Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Factory Didara Giga
Ipese pẹlu Iwa mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Dantrolene Sodium Salt Hydrate
CAS: 14663-23-1
Isinmi Isan Egungun.Calcium ikanni onidalẹkun
API Didara Giga, Iṣelọpọ Iṣowo
| Orukọ Kemikali | Dantrolene iṣuu soda Iyọ Hydrate |
| Awọn itumọ ọrọ sisọ | 1-[5- (4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Salt Hydrate |
| Nọmba CAS | 14663-23-1 |
| NỌMBA CAT | RF-API78 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
| Fọọmu Molecular | C14H11N4NaO5 |
| Òṣuwọn Molikula | 338.25 |
| Solubility | Tiotuka ni DMSO |
| Sowo Ipò | Sowo Labẹ Ibaramu otutu |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Yellowish-Osan si Orange Crystalline Powder.Ko si ẹri ti o han ti ibajẹ nipasẹ ọrọ ajeji |
| Idanimọ A | Gbigba IR (197K) |
| Idanimọ B | Akoko idaduro ti tente oke pataki ni chromatogram ti igbaradi idanwo naa ni ibamu si pe ninu chromatogram ti igbaradi boṣewa, bi a ti gba ninu idanwo naa. |
| Idanimọ C | Pade awọn ibeere ti idanwo ina fun iṣuu soda (191) |
| Idanimọ D | Apakan 1: Iwọn didun kan, funfun, ojoriro kirisita ti ṣẹda Apá 2: Awọn precipitate ko farasin Apá 3: Awọn precipitate dissolves patapata Apá 4: Ko si precipitate ti wa ni akoso |
| Akoonu Omi (nipasẹ KF) | 14.5% ~ 17.0% |
| Patiku Iwon | 90% kere ju 200um |
| Ayẹwo | 90.0% ~ 96.0% ti C14H10N405 lori ipilẹ anhydrous |
| Awọn nkan ti o jọmọ | (HPLC, Agbegbe%) |
| Agbo ti o jọmọ A | ≤0.15% |
| Agbo ti o jọmọ B | ≤0.50% |
| Agbo ti o jọmọ C | ≤0.30% |
| Awọn ohun elo ti o ku | |
| Ethanol | ≤2000ppm |
| kẹmika kẹmika | ≤2000ppm |
| Acetone | ≤2000ppm |
| DMF | ≤620ppm |
| Awọn irin Heavy | ≤10ppm |
| Igbesi aye selifu | ọdun meji 2 |
| Igbeyewo Standard | Orilẹ Amẹrika Pharmacopoeia (USP) |
| Lilo | Isinmi Isan Egungun.Calcium ikanni onidalẹkun |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), jẹ inhibitor molecule kekere ti antagonist olugba olugba ti Ryanodine ati inhibitor ikanni Calcium.Dantrolene Sodium Salt jẹ isinmi iṣan ti iṣan, eyiti o ṣe idiwọ ifasilẹ intracellular Ca 2 + lati inu reticulum sarcoplasmic.Blockade ti Ca2 + itusilẹ lati sarcoendoplasmic reticulum, ti o ni ibatan ti o ni ibatan si simi ati ihamọ ti awọn iṣan, ṣe ipilẹṣẹ ipa isinmi iṣan ti o ni ibatan pẹlu Dantrolene.Neurotoxicity ti a gbekalẹ nipasẹ iṣẹ-ṣiṣe glutamate ti a sọ ni ibamu si awọn igbega ti o pọ julọ ni awọn ipele cytoplasmic Ca2 +, ati pe Dantrolene jẹ itọkasi ni ibamu bi oluranlowo neuroprotective lodi si excitotoxicity ti neurotrasmitter.Dantrolene, Sodium Salt jẹ inhibitor ti RyR-1 ati RyR-3.
