Desmopressin Acetate CAS 16789-98-3 Peptide Purity (HPLC) ≥98.5% Factory
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti Desmopressin Acetate (CAS: 16789-98-3) pẹlu didara to gaju.Ruifu Kemikali n pese lẹsẹsẹ ti awọn peptides GMP.Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, kekere ati awọn iwọn olopobobo ti o wa.Ra Desmopressin Acetate,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | Desmopressin acetate |
| Awọn itumọ ọrọ sisọ | Desmopressin (Acetate);DDAVP;1- (3-Mercaptoropanoic Acid) -8-d-Arginine Vasopressin Monoacetate;8-d-Arginine-1- (3-Mercapto-Propanoic Acid) vasopresin Monoacetate;Adiuretin SD;Desmospray;Minirin;Oṣu Kẹjọ;Octostim;Presinex;Stimate |
| Ọkọọkan | Mpr-Tyr-Phe-Gln-Asn-Cys-Pro-DARg-Gly-NH2 (Mpr1 & Cys6 Afara) |
| Iṣura Ipo | O wa |
| Nọmba CAS | 16789-98-3 |
| Ilana molikula | C46H64N14O12S2.2(C2H4O2) |
| Òṣuwọn Molikula | 1189,32 g / mol |
| Ni imọlara | Hygroscopic.Ọrinrin Sensitive |
| Ibi ipamọ otutu. | Itura & Ibi Gbẹ (-20℃).Firiji Labẹ Inert Atmosphere |
| COA & MSDS | Wa |
| Ọjọ Ipari | Awọn oṣu 24 Lati Ọjọ iṣelọpọ ti o ba wa ni ipamọ daradara |
| Brand | Ruifu Kemikali |
| Awọn nkan | Ayewo Standards | Awọn abajade |
| Ifarahan | Funfun Fluffy Powder | Ibamu |
| Idanimọ nipa HPLC | Idaduro jẹ Kanna pẹlu nkan Itọkasi | Ibamu |
| Yiyi pato [α] 20/D | -72.0° si -82.0° (C=1, 1% HAc) | -75.7° |
| Amino Acid Tiwqn | Asp: 0.95 ~ 1.05 | 0.98 |
| Glu: 0.95 ~ 1.05 | 0.98 | |
| Pro: 0.95 ~ 1.05 | 1.01 | |
| Gly: 0.95 ~ 1.05 | 1.00 | |
| Arg: 0.95 ~ 1.05 | 1.01 | |
| Phe: 0.95 ~ 1.05 | 0.97 | |
| Tir: 0.70 ~ 1.05 | 0.99 | |
| Sisi: 0.30 ~ 1.05 | 0.78 | |
| Peptide Mimọ (HPLC) | ≥98.5% | 99.3% |
| Ohun to jọmọ (HPLC) | Lapapọ Awọn aimọ: ≤ 1.5% | 0.78% |
| Aimọ Ẹyọkan ti o tobi julọ: ≤ 0.5% | 0.16% | |
| Akoonu Acetate (HPLC) | 3.0 ~ 8.0% | 7.6% |
| Akoonu Omi (Karl Fischer) | ≤6.0% | 1.0% |
| Ailesabiyamo | ≤50 CFU/100 mg | Ibamu |
| Awọn endotoxins kokoro arun | ≤5 IU/mg | Ibamu |
| Ayẹwo | 95.0 ~ 105.0% (Anhydrous, Acetic Acid Ọfẹ) | 98.6% |
| Oti ti Ọja | Sintetiki | Sintetiki |
| Ifarabalẹ | Fun Iwadi Nikan, Kii ṣe Fun Lilo Eniyan | |
| Ipari | Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato | |
Apo:Vial ṣiṣu (igbẹhin fun iṣakojọpọ peptide) tabi vial gilasi, opoiye ni ibamu si ibeere alaye alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti edidi ni itura ati ki o gbẹ (-20℃) ile itaja kuro lati awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Awọn aami ewu Xn - ipalara
Awọn koodu Ewu 20 - Ipalara nipasẹ ifasimu
Apejuwe Aabo 36 - Wọ aṣọ aabo to dara.
