Diethylphosphonoacetic Acid CAS 3095-95-2 Mimo>99.5% (HPLC) Afatinib Dimaleate Agbedemeji Factory
Ruifu Kemikali Ipese Intermediates of Afatinib
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Diethylphosphonoacetic Acid CAS 3095-95-2
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7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
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Orukọ Kemikali | Diethylphosphonoacetic Acid |
Awọn itumọ ọrọ sisọ | 2- (Diethoxyphosphosphoryl) acetic Acid;(Diethoxyphosfinyl) acetic Acid;Diethyl Carboxymethylphosphonate;NSC 272281 |
Nọmba CAS | 3095-95-2 |
NỌMBA CAT | RF-PI2024 |
Iṣura Ipo | Ni Iṣura, Agbara iṣelọpọ 30MT / osù |
Ilana molikula | (C2H5O) 2P (O) CH2CO2H |
Òṣuwọn Molikula | 196.14 |
Ojuami farabale | 150℃/0.05 mmHg (tan.) |
iwuwo | 1.220 g/mL ni 25 ℃ (tan.) |
Atọka Refractive | n20/D 1.445 (tan.) |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Omi ti ko ni awọ |
Idanimọ (HPLC) | Akoko idaduro ti tente oke akọkọ ti a gba lati inu ayẹwo wa laarin 5% ti itọkasi itọkasi. |
Mimọ / Analysis Ọna | > 99.5% (HPLC) |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto |
Proton NMR julọ.Oniranran | Ni ibamu si Eto |
Ọrinrin (KF) | <0.50% |
Lapapọ Awọn Aimọ | <0.50% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti Afatinib Dimaleate (CAS: 850140-73-7) |
Package: Igo Fluorinated, 25kg / Ilu, tabi ni ibamu si ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Diethylphosphonoacetic Acid (CAS: 3095-95-2), Awọn iṣe bi nucleophile fun awọn aati afikun nucleophilic fun iṣelọpọ ti epoxides allene Reactant fun: Awọn ijinlẹ Stereoselectivity ti iṣesi Staudinger;Ipilẹṣẹ Enantioselective ti awọn diol nipasẹ epoxidiation ati awọn aati hydration;Awọn aati Horner-Wadsworth-Emmons;Latọna chelation dari Ireland-Claisen atunto;Awọn aati Ugi-Dieckmann fun iṣelọpọ ti awọn itọsẹ tetramic acid;Ti a lo lati ṣe awọn agbedemeji phosphonoester fun awọn aati HEW intramolecular.Diethylphosphonoacetic Acid jẹ agbedemeji Afatinib Dimaleate (CAS: 850140-73-7).Afatinib Dimaleate jẹ ifọwọsi nipasẹ Awọn ipinfunni Ounje ati Oògùn AMẸRIKA (FDA) ni ọdun 2013 fun itọju ti akàn ẹdọfóró sẹẹli ti kii ṣe kekere (NSCLC).Ni pataki, o fọwọsi fun awọn alaisan ti n ṣafihan pẹlu awọn èèmọ NSCLC metastatic eyiti o ni awọn piparẹ awọn imukuro ti o ni idagba ifosiwewe epidermal (EGFR) tabi awọn iyipada exon 21.Afatinib Dimaleate jẹ oludanukokoro covalent ti ErbB tyrosine kinases (tyk), eyiti o ṣe atunṣe ami ifihan ErbB nipasẹ isọdọkan ti ko yipada ti awọn aaye abuda EGFR tyk.