DAPT (GSI-IX) CAS 208255-80-5 γ-Secretase Inhibitor Assay>98.0% (HPLC) Factory
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ti DAPT (GSI-IX) (CAS: 208255-80-5) pẹlu didara to gaju, Inhibitor γ-Secretase.Kemikali Ruifu n pese lẹsẹsẹ awọn amino acids ati awọn itọsẹ.A le pese ifijiṣẹ agbaye, kekere ati titobi pupọ ti o wa.Ra DAPT,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | DAPT |
| Awọn itumọ ọrọ sisọ | GSI-IX;γ-Secretase Inhibitor IX;gamma-Secretase Inhibitor;LY-374973;(3,5-Difluorophenylacetyl) -Ala-Phg-OtBu;(3,5-Difluorophenylacetyl) -L-Alanyl-L-2-Phenylglycine tert-Butyl Ester;N-[N- (3,5-Difluorophenacetyl)-L-Alanyl]-S-Phenylglycine t-Butyl Ester;(2S)-N- [2- (3,5-Difluorophenyl) acetyl] -L-Alanyl-2-Phenyl-glycine 1,1-Dimethylethyl Ester |
| Iṣura Ipo | O wa |
| Nọmba CAS | 208255-80-5 |
| Fọọmu Molecular | C23H26F2N2O4 |
| Òṣuwọn Molikula | 432.47 |
| iwuwo | 1,213 g / cm3 |
| Ojuami Iyo | 142.0 ~ 146.0 ℃ |
| Ni imọlara | Ooru kókó |
| Solubility | Tiotuka ni DMSO |
| Ibi ipamọ otutu. | Tọju ni 2-8 ℃ |
| COA & MSDS | Wa |
| Brand | Ruifu Kemikali |
| Awọn Gbólóhùn Aabo | 24/25 - Yago fun olubasọrọ pẹlu ara ati oju. | ||
| WGK Germany | 3 | HS koodu | 2922491990 |
| Awọn nkan | Ayewo Standards | Esi |
| Ifarahan | Funfun tabi Pa-White Crystalline Powder | Ni ibamu |
| Pipadanu lori Gbigbe | <0.40% | 0.21% |
| Aloku lori Iginisonu | <0.40% | 0.20% |
| Awọn irin Heavy (gẹgẹbi Pb) | ≤20ppm | <20ppm |
| Aseyori / Analysis Ọna | > 98.0% (HPLC) | 98.62% |
| Erogba nipa Elemental Analysis | 62.1 ~ 64.1% | Ni ibamu |
| Nitrojini nipasẹ Elemental Analysis | 6.20 ~ 6.70% | Ni ibamu |
| Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto | Ni ibamu |
| NMR julọ.Oniranran | Ni ibamu si Eto | Ni ibamu |
| Ipari | Ọja yii nipasẹ Awọn adehun Ayewo pẹlu Iwọn Idawọlẹ | |
| Igbesi aye selifu | Awọn oṣu 24 Lati Ọjọ iṣelọpọ ti o ba wa ni ipamọ daradara | |
Package: Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti edidi ni itura, gbigbẹ (itaja ni 2-8℃) ati ile-itaja afẹfẹ kuro ni awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
DAPT (GSI-IX) (CAS: 208255-80-5), apaniyan ti o lagbara ati pato ti γ-secretase.DAPT jẹ inhibitor ti γ-secretase (IC50 ninu awọn neuronu akọkọ eniyan = 115 nM fun lapapọ Aβ tabi 200 nM fun Aβ42 pataki).Isakoso ẹnu ti DAPT ti han lati dinku awọn ipele ti Aβ ni ọpọlọ jade, omi cerebrospinal ati pilasima lati awọn eku ati awọn eku.DAPT ṣe idiwọ ifihan agbara Notch eyiti o ṣe agbega iyatọ neuronal ti awọn sẹẹli iṣaaju.Ṣe ilọsiwaju awọn sẹẹli iPS laisi oncogenes KLF4 ati CMYC5.Seli permeable.A lo DAPT ninu iwadi ti dida β-amyloid.A ti ṣe afihan DAPT lati ṣe idiwọ ifihan agbara Notch ni awọn iwadii ti autoimmune ati awọn aarun lymphoproliferative, gẹgẹbi ALPS ati lupus erythematosus, bakannaa ninu idagbasoke sẹẹli alakan, angiogenesis, ati iyatọ ti awọn sẹẹli pipọ pipọ ti eniyan fa.Idilọwọ awọn ifihan agbara ogbontarigi ni fitiro.Idilọwọ lapapọ Aβ ati iṣelọpọ Aβ42 ni awọn aṣa akọkọ eniyan (awọn iye IC50 jẹ 115 ati 200 nM, lẹsẹsẹ) laisi ipa lori awọn ipele APPα ati APPβ.Ẹjẹ-ọpọlọ idankan permeable.3D Growth matrix paati ati paati ti cerebral organoid media iyato.
