4-Chloro-6-Iodoquinazoline CAS 98556-31-1 Mimo>98.0% (HPLC) Aworan Ifihan

4-Chloro-6-Iodoquinazoline CAS 98556-31-1 Mimọ>98.0% (HPLC)

Apejuwe kukuru:

Orukọ Kemikali: 4-Chloro-6-Iodoquinazoline

CAS: 98556-31-1

Mimọ:> 98.0% (HPLC)

Irisi: Aye Yellow si Yellowish-Brown Powder

Agbedemeji ti Lapatinib / Lapatinib Ditosylate Monohydrate

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Apejuwe:

Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti 4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra 4-Chloro-6-Iodoquinazoline,Please contact: alvin@ruifuchem.com

Lapatinib Intermediates:

Lapatinib Ipilẹ	CAS 231277-92-2
Lapatinib Ditosylate Monohydrate	CAS 388082-78-8
Iṣuu soda Methanesulfinate	CAS 20277-69-4
3-Chloro-4- (3-Fluorobenzyloxy) aniline	CAS 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	CAS 98556-31-1
6-Iodo-4-Hydroxyquinazoline	CAS 16064-08-7
5-Formyl-2-Furanboronic Acid	CAS 27329-70-0
5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	CAS 231278-84-5

Kemikali Properties:

Orukọ Kemikali	4-Chloro-6-Iodoquinazoline
Awọn itumọ ọrọ sisọ	6-Iodo-4-Chloroquinazoline
Iṣura Ipo	Ni Iṣura, Iṣowo Iṣowo
Nọmba CAS	98556-31-1
Fọọmu Molecular	C8H4ClIN2
Òṣuwọn Molikula	290,49 g / mol
Ojuami Iyo	175.0 si 179.0 ℃
iwuwo	2,017 ± 0,06 g / cm3
Atọka Refractive n20/D	1.739
Ni imọlara	Afẹfẹ Ifamọ
COA & MSDS	Wa
Ipilẹṣẹ	Shanghai, China
Brand	Ruifu Kemikali

Awọn pato:

Awọn nkan	Ayewo Standards	Esi
Ifarahan	Aiye Yellow to Yellowish-Brown Powder	Earth Yellow Powder
Ojuami Iyo	175.0 si 179.0 ℃	177.2 ℃
Pipadanu lori Gbigbe	<1.00%	0.15%
Mimọ / Analysis Ọna	> 98.0% (HPLC)	98.43%
1H NMR julọ.Oniranran	Ni ibamu pẹlu Eto	Ibamu
Ipari	Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun
Ohun elo	Agbedemeji ti Lapatinib / Lapatinib Ditosylate Monohydrate

Package/Ipamọ/Gbigbe:

Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.

Awọn anfani:

Agbara to to: Awọn ohun elo to ati awọn onimọ-ẹrọ

Iṣẹ Ọjọgbọn: Iṣẹ rira iduro kan

OEM Package: Aṣa package ati aami wa

Ifijiṣẹ Yara: Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta

Ipese Idurosinsin: Ṣetọju ọja iṣura ti o tọ

Atilẹyin imọ-ẹrọ: Ojutu imọ-ẹrọ wa

Iṣẹ Iṣọkan Aṣa: Larin lati giramu si kilos

Didara to gaju: Ṣeto eto idaniloju didara pipe

FAQ:

Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.

98556-31-1 - Ohun elo:

4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) jẹ agbedemeji ninu iṣelọpọ ti Lapatinib (CAS: 231277-92-2) / Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8).
Lapatinib jẹ akàn igbaya tuntun ti o ni ifọkansi oogun ti o ni idagbasoke ati ti iṣelọpọ nipasẹ GlaxoSmithKline, eyiti a fọwọsi nipasẹ Ile-iṣẹ Ounje ati Oògùn AMẸRIKA ni Oṣu Kẹta Ọjọ 13, Ọdun 2007. Itọkasi ti a fọwọsi lọwọlọwọ ni idapo pẹlu capecitabine fun ilọsiwaju tabi akàn igbaya metastatic, ati awọn alaisan alakan igbaya igbaya. gbọdọ ṣe itọju pẹlu awọn oogun laini akọkọ miiran.Orukọ iṣowo rẹ ni Amẹrika ni Tykerb.Ni Oṣu Kejila ọjọ 14, Ọdun 2007, Ile-iṣẹ Oogun Yuroopu (EMEA) fọwọsi atokọ ti Lapatinib ni Yuroopu labẹ orukọ iṣowo Tyverb.Itọju ifọkansi molikula fun akàn igbaya n tọka si itọju awọn oncogenes ati awọn ọja ikosile ti o ni ibatan si iṣẹlẹ ati idagbasoke ti akàn igbaya.Awọn oogun ìfọkànsí molikula ṣe idiwọ tabi pa awọn sẹẹli tumo nipa didina ifihan ifihan ninu awọn sẹẹli tumo tabi awọn sẹẹli ti o jọmọ lati ṣakoso awọn iyipada ninu ikosile jiini sẹẹli.Lapatinib jẹ ẹya oral kekere moleku epidermal idagba ifosiwewe tyrosine kinase inhibitor.Awọn idanwo ile-iwosan ti fihan pe fun awọn alaisan alakan igbaya HER2 ti o ti ni idagbasoke resistance si Roche's Herceptin (Herceptin), Lapatinib ni ipa ile-iwosan to dara.Awọn idanwo in vitro, Lapatinib ni ipa inhibitory idagbasoke pataki lori Her-2 overexpressing awọn laini sẹẹli alakan igbaya.Ni Awọn idanwo Ipele I ti akàn igbaya ti o ti ni ilọsiwaju pẹlu Her-2 overexpression, Lapatinib tun ni oṣuwọn ti o munadoko ti o ga julọ ati pe ko ni idiwọ agbelebu si Herceptin (trastuzumab).Nitori eto rẹ jẹ moleku kekere, ko dabi Herceptin (trastuzumab), o le wọ inu idena ọpọlọ-ẹjẹ ati ni ipa itọju ailera kan lori metastasis ọpọlọ ti akàn igbaya.