Entecavir Monohydrate CAS 209216-23-9 API Factory High Quality Antiviral Hepatitis B Ikolu

Apejuwe kukuru:

Orukọ Kemikali: Entecavir Monohydrate

CAS: 209216-23-9

Irisi: Funfun tabi Fere White Crystalline Powder

Oogun egboogi ti a lo ninu itọju Ẹdọ-arun B

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Apejuwe:

Ipese Olupese pẹlu Iwa-mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Entecavir Monohydrate
CAS: 209216-23-9
Ti a lo ni itọju Ẹdọ-arun B
API Didara Giga, Iṣelọpọ Iṣowo

Kemikali Properties:

Orukọ Kemikali	Entecavir Monohydrate
Awọn itumọ ọrọ sisọ	Entecavir Hydrate;9-[(1S,3R,4S)-4-Hydroxy-3- (hydroxymethyl) -2-methylenecyclopentyl] guanine Monohydrate
Nọmba CAS	209216-23-9
NỌMBA CAT	RF-API79
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C12H17N5O4
Òṣuwọn Molikula	295.3
Ojuami Iyo	> 220 ℃
iwuwo	1.81
Sowo Ipò	Sowo Labẹ Ibaramu otutu
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun tabi Fere White Crystalline Powder
Solubility	Soluble Larọwọto ni Dimethylformamide, Tiotuka Diẹ ninu Omi, Ethanol ati Methanol
Idanimọ IR	Spectrum ti ayẹwo ni ibamu si ti boṣewa itọkasi
HPLC idanimọ	Akoko idaduro ti ayẹwo idanwo ni ibamu si ti boṣewa itọkasi
Akoonu Omi (nipasẹ KF)	5.5% ~ 6.5%
Specific Optical Yiyi	+24.0° si +30.0° (DMF: MeOH=1:1 C=1%) (lori ohun elo alaiwu)
Aloku lori Iginisonu	≤0.10%
Awọn nkan ti o jọmọ
Furontecavir	≤0.10%
Entecavir 1-Epimer	≤0.10%
Entecavir 3-Epimer	≤0.10%
8-Methyoxy Entecavir	≤0.10%
Entecavir 4-Epimer	≤0.10%
8-Hydroxy Entecavir	≤0.10%
4-Dimethylsilyl Entecavir	≤0.10%
Agbo ibatan Entecavir A	≤0.10%
Eyikeyi Aisọye Aimọ	≤0.10%
Lapapọ Awọn Aimọ	≤0.30%
Awọn ohun elo ti o ku
kẹmika kẹmika	≤600ppm
Dichloromethane	≤300ppm
Ethyl acetate	≤1000ppm
Tetrahydrofuran	≤720ppm
Toluene	≤890ppm
Benzyl kiloraidi	≤1000ppm
Benzyl Ọtí	≤1000ppm
Makirobia Ifilelẹ
Lapapọ Awọn iṣiro Aerobic	≤100cfu/g
Iwukara ati Molds	≤10cfu/g
Escherichia Coli	Ko yẹ ki o wa
Awọn irin Heavy	≤10ppm
Ayẹwo	98.0% ~ 102.0% (HPLC; lori ipilẹ anhydrous)
Patiku Iwon	95% ti awọn patikulu yẹ ki o wa laarin 125um
Igbeyewo Standard	Standard Enterprise;United States Pharmacopoeia (USP) Standard
Lilo	Oogun egboogi ti a lo ninu itọju Ẹdọ-arun B

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Entecavir Monohydrate (CAS 209216-23-9) jẹ oogun ajẹsara ti ẹnu ti a lo ninu itọju Iwoye Iwoye B (HBV).Entecavir Monohydrate jẹ afọwọṣe nucleoside (diẹ sii pataki, afọwọṣe guanine) ti o ṣe idiwọ transcription yiyipada, ẹda DNA ati transcription ninu vira.O jẹ iru tuntun ti cyclopentyl acyl guanosine awọn oogun ọlọjẹ Hepatitis B pẹlu awọn ipa elegbogi rẹ bii Entecavir.O ti lo ni ile-iwosan si itọju ti agbalagba Chronic Hepatitis B ninu eyiti o wa ni isodipupo gbogun ti nṣiṣe lọwọ, ti o pọ si transaminase ALT tabi awọn egbo ti nṣiṣe lọwọ ti a fihan lati itan-akọọlẹ ẹdọ.Entecavir Monohydrate jẹ apaniyan ti o lagbara ati yiyan ti HBV, pẹlu EC50 ti 3.75 nM ninu sẹẹli HepG2.Entecavir jẹ onidalẹkun transscriptase iyipada.O ṣe idilọwọ Awọn ọlọjẹ Hepatitis B (HBV) lati isodipupo ati dinku iye ọlọjẹ ninu ara.