WGK Germany 3
Desmopressin Acetate (CAS: 16789-98-3) iyẹn ni, 1-cysteine deamination ati 8-D-arginine dipo 8-l-arginine, ti a tun mọ ni arginine vasopressin, jẹ afọwọṣe igbekale ti ara arginine vasopressin, itọsẹ ti vasopressin, ipa antidiuretic rẹ lagbara ati pipẹ ju vasopressin, ṣugbọn ko si ipa vasoconstrictor, awọn ipa ẹgbẹ oogun, ile-iwosan fun aibikita tabi ailagbara platelet ti oogun, uremia, cirrhosis ẹdọ ati awọn idi aimọ ti o fa nipasẹ akoko ẹjẹ gigun;Le ṣee lo lati ṣakoso ati dena ẹjẹ lakoko iṣẹ abẹ kekere;Central àtọgbẹ insipidus.Ni awọn ọran kọọkan, ọja yii yoo paapaa gbejade ipa ni awọn alaisan ti o ni awọn aarun eto ito iwọntunwọnsi, nigbagbogbo alaabo ni awọn alaisan ti o ni arun Iru IIB von Willebrand.
Ise elegbogi: Desmopressin Acetate ni desmopressin ti o jọra ti ara si arginine vasopressin.O jẹ iyatọ laarin arginine vasopressin, nipataki fun idaji amino acid ati D arginine lati rọpo L Arginine.Awọn ayipada igbekalẹ wọnyi ṣe gigun akoko iṣe ti iwọn lilo ile-iwosan ti desmopressin laisi awọn ipa ẹgbẹ ti funmorawon.Diẹ ninu awọn ijinlẹ ti fihan pe ipa ti anti-enuresis jẹ pataki, eyiti o le jẹ nitori ilosoke ti arginine vasopressin ninu ẹjẹ awọn ọmọde ni alẹ, ati lẹhinna ṣojumọ ito, dinku iwọn ito ati titẹ iṣan inu, ọrun ti o dinku ati ihamọ detrusor.
Ipa rẹ, irọrun ti iṣakoso (intranasal), iye akoko pipẹ ti iṣe, ati aini awọn ipa ẹgbẹ jẹ ki o jẹ oogun yiyan fun itọju ti àtọgbẹ aarin.O tun le ṣe abojuto intramuscularly orintravenously.O jẹ abẹrẹ vasopressin ati awọn antidiuretics ẹnu fun lilo ninu awọn ọmọde.O jẹ itọkasi iṣakoso ti polydipsia igba diẹ ati polyurias ti o ni ibatan pẹlu ibalokanjẹ si, tabi iṣẹ abẹ ninu, agbegbe pituitary.
Lilo Isẹgun: Desmopressin, bi iyọ acetate rẹ, jẹ afọwọṣe sintetiki ti vasopressin ninu eyiti N ebute Cys ko ni iṣẹ α-amino rẹ (1-Deamino) ati nibiti Arg8 wa bi D-isomer (D-Arg8) , bayi ni owo adape DDAVP.Iwaju D-Arg ati isansa ti amine N-terminal ninu eto desmopressin ti pọ si idaji-aye rẹ gẹgẹbi o wa fun ẹnu, parenteral, tabi lilo imu.O jẹ lilo nipasẹ gbogbo awọn ọna iṣakoso mẹta wọnyi lati ṣe idiwọ tabi ṣakoso polydipsia (ongbẹ pupọju), polyuria, ati gbigbẹ ti awọn alaisan ti o ni insipidus àtọgbẹ ti o fa nipasẹ aipe ti vasopressin.O tun ti fọwọsi fun itọju ti enuresis nocturnal (ibusun-wetting), eyiti o gbagbọ pe o fa nipasẹ isansa ti akoko alẹ deede dide ni awọn ipele vasopressin.Desmopressin ni a mọ lati fa ilosoke ninu ifosiwewe pilasima mejeeji VIII (ifosiwewe antihemophilic) ati plasminogen activator.Nitorina o jẹ ifọwọsi nipasẹ US FDA fun lilo, parenterally ati imu, ni idinku lẹẹkọkan tabi awọn iṣẹlẹ ẹjẹ ti o fa ibalokanjẹ ni awọn alaisan ti o ni hemophilia A ati iru I Von Willebrand's arun, ti o ba jẹ pe iṣẹ ṣiṣe VIII pilasima wọn tobi ju 5%.Stimate, ifun imu ti a lo ni itọju awọn alaisan ti o ni hemophilia A ati iru I Von Willebrand's arun, jẹ 15-agbo ifọkansi ti DDAVP imu spray;A lo igbehin ni itọju insipidus àtọgbẹ.
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