Cisatracurium Besylate CAS 96946-42-8 Assay 95.0%~102.0% API Factory Didara Giga
Olupese pẹlu Giga ti nw ati Idurosinsin Didara
Orukọ Kemikali: Cisatracurium Besylate
CAS: 96946-42-8
API Didara Giga, Iṣelọpọ Iṣowo
Orukọ Kemikali | Cisatracurium Besylate |
Nọmba CAS | 96946-42-8 |
NỌMBA CAT | RF-API13 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C53H72N2O12.2C6H5O3S |
Òṣuwọn Molikula | 1243.49 |
Ojuami Iyo | 90.0 ~ 93.0 ℃ |
Sowo Ipò | Labẹ Ibaramu otutu |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun tabi Fere Funfun Powder, Odorless, Die-die Hygroscopic |
Solubility | Tiotuka larọwọto ni dichloromethane, acetonitrile, tiotuka diẹ ninu omi |
Yiyi pato | -35.0° si -45.0° (C=10mg/ml, 0.1mg/ml benzene sulfonic acid) |
Idanimọ | Tu pẹlu dilute hydrochoric acid, dropwise dilute bismuth potasiomu iodide TS, awọn ojoriro ofeefee yoo ṣejade |
Idanimọ | 1. HPLC ;2. IR |
Ayẹwo | 95.0 ~ 102.0% (C65H82N2O18S2 lori ipilẹ ti o gbẹ) |
pH | 3.5 si 5.0 |
wípé & Awọ ti Solusan | Yẹ ki o jẹ Clear & Awọ |
Pipadanu lori Gbigbe | ≤2.0% |
Aloku lori Iginisonu | ≤0.20% |
Awọn irin Heavy | ≤20ppm |
Trans-Trans Isomer | ≤0.50% |
Cis-Trans Isomer | ≤0.50% |
Mono-quaternries | ≤1.50% |
Aimọ Olukuluku miiran | ≤1.50% |
Lapapọ Awọn Aimọ | ≤5.0% |
Opitika Isomer SS-Isomer | ≤1.50% |
Opitika Isomer RS- Isomer | ≤1.00% |
Sulfate | ≤50ppm |
Ethyl | ≤0.50% |
Acetone | ≤0.50% |
kẹmika kẹmika | ≤0.3% |
Dichloromethane | ≤0.06% |
Acetonitrile | ≤0.041% |
Methylbenzene | ≤0.089% |
Aseku Solvents Acetonitrile | ≤410ppm |
Igbeyewo Standard | Pharmacopoeia Kannada (CP) |
Lilo | Ohun elo elegbogi ti nṣiṣe lọwọ (API) |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
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Cisatracurium Besylate (CAS 96946-42-8) jẹ fọọmu iyọ sulfonate benzene ti atracurium.O jẹ iru ti artificially sintetiki ti kii-depolarizing isan relaxants pẹlu awọn oniwe-ipa iru bi tubocurarine.Iwọn itọju naa ko ni ipa lori ọkan, ẹdọ ati iṣẹ kidinrin.O tun ko ni ohun-ini ikojọpọ.O tun le fa itusilẹ ti histamini nigba lilo ni awọn iwọn nla.Fun isunmi iṣan tabi iṣakoso mimi ti o nilo ni iṣẹ abẹ, ni akawe pẹlu awọn oogun anesitetiki ti iṣan isanmi lọwọlọwọ, cisatracurium besylate ko ni iṣelọpọ nipasẹ ẹdọ tabi kidinrin, ati pe o ni iduroṣinṣin ọkan ati ẹjẹ;ipa rẹ ti isinmi iṣan jẹ awọn akoko 3 ti o lagbara bi atracurium laisi eyikeyi awọn ipa ẹgbẹ inu ọkan ati ẹjẹ.Cisatracurium besylate jẹ lilo akọkọ si akuniloorun gbogbogbo, ati pe o le ṣee lo ni lilo pupọ ni intubation, atọju ẹdọ ati ailagbara kidinrin, ti a lo ninu iṣẹ abẹ inu ọkan ati ẹjẹ ati awọn agbalagba ati awọn alaisan ọmọ wẹwẹ.Ti a bawe pẹlu atracurium, ọja yii ko ni awọn ipa ikolu ti o gbẹkẹle iwọn lilo ti itusilẹ histamini;sibẹsibẹ, aila-nfani ni pe awọn alaisan ti o ni ailagbara ẹdọ ati kidinrin yẹ ki o ṣakoso pẹlu iṣọra.Lati ọdun 1996 fun igba akọkọ ti oogun yii ti wọ ọja ni UK, awọn orilẹ-ede ajeji ti lo diẹdiẹ lati rọpo vecuronium ati atracurium gẹgẹbi akọkọ ti awọn isinmi iṣan iṣan.
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