Trelagliptin Succinate Intermediate CAS 865759-24-6 Mimo>98.0% (HPLC) Aworan Ifihan

Trelagliptin Succinate Intermediate CAS 865759-24-6 Mimọ>98.0% (HPLC)

Apejuwe kukuru:

Trelagliptin Succinate Intermediate-int D

CAS: 865759-24-6

Mimọ:> 98.0% (HPLC)

Irisi: Pa-White to Light Yellow Crystal

Agbedemeji ti Trelagliptin Succinate (CAS: 1029877-94-8) fun itọju ti Àtọgbẹ Iru 2

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Fi imeeli ranṣẹ si wa

Alaye ọja

Jẹmọ Products

ọja Tags

Apejuwe:

Ipese Iṣowo Trelagliptin Awọn agbedemeji ti o jọmọ Succinate:
6-Chloro-3-Methyluracil CAS 4318-56-3
2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Intermediate-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com

Kemikali Properties:

Orukọ Kemikali	Trelagliptin Succinate Intermediate-int D
Awọn itumọ ọrọ sisọ	2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1 (2H)) Methyl) -4-fluorobenzonitrile;2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluorobenzonitrile
Aimọ	Trelagliptin aimọ 17
Iṣura Ipo	Ninu Iṣura, Iwọn Iṣowo
Nọmba CAS	865759-24-6
Fọọmu Molecular	C13H9ClFN3O2
Òṣuwọn Molikula	293,68 g / mol
iwuwo	1,49 ± 0,10 g / cm3
Ibi ipamọ otutu.	Itura & Ibi Gbẹ
COA & MSDS	Wa
Brand	Ruifu Kemikali

Awọn pato:

Awọn nkan	Ayewo Standards	Esi
Ifarahan	Pa-White to Light Yellow Crystal	Ni ibamu
Idanimọ
HPLC	Akoko idaduro ti ayẹwo oke pataki ni ibamu si boṣewa itọkasi	Ni ibamu
IR - infurarẹẹdi julọ.Oniranran	IR Absorption sipekitira ti ayẹwo ati bošewa jẹ concordant	Ni ibamu
Ayewo
Pipadanu lori Gbigbe	<0.50%	0.3%
Lapapọ Awọn Aimọ	<2.00%	Ni ibamu
Mimọ / Analysis Ọna	> 98.0% (HPLC)	99.1%
Ipari	Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato

Package/Ipamọ/Gbigbe:

Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti edidi ni itura ati gbigbẹ ati ile itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.Yago fun imọlẹ;Afẹfẹ.
Gbigbe:Firanṣẹ si agbaye nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.

Awọn anfani:

Agbara to to: Awọn ohun elo to ati awọn onimọ-ẹrọ

Iṣẹ Ọjọgbọn: Iṣẹ rira iduro kan

OEM Package: Aṣa package ati aami wa

Ifijiṣẹ Yara: Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta

Ipese Idurosinsin: Ṣetọju ọja iṣura ti o tọ

Atilẹyin imọ-ẹrọ: Ojutu imọ-ẹrọ wa

Iṣẹ Iṣọkan Aṣa: Larin lati giramu si kilos

Didara to gaju: Ṣeto eto idaniloju didara pipe

FAQ:

Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.

Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.

Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.

DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl

Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.

Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.

MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.

Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.

Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.

Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.

Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.

Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.

Ohun elo:

2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1 (2H)-yl) Methyl) -4-fluorobenzonitrile (CAS: 865759-24-6) ni a lo bi agbedemeji ti Trelagliptin Succinate (CAS: 1029877-94-8).Trelagliptin Succinate, ni idagbasoke nipasẹ Takeda, Japan, ti a ṣe ifilọlẹ ni Oṣu Kẹta ọdun 2015, labẹ orukọ iṣowo Zafatek, ni a lo lati ṣe itọju àtọgbẹ iru 2.Trelagliptin jẹ oludena dipeptidyl peptidase IV (DPP-4) ti n ṣiṣẹ ni pipẹ nipasẹ yiyan ati ni idaduro nigbagbogbo DPP-4 lati ṣakoso awọn ipele suga ẹjẹ.Trelagliptin jẹ oogun hypoglycemic osẹ akọkọ ti o wa lori ọja, ati iru awọn inhibitors DPP-4 lori ọja nilo lati mu lẹẹkan ni ọjọ kan.Awọn anfani oogun Zafatek yoo laiseaniani pese awọn aṣayan itọju irọrun diẹ sii fun awọn alaisan alakan.O nireti lati mu irọrun ati ibamu ti awọn alaisan dara pupọ.ni Oṣu Kẹta Ọjọ 26, Ọdun 2015, omiran elegbogi Japanese ti Takeda kede pe oogun alakan tuntun Zafatek jẹ ifọwọsi nipasẹ Ile-iṣẹ ti ilera, iṣẹ ati iranlọwọ ti Japan (MHLW) fun itọju iru àtọgbẹ 2.Ifọwọsi naa samisi Zafatek di oogun oogun hypoglycemic oral akọkọ ti osẹ-ọsẹ lori ọja ni agbaye, ati pe o tun ṣe aṣoju blockbuster kan silẹ nipasẹ Takeda ni ọja alakan.
Trelagliptin jẹ oludena dipeptidyl peptidase IV (DPP-4) lẹẹkan-ọsẹ ti o ṣakoso awọn ipele suga ẹjẹ nipasẹ yiyan ati didimule DPP-4 nigbagbogbo.DPP-4 jẹ enzymu kan ti o le bẹrẹ inactivation ti incretin (glucagon-like peptide-1 (GLP-1) ati glucose-dependent insulinotropic polypeptide (GIP)), eyiti o ṣe ipa pataki ninu ilana glukosi ẹjẹ.Idinamọ ti DPP-4 le ṣe alekun yomijade insulin ti o gbẹkẹle ipele suga ẹjẹ, nitorinaa iṣakoso ipele suga ẹjẹ.Ifisilẹ Trelagliptin NDA da lori ipa ati data ailewu lati ọpọlọpọ awọn idanwo ile-iwosan ti ipele III ti a ṣe ni awọn alaisan Japanese ti o ni àtọgbẹ iru 2.Agbara ti Trelagliptin ti jẹrisi ni gbogbo awọn idanwo, ati pe o ni aabo to dara ati ifarada.Isakoso Trelagliptin lẹẹkan ni ọsẹ kan le ṣakoso ipele suga ẹjẹ ni imunadoko ati pe a nireti lati ni ilọsiwaju ibamu oogun awọn alaisan.