Desquinolinyl Lenvatinib CAS 796848-79-8 Mimọ>99.0% (HPLC) Ile-iṣẹ Agbedemeji Lenvatinib Mesylate
Ipese Kemikali Ruifu Lenvatinib Mesylate Intermediates Pẹlu Iwa mimọ to gaju
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Orukọ Kemikali | 1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea |
Awọn itumọ ọrọ sisọ | Desquinolinyl Lenvatinib;Lenvatinib Aimọ 16;Lenvatinib Desquinolinyl Aimọ;Lenvatinib Aimọ LFS-A;Lenvatinib Mesylate Intermediate Ⅲ;N-(2-Chloro-4-Hydroxyphenyl)-N'-Cyclopropyl-Urea |
Nọmba CAS | 796848-79-8 |
NỌMBA CAT | RF-PI1972 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C10H11ClN2O2 |
Òṣuwọn Molikula | 226.66 |
Ojuami farabale | 364,6 ± 42,0 ℃ |
iwuwo | 1,43 ± 0,10 g / cm3 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Pa-White to Pupa Brown Ri to Powder |
Mimọ / Analysis Ọna | > 99.0% (HPLC) |
Ọrinrin (KF) | <0.50% |
Aloku lori Iginisonu | <0.20% |
Aimọ Kanṣoṣo | <0.50% |
Lapapọ Awọn Aimọ | <1.00% |
Awọn irin Heavy | <10ppm |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto |
NMR | Ni ibamu si Eto |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti Lenvatinib Mesylate (CAS: 857890-39-2) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea, ti a tun mọ ni Desquinolinyl Lenvatinib, (CAS: 796848-79-8) jẹ agbedemeji tabi aimọ ti Lenvatinib Mesylate (CAS: 857890-39-2).Desquinolinyl Lenvatinib jẹ metabolite ti Lenvatinib Mesylate eyiti o jẹ inhibitor ti nṣiṣe lọwọ ẹnu ti ọpọlọpọ awọn kinases tyrosine olugba pẹlu VEGF, FGF ati awọn olugba SCF.Lenvatinib jẹ oogun egboogi-akàn fun itọju awọn iru kan ti akàn tairodu, ati agbara fun awọn aarun miiran pẹlu.Ni Oṣu Keji ọjọ 13, Ọdun 2015, US FDA fọwọsi oogun anticancer Lenvatinib fun itọju akàn tairodu.Lenvatinib jẹ inhibitor enzymu-pupọ-afojusun, ti o lagbara lati dena VEGFR2 ati VEGFR3 (igbasilẹ ifosiwewe idagbasoke endothelial ti iṣan).Orukọ iṣowo ti Lenvatinib jẹ Lenvima.