Entecavir CAS 142217-69-4 API Factory Didara Giga Anti-HBV

Apejuwe kukuru:

Orukọ: Entecavir

CAS: 142217-69-4

Irisi: White Crystalline Powder

Oogun egboogi ti a lo ninu itọju Ẹdọ-arun B

API Didara Giga, Iṣelọpọ Iṣowo

Inquiry: alvin@ruifuchem.com


Alaye ọja

Jẹmọ Products

ọja Tags

Apejuwe:

Ipese Olupese pẹlu Iwa-mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Entecavir
CAS: 142217-69-4
Oogun egboogi ti a lo ninu itọju Ẹdọ-arun B
API Didara Giga, Iṣelọpọ Iṣowo

Kemikali Properties:

Orukọ Kemikali Entecavir
Awọn itumọ ọrọ sisọ 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3- (hydroxymethyl) -2-methylenecyclopentyl]-6H-purin-6-ọkan
Nọmba CAS 142217-69-4
NỌMBA CAT RF-API80
Iṣura Ipo Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular C12H15N5O3
Òṣuwọn Molikula 277.28
Ojuami Iyo 249.0 ~ 252.0 ℃
Brand Ruifu Kemikali

Awọn pato:

Nkan Awọn pato
Ifarahan Funfun Crystalline Powder
Idanimọ IR Iwọn gbigba infurarẹẹdi ti ayẹwo idanwo gbọdọ jẹ ibamu pẹlu boṣewa itọkasi
HPLC idanimọ Akoko idaduro ti ayẹwo idanwo ni ibamu si ti boṣewa itọkasi
pH 5.5 ~ 7.5
Specific Optical Yiyi +24.0°-+28.0° (DMF: MeOH=1:1 C=1%)
Awọn nkan ti o jọmọ
Lapapọ Awọn Aimọ ≤0.30%
O pọju Nikan Aimọ ≤0.10%
Enantomer ≤0.20%
Awọn ohun elo ti o ku
kẹmika kẹmika ≤0.30%
Dichloromethane ≤0.06%
n-Hexane ≤0.029%
Tetrahydrofuran ≤0.072%
N, N-Dimethylformamide ≤0.088%
Toluene ≤0.089%
Omi akoonu 5.8% ~ 6.5%
Aloku lori Iginisonu ≤0.10%
Awọn irin Heavy ≤20ppm
Ayẹwo 98.0% ~ 102.0% (C12H15N5O3 ṣe iṣiro lori ipilẹ anhydrous)
Patiku Iwon D90: ≤100µm
Igbeyewo Standard Standard Enterprise
Lilo API, Oogun Agbogun ti a lo ni itọju Ẹdọ-arun B

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

1

FAQ:

Ohun elo:

Entecavir jẹ iran tuntun ti awọn analogues guanine nucleoside analogues oogun ẹnu fun itọju ti Iwoye Ẹdọ B (HBV), nipataki fun itọju awọn alaisan agbalagba ti o ni iṣẹ ṣiṣe atunwi gbogun ati transaminase omi ara ti tẹsiwaju lati pọ si, tabi àsopọ ẹdọ fun iṣẹ-aisan ti arun jedojedo B onibaje. , Lọwọlọwọ ni isalẹ kokoro ni iyara ati alagbara julọ, iwọn iyipada ti o kere julọ awọn analogues nucleoside.Data fihan pe o yatọ si ni awọn alaisan ti o ni arun jedojedo B onibaje, pẹlu nucleoside naive ati nucleoside mu ati ẹdọ cirrhosis alaisan, lilo daradara entecavir wàláà ninu awọn itọju le šakoso awọn arun nyara ati awọn iṣọrọ de ọdọ awọn itọju ti otito opin, eyun awọn jedojedo B kokoro unmesured;nipasẹ ifaramọ si itọju, ipin pupọ ti awọn alaisan le de opin itẹlọrun itọju, eyun e antigen serology iyipada, diẹ ninu awọn alaisan le paapaa de ibi ti o dara julọ fun itọju ipari, eyun antigen odi.

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