Cetrorelix Acetate CAS 130143-01-0 GnRH Antagonist Peptide Purity (HPLC) ≥98.0% Didara to gaju
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti Cetrorelix Acetate (CAS: 130143-01-0) pẹlu didara to gaju.Cetrorelix Acetate jẹ homonu ti o tu silẹ gonadotropin (GnRH).Ruifu Kemikali n pese lẹsẹsẹ ti awọn peptides GMP.Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, kekere ati awọn iwọn olopobobo ti o wa.Ra Cetrorelix Acetate,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | Cetrorelix acetate |
| Awọn itumọ ọrọ sisọ | N-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-4-Chloro-D-Phenylalanyl-3-(3-Pyridinyl)-D-Alanyl-L-Seryl-L-Tyrosyl-N5-(Aminocarbonyl)- D-Ornithyl-L-Leucyl-L-Arginyl-L-Prolyl-D-Alaninamide Diacetate;NS-75A Diacetate;SB-075 Diacetate |
| Awọn ilana | Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala -NH2 |
| Nọmba CAS | 130143-01-0 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Kilograms |
| Fọọmu Molecular | C70H92N17O14 |
| Òṣuwọn Molikula | 1551.16 |
| Ibi ipamọ otutu. | Itura & Ibi Gbẹ (-20℃).Firiji |
| Igbesi aye selifu | > Awọn ọdun 2 ti o ba fipamọ daradara |
| Ẹka | Awọn Peptides GMP |
| Iwe aṣẹ | COA, MS, HPLC, NMR, MSDS, ati bẹbẹ lọ. |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun Powder |
| Peptide Mimọ (nipasẹ HPLC) | ≥98.0% (nipasẹ Isopọpọ Agbegbe) |
| Akoonu Peptide | ≥80.0% (nipasẹ%N) |
| Amino Acid Tiwqn | 10% ti Theetical |
| Akoonu Acetate | ≤10.0% (nipasẹ HPLC) |
| TFA akoonu | ≤1.0% |
| Aimọ Kanṣoṣo | ≤1.0% (nipasẹ HPLC) |
| Akoonu Omi (Karl Fischer) | ≤8.0% |
| Ayẹwo | 95.0 ~ 105.0% (Nipasẹ Anhydrous, Ọfẹ Acetic Acid) |
| MS | Dédédé |
| Igbeyewo Standard | Standard Enterprise |
| Sowo ibeere | Ice baagi, Desiccant baagi |
| Oti ti Ọja | Sintetiki |
| Ifarabalẹ | Fun Iwadi Nikan, Kii ṣe Fun Lilo Eniyan |
| Lilo | Sintetiki Atampako ti GnRH Olugba |
Apo:Vial ṣiṣu (igbẹhin fun iṣakojọpọ peptide) tabi vial gilasi, opoiye ni ibamu si ibeere alaye alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti edidi ni itura ati ki o gbẹ (2 ~ 8℃) ile itaja kuro lati awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Cetrorelix Acetate (CAS 130143-01-0) jẹ homonu ti o tu silẹ gonadotropin (GnRH) ti o ta ọja ni akọkọ labẹ orukọ iyasọtọ Cetrotide.Decapeptide sintetiki, ti a lo ni lilo ni iranlọwọ atunse lati dena awọn abẹ homonu luteinizing ti tọjọ.Oogun naa n ṣiṣẹ nipa didi iṣe ti GnRH sori pituitary, nitorinaa ni iyara ni idinku iṣelọpọ ati iṣe ti homonu luteinizing (LH) ati homonu ti o nfa follicle (FSH).Cetrorelix Acetate jẹ ti ọpọlọpọ awọn amino acids ti kii ṣe adayeba ti o ṣe idiwọ ovulation ni kutukutu ni awọn idanwo ile-iwosan, ti o yori si ikojọpọ ovulation ati iranlọwọ itọju imọ-ẹrọ ibisi fun awọn alaisan ti o ni itara ovarian iṣakoso.
Itọkasi Cetrorelix Acetate jẹ homonu atọwọda ti o ṣe idiwọ awọn ipa ti homonu itusilẹ gonadotropin (GnRH).Ninu imọ-ẹrọ ibisi ti iranlọwọ, ni awọn alaisan ti o ni itara ti ovarian iṣakoso, ṣe idiwọ ovulation ti tọjọ.
Iṣẹ iṣe elegbogi Cetrorelix Acetate jẹ homonu ti o tu silẹ gonadotropin (GnRH).GnRH le sopọ si awọn olugba awo awo ti awọn sẹẹli pituitary.Cetrorelix acetate ni ifigagbaga ni asopọ si awọn olugba wọnyi pẹlu GnRH endogenous, nitorinaa iwọn-igbẹkẹle ni idinamọ yomijade ti homonu luteinizing (LH) ati homonu safikun follicle (FSH) nipasẹ adenohypophysis.Ipa inhibitory ti ṣelọpọ lẹsẹkẹsẹ lẹhin iṣakoso ti cetrorelix acetate, ati pe ipa inhibitory le ṣe itọju nipasẹ itọju ilọsiwaju.fun awọn obirin, Cetrorelix Acetate le ṣe idaduro LH tente oke, nitorina idaduro ovulation.Fun awọn obinrin ti o ni itara ti ovarian, iye akoko iṣe jẹ igbẹkẹle iwọn lilo.Iwọn kan ti cetrorelix 3mg ni a ṣe ifoju pe o ni ipa inhibitory ti o kere ju awọn ọjọ 4, pẹlu ipa inhibitory ti isunmọ 70% ni Ọjọ 4. Atunse iṣakoso ti cetrorelix acetate 0.25mg ni gbogbo wakati 24 le ṣetọju ipa rẹ.Ipa homonu-antagonizing ti Cetrorelix Acetate ti yipada patapata ni opin itọju ni awọn ẹranko ati eniyan.
Iṣẹ ṣiṣe ti isedale Cetrorelix Acetate jẹ alatako ti o lagbara ti olugba GnRH pẹlu iye IC50 ti 1.21 nM.
Àkọlé IC50: 1,21 nM GnRH.
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