Fingolimod Hydrochloride CAS 162359-56-0 Mimo ≥99.0% (HPLC) API Iwa mimọ giga
Olupese pẹlu Giga ti nw ati Idurosinsin Didara
Orukọ Kemikali: Fingolimod Hydrochloride
CAS: 162359-56-0
Fingolimod Hydrochloride jẹ oogun ti a fọwọsi FDA fun itọju Sclerosis Ọpọ.
API Didara Giga, Iṣelọpọ Iṣowo
Orukọ Kemikali | Fingolimod Hydrochloride |
Awọn itumọ ọrọ sisọ | Fingolimod HCl;FTY 720 |
Nọmba CAS | 162359-56-0 |
NỌMBA CAT | RF-API39 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
Fọọmu Molecular | C19H34ClNO2 |
Òṣuwọn Molikula | 343.93 |
Ojuami Iyo | 102.0 ~ 107.0 ° C |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Pa-White Powder |
Idanimọ | HPLC |
Ojuami Iyo | 102.0 ~ 106.0 ℃ |
Solubility | Soluble patapata ninu Omi |
Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
Ọrinrin (KF) | ≤0.50% |
Aloku lori Iginisonu | ≤0.20% |
Awọn irin Heavy | ≤20ppm |
Awọn ohun elo ti o ku | |
Dichloromethane | ≤0.05% |
Ethyl acetate | ≤0.50% |
Ethanol | ≤0.50% |
kẹmika kẹmika | ≤0.30% |
Toluene | ≤0.089% |
THF | ≤0.50% |
DMF | ≤0.088% |
Awọn nkan ibatan | |
Aimọ Kanṣoṣo | ≤0.50% |
Lapapọ Awọn Aimọ | ≤1.0% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Ohun elo elegbogi ti nṣiṣe lọwọ (API) |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti Fingolimod Hydrochloride (CAS: 162359-56-0) pẹlu didara to gaju.
Fingolimod Hydrochloride jẹ oogun akọkọ ti ẹnu fun itọju ọpọ sclerosis.O ti ni idagbasoke ni aṣeyọri nipasẹ ile-iṣẹ elegbogi Novartis, ati pe o ti fọwọsi fun tita nipasẹ Ile-iṣẹ Ounje ati Oògùn AMẸRIKA (FDA).Ọpọ sclerosis jẹ aisan aiṣan ti iṣan ti o le fa ki alaisan padanu oye ti iwọntunwọnsi, han awọn spasms iṣan ati awọn rudurudu gbigbe miiran.Fingolimod Hydrochloride jẹ oluyipada olugba sphingosine-l-phosphate (S1PR).Lẹhin phosphorylation, O ti wa ni owun lati s1P olugba ti o wa lori dada ti lymphocyte, eyi ti yoo yi lymphocyte ijira, ki o si se igbelaruge ẹyin sinu lymphatic àsopọ, ati ki o se lymphocytes lati nlọ awọn lymphoid àsopọ ati ki o gba sinu alọmọ.Nitorinaa, yoo ṣe idiwọ awọn sẹẹli wọnyi lati wọ inu eto aifọkanbalẹ aarin (CNS), eyiti o ṣaṣeyọri ipa ti ajẹsara.