Docetaxel CAS 114977-28-5 Assay 98.0% ~ 102.0%
Shanghai Ruifu Kemikali Co., Ltd jẹ oluṣakoso asiwaju ti Docetaxel (Taxotere) (CAS: 114977-28-5) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra Docetaxel,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | Docetaxel |
| Awọn itumọ ọrọ sisọ | Taxotere;Taxotere Anhydrous;Docetaxel Anhydrous;N-Debenzoyl-N-tert-Butoxycarbonyl-10-Deacetyltaxol;RP-56976 |
| Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
| Nọmba CAS | 114977-28-5 |
| Fọọmu Molecular | C43H53NO14 |
| Òṣuwọn Molikula | 807,89 g / mol |
| Ojuami Iyo | 186.0 ~ 192.0 ℃ (oṣu kejila) |
| iwuwo | 1.38 |
| Solubility | Tiotuka pupọ ni acetone, Dimethylformamide.Soluble ni Ethanol, Dichloromethane, kẹmika.Ailopin ninu Omi |
| COA & MSDS | Wa |
| Ipilẹṣẹ | Shanghai, China |
| Brand | Ruifu Kemikali |
| Awọn nkan | Awọn pato | Esi |
| Ifarahan | Funfun Crystalline Powder | Funfun Crystalline Powder |
| Idanimọ | IR & HPLC | Ni ibamu |
| Yiyi pato [a] 20/D | -42.0° si -45.0° (C=1 ninu EtOH) | -43.1° |
| Pipadanu lori Gbigbe | <3.00% | 2.05% |
| Aloku lori Iginisonu | <0.10% | 0.04% |
| Awọn Irin Eru (Pb) | ≤20ppm | <20ppm |
| Arsenic (Bi) | ≤1.5ppm | <1.5ppm |
| Awọn nkan ti o jọmọ | ||
| O pọju Nikan Aimọ | <0.50% | <0.50% |
| Lapapọ Awọn Aimọ | <1.00% | <1.00% |
| Makirobia Idiyewo | ||
| TAMC | ≤100cfu/g | <100cfu/g |
| TYMC | ≤10cfu/g | <10cfu/g |
| Awọn endotoxins kokoro arun | ≤0.3IU/mg | <0.3IU/mg |
| Aseyori / Analysis Ọna | 98.0% ~ 102.0% (Lori Anhydrous ati Ipilẹ Ọfẹ) | 100.9% |
| Ipari | Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun | |
Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ibi ipamọ:Jeki apo eiyan naa ni wiwọ ni pipade ati tọju ni itura, gbẹ (2 ~ 8℃) ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.Ibamu pẹlu awọn aṣoju oxidizing lagbara.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Awọn aami ewu Xi - Irritant
Awọn koodu ewu
R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara.
R61 - Le fa ipalara si awọn unborn ọmọ
Apejuwe Abo
S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun.
S36/37 - Wọ aṣọ aabo ati awọn ibọwọ to dara.
S53 - Yago fun ifihan - gba awọn ilana pataki ṣaaju lilo.
S45 - Ni ọran ti ijamba tabi ti o ba ni ailara, wa imọran iṣoogun lẹsẹkẹsẹ (fi aami han nigbakugba ti o ṣee ṣe.)
UN ID 1544
WGK Germany 3
RTECS DA4172750
HS koodu 2932999029
Ewu Kilasi 6.1(b)
Iṣakojọpọ Ẹgbẹ III
Majele ti LD50 iṣan ninu aja: 2500ug/kg
Docetaxel (Taxotere) (CAS: 114977-28-5) ti a ta bi Taxotere tabi Docecad, jẹ oogun egboogi-mitotic chemotherapy ti a ti fi idi mulẹ ti o ṣiṣẹ nipasẹ kikọlu pẹlu pipin sẹẹli.Docetaxel jẹ itẹwọgba nipasẹ FDA fun itọju ti ilọsiwaju ti agbegbe tabi akàn igbaya metastatic, akàn ori ati ọrun, akàn inu, akàn pirositeti ti homonu ati akàn ẹdọfóró sẹẹli kekere.Docetaxel le ṣee lo bi oluranlowo ẹyọkan tabi ni apapo pẹlu awọn oogun chemotherapeutic miiran bi itọkasi da lori iru akàn kan pato ati ipele.Docetaxel jẹ ọmọ ẹgbẹ ti kilasi oogun ti taxori, eyiti o tun pẹlu paclitaxel oogun chemotherapeutic.Botilẹjẹpe docetaxel wa ni ilopo bi agbara bi paclitaxel (nitori ipa docetaxel lori centrosome ti spindle mitotic), awọn owo-ori meji ni a ti ṣakiyesi lati ni ipa ti o jọra.Ọpọlọpọ awọn nkan aipẹ ti ri “ko si ẹri pe awọn ilana ti o ni docetaxel mu awọn anfani ti o tobi ju awọn ti o wa pẹlu paclitaxel lọ.”Lakoko ti o ti ṣe akiyesi ipa laarin awọn aṣoju meji lati jẹ deede, paclitaxel le fa awọn ipa ẹgbẹ diẹ.Ni afikun, o ti ṣe akiyesi pe docetaxel jẹ itara si resistance oogun cellular nipasẹ ọpọlọpọ awọn ọna ṣiṣe oriṣiriṣi.
1. Docetaxel jẹ oogun oogun kemoterapi ti a fi idi mulẹ daradara ti ile-iwosan (iyẹn ni, o dabaru pẹlu pipin sẹẹli).
2. A lo Docetaxel ni pataki fun itọju igbaya, ovarian, ati akàn ẹdọfóró sẹẹli ti kii ṣe kekere.
3. Docetaxel ni ẹtọ FDA ti a fọwọsi fun itọju awọn alaisan ti o ti ni ilọsiwaju ti agbegbe, tabi ọmu metastatic tabi akàn ẹdọfóró ti kii ṣe sẹẹli kekere ti o ti ṣe kimoterapi orisun anthracycline ati kuna lati da ilọsiwaju alakan duro tabi tun pada.Doce-taxel ifọwọsi ti Yuroopu fun lilo ninu akàn pirositeti homonu-refractory.
4. Docetaxel ni a ka pe o dara ju , bi antimicrotubule cytotoxic.
