5-Amino-3- (Trifluoromethyl) picolinonitrile CAS 573762-62-6 Apalutamide Intermediate Purity>98.0% (HPLC)
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ti 5-Amino-3- (Trifluoromethyl) picolinonitrile (CAS: 573762-62-6) pẹlu didara to gaju, agbedemeji ti Apalutamide (CAS: 956104-40-8).Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra Apalutamide Intermediates,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | 5-Amino-3- (Trifluoromethyl) picolinonitrile |
| Awọn itumọ ọrọ sisọ | 5-Amino-3- (Trifluoromethyl) pyridine-2-Carbonitrile;5-Amino-3- (Trifluoromethyl) 2-Cyanopyridine;5-Amino-2-Cyano-3- (Trifluoromethyl) pyridine;Apalutamide aimọ 10 |
| Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
| Nọmba CAS | 573762-62-6 |
| Fọọmu Molecular | C7H4F3N3 |
| Òṣuwọn Molikula | 187,12 g / mol |
| iwuwo | 1,45 ± 0,10 g / cm3 |
| COA & MSDS | Wa |
| Ipilẹṣẹ | Shanghai, China |
| Kíláàsì ewu | 6.1 |
| Iṣakojọpọ Ẹgbẹ | Ⅲ |
| Ẹka | Agbedemeji ti Apalutamide (CAS: 956104-40-8) |
| Brand | Ruifu Kemikali |
| Awọn nkan | Ayewo Standards | Esi |
| Ifarahan | Ina Yellow to Yellow ri to | Ibamu |
| Omi nipa Karl Fischer | <0.50% | 0.35% |
| Mimọ / Analysis Ọna | > 98.0% (HPLC) | 99.03% |
| Infurarẹẹdi julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
| 1H NMR julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
| Ipari | Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun | |
| Ohun elo | Agbedemeji ti Apalutamide (CAS: 956104-40-8) | |
Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
5-Amino-3- (Trifluoromethyl) picolinonitrile (CAS: 573762-62-6), jẹ pyridine heterocyclic Organic yellow, eyiti o le ṣee lo bi awọn agbedemeji elegbogi.5-Amino-3- (Trifluoromethyl) picolinonitrile jẹ agbedemeji ti Apalutamide (CAS: 956104-40-8).Apalutamide jẹ antiandrogen iran-keji ti a lo ninu itọju akàn pirositeti.O jẹ antagonist ti o lagbara ti olugba androgen pẹlu iye IC50 ti 16 nM.Di awọn olugba androgen, nitorina ni idinamọ translocation iparun, abuda DNA ati imuṣiṣẹ transcriptional.Apalutamide ni awọn ohun elo itọju ailera ni ti kii ṣe metastatic, akàn pirositeti sooro simẹnti.
Apalutamide ni a lo lati ṣe itọju awọn iru kan ti akàn pirositeti sooro simẹnti tabi akàn pirositeti ti ko tan si awọn ẹya miiran ti ara, ṣugbọn awọn itọju iṣoogun miiran ko ti ṣe iranlọwọ.Apalutamide wa ninu kilasi awọn oogun ti a pe ni awọn inhibitors receptor androgen.O ṣiṣẹ nipa didi awọn ipa ti androgen lati da idagba ati itankale awọn sẹẹli alakan duro.Ni Oṣu Kẹsan ọjọ 17, Ọdun 2019, Ile-iṣẹ Ounje ati Oògùn fọwọsi Apalutamide (ERLEADA, Janssen Biotech, Inc) fun awọn alaisan ti o ni akàn pirositeti ti o ni itara-ara metastatic (mCSPC).Apalutamide ni akọkọ ti fọwọsi ni ọdun 2018 fun awọn alaisan ti o ni akàn pirositeti ti kii-metastatic.
