Erlotinib Hydrochloride CAS 183319-69-9 Mimo> 99.0% (HPLC) Aworan Ifihan

Erlotinib Hydrochloride CAS 183319-69-9 Mimọ>99.0% (HPLC)

Apejuwe kukuru:

Orukọ Kemikali: Erlotinib Hydrochloride

Synonyms: Erlotinib HCl;Tarceva

CAS: 183319-69-9

Mimọ (HPLC):>99.0%

Irisi: Funfun si Paa-White Crystalline Powder

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Jẹmọ Products

ọja Tags

Apejuwe:

Olupese asiwaju ati olupese ti Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-ọkan CAS 179688-29-0
Please contact: alvin@ruifuchem.com

Kemikali Properties:

Orukọ Kemikali	Erlotinib Hydrochloride
Awọn itumọ ọrọ sisọ	Erlotinib HCl;Tarceva;CP-358774 Hydrochloride;6,7-Bis (2-methoxyethoxy) -4- (3-ethynylanilino) quinazoline Hydrochloride;N- (3-Ethynylphe nyl) [6,7-bis (2-methoxyethoxy) quinazolin-4-yl] amine HCl
Nọmba CAS	183319-69-9
NỌMBA CAT	RF-PI2242
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Fọọmu Molecular	C22H24ClN3O4
Òṣuwọn Molikula	429.90
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun lati Pa-White Crystalline Powder
Idanimọ	A: IR: Ni ibamu si Spectrum Reference B: HPLC: Ni ibamu si Reference RT
Solubility	Tiotuka pupọ diẹ ninu Omi, Isọkufẹ diẹ ni Methanol ati Iṣeṣe Insoluble ni Acetonitrile, Acetone, Ethyl Acetate ati Hexane
Ojuami Iyo	223.0 ~ 229.0 ℃
Pipadanu lori Gbigbe	<0.50%
Aloku lori Iginisonu	<0.20%
Awọn irin Heavy	<20ppm
Aimọ Kanṣoṣo	<0.50%
Lapapọ Awọn Aimọ	<1.00%
Awọn ohun elo ti o ku
Pyridine	<4000ppm
Chloroform	<4000ppm
DMF	<3000ppm
Mimọ / Analysis Ọna	> 99.0%
Aseyori / Analysis Ọna	98.5% ~ 101.0% (Ṣiṣe lori ipilẹ Anhydrous)
Igbeyewo Standard	Standard Enterprise
Lilo	API

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

FAQ:

Ohun elo:

Erlotinib Hydrochloride (CAS: 183319-69-9) jẹ moleku kekere ti awọn oludena idagbasoke ti epidermal tyrosine kinase inhibitor reversible, ti a lo ni pataki ni itọju ti agbegbe ti ilọsiwaju tabi metastatic ti kii ṣe kekere akàn ẹdọfóró sẹẹli ati laini keji tabi itọju laini mẹta ti akàn pancreatic.Erlotinib Hydrochloride ni a fọwọsi ni Oṣu kọkanla, ọdun 2004, fun itọju ilọsiwaju tabi akàn ẹdọfóró ti kii-kekere kekere.O jẹ ti kilasi kanna bi Gefitinib, quinazoline miiran ti a fọwọsi fun itọju ti akàn ẹdọfóró to ti ni ilọsiwaju, ṣugbọn pẹlu ilọsiwaju awọn ohun-ini elegbogi.Molikula naa jẹ ipilẹṣẹ nipasẹ Pfizer ati idagbasoke ti bẹrẹ ni ifowosowopo pẹlu OSI, eyiti o gba awọn ẹtọ ni kikun si oogun naa nigbati Pfizer dapọ pẹlu Warner Lambert.Lẹhinna, Genentech/Roche lọ sinu adehun iwe-aṣẹ pẹlu OSI lati ṣe agbekalẹ ati ta oogun naa ni AMẸRIKA ati Ni kariaye.Olugba ifosiwewe idagba epidermal ti a yan (EGFR) - inhibitor kinase tyrosine.Antineoplastic.Erlotinib Hydrochloride jẹ oludena HER1/EGFR pẹlu IC50 ti 2 nM.Erlotinib HCl wa bi 25-, 100-, ati 150-mg wàláà isakoso fororal.