Etravirine TMC-125 CAS 269055-15-4 Assay ≥99.0% (HPLC) API Factory High Purity
Olupese pẹlu Giga ti nw ati Idurosinsin Didara
Orukọ Kemikali: EtravirineTMC-125)
CAS: 269055-15-4
API Didara Giga, Iṣelọpọ Iṣowo
Orukọ Kemikali | Etravirine |
Awọn itumọ ọrọ sisọ | TMC-125 |
Nọmba CAS | 269055-15-4 |
NỌMBA CAT | RF-API54 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C20H15BrN6O |
Òṣuwọn Molikula | 435.28 |
iwuwo | 1,439 g / cm3 |
Sowo Ipò | Labẹ Ibaramu otutu |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun Ri to Powder |
Idanimọ | Nipasẹ IR, HPLC |
Ojuami Iyo | 211.0 ~ 216.0 ℃ |
Omi akoonu | ≤0.50% |
Aloku lori Iginisonu | ≤0.20% |
Awọn irin Heavy | ≤20ppm |
Eyikeyi Nikan Aimọ | ≤0.50% |
Lapapọ Awọn Aimọ | ≤1.0% |
Ayẹwo | ≥99.0% (HPLC) |
Igbeyewo Standard | Standard Enterprise |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Etravirine (TMC-125) (CAS 269055-15-4) jẹ iran-keji ti kii-nucleoside yiyipada transcriptase inhibitor (NNRTI) ti a lo fun itọju HIV.O jẹ itọkasi fun lilo ni apapo pẹlu awọn aṣoju antiretroviral miiran fun atọju kokoro-arun HIV-1 ni awọn alaisan agbalagba ti o ni iriri itọju ti o ni ẹri ti ẹda-ara ati awọn igara HIV-1 ti o lodi si awọn NNRTI ti o wa lọwọlọwọ ati awọn aṣoju antiretroviral miiran.Awọn NNRTIs, pẹlu nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs/NtRTIs), jẹ awọn ẹya pataki ti awọn ilana apapo ti a lo lọwọlọwọ lati ṣe itọju ikolu HIV-1.Awọn NRTIs/NtRTIs n ṣiṣẹ nipa jije pẹlu awọn sobusitireti nucleotide ti ara ti yiyipada transcriptase fun isọpọ sinu DNA gbogun ti ati ifopinsi pq atẹle.Ni iyatọ, awọn NNRTIs sopọ mọ aaye allosteric ti henensiamu ati ki o ṣe idiwọ iṣẹ DNA polymerase nipa jijẹ awọn ayipada aiṣedeede si aaye katalitiki.