Darunavir CAS 206361-99-1 Alatako-HIV Mimo ≥99.0% API Didanuti Agbejade Isọdanu HIV giga
Olupese IpeseAwọn ọja ibatan Darunavir:
Daunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl) amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Orukọ Kemikali | Daunavir |
| Awọn itumọ ọrọ sisọ | TMC114;UIC-94017 |
| Nọmba CAS | 206361-99-1 |
| NỌMBA CAT | RF-API68 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
| Fọọmu Molecular | C27H37N3O7S |
| Òṣuwọn Molikula | 547.66 |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun tabi Pa-White Crystalline Powder |
| Idanimọ | MS/HNMR HPLC |
| Solubility | Tiotuka ni DMSO, Itukufẹ diẹ ninu Omi |
| Ojuami Iyo | 74.0 ~ 76.0 ℃ |
| Idanimọ | 1H NMR |
| Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
| Awọn nkan ti o jọmọ | |
| Max Nikan Aimọ | ≤0.30% |
| Lapapọ Awọn Aimọ | ≤1.0% |
| Awọn ohun elo ti o ku | Ethanol ≤0.30% |
| Pipadanu lori Gbigbe | ≤0.50% |
| Aloku lori Iginisonu | ≤0.10% |
| Awọn irin Heavy | ≤20ppm |
| Arsenic | ≤1.5ppm |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Daunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor Anti-HIV |
Package: Igo, apo apamọwọ Aluminiomu, Ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Darunavir (orukọ ami iyasọtọ Prezista, ti a mọ tẹlẹ bi TMC114) jẹ oogun inhibitor protease ti a lo lati tọju ikolu HIV.Darunavir jẹ aṣayan itọju ti OARAC ti a ṣeduro fun itọju-lainidi ati awọn agbalagba ati awọn ọdọ ti o ni iriri itọju.Darunavir jẹ iru tuntun ti kii ṣe peptide antiretroviral protease inhibitors ni itọju ailera Eedi.O jẹ idagbasoke akọkọ nipasẹ ẹka ile elegbogi Johnson ti Iceland, Tibotec.O jẹ ti bioavailability ti o ga julọ ni awọn inhibitors protease 6 (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir ati ABT378/r).Ó ń ṣiṣẹ́ nípa dídènà dídá àwọn patikulu fáírọ́ọ̀sì tuntun àti tí ó dàgbà dénú ojú àwọn sẹ́ẹ̀lì tí ó ní àkóràn àti dídènà protease ọlọjẹ náà.Nigbati ọja ba lo fun igba pipẹ, nigbagbogbo le dinku fekito ọlọjẹ HIV ninu ẹjẹ, pọ si iye awọn sẹẹli CD4, dinku aye ti akoran HIV, mu didara igbesi aye dara si ati gigun igbesi aye.O dara fun awọn agbalagba ti o ni kokoro HIV ṣugbọn ko ni ipa lori lilo awọn oogun antiretroviral ti o wa tẹlẹ.Oogun naa gbọdọ ni idapo pẹlu lilo awọn iwọn kekere ti ritonavir tabi awọn aṣoju antiretroviral miiran, lati le mu ilọsiwaju naa dara.Iṣẹ ṣiṣe antiviral ni fitiro ni a le ṣe ayẹwo nipasẹ jijakokoro ati awọn lymphocytes ti o ni arun onibaje ati awọn lymphocytes ninu ẹjẹ agbeegbe.
