristol-Myers Squibb ati Pfizer.Orukọ iṣowo naa jẹ Eratol, eyiti o jẹ iru tuntun ti anticoagulant roba.Nipa idinamọ ifosiwewe coagulation pataki Xa, Apixaban le ṣe idiwọ iṣelọpọ thrombin ati thrombosis.Ni Oṣu Kẹrin Ọjọ 26, Ọdun 2007, Bristol-Myers Squibb darapọ mọ ọwọ pẹlu Pfizer lati kede ifowosowopo ni idagbasoke ti tuntun anticoagulant ti ẹnu Apixaban ohun ini nipasẹ Bristol-Myers Squibb bi yiyan igbegasoke si Warfarin.Ni Oṣu Karun ọdun 2011, Apixaban ni akọkọ lati fọwọsi idena ti iṣọn-ẹjẹ iṣọn-ẹjẹ ni awọn alaisan agbalagba ti o gba ibadi yiyan tabi iṣẹ abẹ rirọpo orokun ni awọn orilẹ-ede 27 EU, Iceland ati Norway.Ni Oṣu kọkanla ọjọ 20, Ọdun 2012, Igbimọ Yuroopu fọwọsi Ererto (Apixaban) fun idena ikọlu ati iṣọn-ẹjẹ eto ni awọn alaisan agbalagba ti o ni fibrillation atrial ti kii-valvular (NVAF) pẹlu ọkan tabi diẹ sii awọn okunfa eewu.Lẹhinna, Ile-iṣẹ Ounje ati Oògùn ti Ilu Kanada, Japan, ati US FDA fọwọsi Ererto (Apixaban) fun idena ikọlu ati iṣọn-ẹjẹ eto ni awọn alaisan agbalagba ti o ni fibrillation atrial ti kii-valvular (NVAF) pẹlu ọkan tabi diẹ sii awọn okunfa eewu.Ni Oṣu Kẹrin Ọjọ 12, Ọdun 2013, oogun anticoagulant tuntun Eloto (ELIQUIS)(Apixaban) ni apapọ ti o dagbasoke nipasẹ Bristol-Myers Squibb ati Pfizer ti kede ni ifowosi lati ṣe atokọ ni Ilu China.
![Apixaban Intermediate CAS 27143-07-3 Ethyl Chloro[(4-Methoxyphenyl) hydrazono] acetate Purity ≥99.0% (HPLC)](https://www.ruifuchemical.com/uploads/Apixaban-Intermediate-CAS-490-46-0-Factory-Shanghai-Ruifu-Chemical-Co.-Ltd.-www.ruifuchem.com_-300x300.jpg)
