Darifenacin Hydrobromide Darifenacin HBr CAS 133099-07-7 Agbeyewo ≥99.0% API Factory High Didara
Ipese Olupese pẹlu Iwa-mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Darifenacin Hydrobromide
CAS: 133099-07-7
Darifenacin hydrobromide jẹ antagonist olugba olugba muscarinic M3 ti a yan ti a lo lati ṣe itọju ailagbara ito ati iṣọn iṣọn àpòòtọ apọju.
API Didara Giga, Iṣelọpọ Iṣowo
Orukọ Kemikali | Darifenacin Hydrobromide |
Awọn itumọ ọrọ sisọ | Darifenacin HBr;UK-88525;Enablex |
Nọmba CAS | 133099-07-7 |
NỌMBA CAT | RF-API94 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
Fọọmu Molecular | C28H30N2O2.HBr |
Òṣuwọn Molikula | 507.46 |
Ojuami Iyo | 228.0 ~ 230.0 ℃ |
Solubility | DMSO: Soluble 20mg/ml, Clear |
Ibi ipamọ otutu | Tọju Igba pipẹ ni -20 ℃ |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun Crystalline Powder |
Solubility | Solublely Soluble in Methanol, Die-die Soluble ninu Omi ati Ailesoju Ni Iṣeṣe ni Chloroform |
Idanimọ IR | Spectrum ti ayẹwo ni ibamu si ti boṣewa itọkasi |
HPLC idanimọ | Akoko idaduro ti oke pataki ti ojutu ayẹwo ni ibamu si ti ojutu boṣewa |
Awọn nkan ti o jọmọ | |
O pọju.Aimọ Kanṣoṣo | ≤0.50% |
Lapapọ Awọn Aimọ | ≤1.0% |
Isomer opitika | ≤0.50% |
Awọn ohun elo ti o ku | |
Ethyl acetate | ≤0.50% |
Ethanol | ≤0.50% |
kẹmika kẹmika | ≤0.30% |
Acetone | ≤0.50% |
1-Butanol | ≤0.50% |
Pipadanu lori Gbigbe | ≤1.0% (Gbẹ ni 105 ℃ ninu ẹrọ gbigbẹ afẹfẹ ti afẹfẹ titi di iwuwo igbagbogbo) |
Aloku lori Iginisonu | ≤0.10% |
Awọn irin Heavy | ≤20ppm |
Ayẹwo | ≥99.0% (lori ipilẹ ti o gbẹ) |
Igbesi aye selifu | 24 osu |
Igbeyewo Standard | Standard Enterprise |
Lilo | API, Overactive Bọọlu |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Darifenacin Hydrobromide, Darifenacin HBr (CAS 133099-07-7), ohun orally ti nṣiṣe lọwọ, lẹẹkan ọjọ kan yiyan M3 olugba antagonist, ti a se igbekale fun awọn itọju ti overactive àpòòtọ ni alaisan pẹlu awọn aami aisan ti be ito incontinence, amojuto ati igbohunsafẹfẹ.Oogun naa ni yiyan ṣe idiwọ olugba M3 ni iṣan detrusor lakoko ti o tọju awọn olugba M1 ati M2 ti o gbagbọ pe o ni ipa ninu eto aifọkanbalẹ aarin ati iṣẹ inu ọkan ati ẹjẹ ni atele.Agbo naa ni akọkọ ni idagbasoke nipasẹ Pfizer ati iwe-aṣẹ si Novartis ati Bayer.