Fondaparinux Sodium CAS 114870-03-0 API Aworan Ifihan

Fondaparinux soda CAS 114870-03-0 API

Apejuwe kukuru:

Orukọ Kemikali: Fondaparinux Sodium

CAS: 114870-03-0

Irisi: Funfun si Paa-White Powder

Ayẹwo: 95.0% ~ 103.0% (lori Gbẹgbẹ)

An Antithrombotic Anticoagulant, Factor Xa inhibitor

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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ọja Tags

Apejuwe:

Ipese pẹlu Iwa mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Fondaparinux Sodium
CAS: 114870-03-0
An Antithrombotic Anticoagulant, Factor Xa inhibitor
API Didara Giga, Iṣelọpọ Iṣowo

Kemikali Properties:

Orukọ Kemikali	Fondaparinux iṣuu soda
Nọmba CAS	114870-03-0
NỌMBA CAT	RF-API84
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C31H43N3O49S8.10NA
Òṣuwọn Molikula	1728.08
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun to Pa-White Powder
Aseyori / Analysis Ọna	95.0% ~ 103.0% (lori ipilẹ ti o gbẹ)
Solubility	Soluble Larọwọto ninu Omi, 2.0M Sodium Chloride ati 0.5M Sodium Hydroxide ati Insoluble ni Ethanol
Idanimọ 13C-NMR	Awọn atunṣe fun Fondaparinux Sodium yẹ ki o ṣe akiyesi ni 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, 176.7.7Awọn iyipada Kemikali ti awọn ifihan agbara wọnyi ko ni iyatọ nipasẹ diẹ ẹ sii ju ± 0.3ppm awọn ifihan agbara miiran ti awọn giga iyipada ati awọn iyipada kemikali, ti a ṣe si Fondaparinux Sodium, boya ri laarin 58.0 ~ 80.5 ppm ati 98.7 ~ 104.5ppm
HPLC idanimọ	Akoko idaduro ti oke pataki ti ojutu ayẹwo ni ibamu si ti ojutu boṣewa
AAS idanimọ	Iṣuu soda yẹ ki o ni gbigba abuda ni 330.2nm labẹ ipinnu iṣuu soda
pH	6.0 ~ 8.0
Sodium (Na)	11.5% ~ 15.0% (Iṣiro lori anhydrous ati awọn olomi-ọfẹ)
Sulfate ọfẹ	≤0.30%
Kloride to ku	≤1.00%
Awọn nkan ti o jọmọ
Aimọ́ A	≤0.80%
Aimọ́ B	≤0.60%
Nikan Miiran Aimọ	≤0.30%
Lapapọ Awọn Aimọ	≤2.00%
Awọn ohun elo ti o ku
kẹmika kẹmika	≤3000ppm
Ethanol	≤5000ppm
Ethyl acetate	≤5000ppm
DMF	≤880ppm
Methylbenzene	≤890ppm
Pyridine	≤50ppm
Akoonu Omi (KF)	≤15.0%
Awọn endotoxins kokoro arun	≤3.3EU/mg
Makirobia Ifilelẹ	Nọmba apapọ awọn microorganisms ≤100cfu/g
Igbeyewo Standard	Standard Enterprise;United States Pharmacopoeia (USP) Standard
Lilo	API, An Antithrombotic Anticoagulant, Factor Xa inhibitor

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Fondaparinux Sodium (CAS 114870-03-0) jẹ akọkọ ti kilasi tuntun ti antithrombotic anticoagulant kemikali ti o ni ibatan si awọn heparins iwuwo molikula kekere (LMWH).Fondaparinux soda jẹ ifosiwewe Xa inhibitor lati ṣe agbekalẹ aaye isọdọmọ giga fun ifosiwewe antithrombin III (ATIII) anticoagulant.Fondaparinux iṣuu soda abuda ni aaye yii ṣe agbara ipa inhibitory adayeba ti ATIII lodi si ifosiwewe Xa nipasẹ ipin kan ti o to 300, eyiti o yorisi idinamọ ti iran thrombin.O ti wa ni tita nipasẹ GlaxoSmithKline.Ẹya jeneriki ti o dagbasoke nipasẹ Alchemia ti wa ni tita laarin AMẸRIKA nipasẹ Awọn ile-iṣẹ Dokita Reddy.Fondaparinux soda ni a kọkọ ṣe afihan ni AMẸRIKA fun idena ti iṣọn-ẹjẹ iṣọn jinlẹ eyiti o le ja si iṣọn-ẹjẹ ẹdọforo lẹhin iṣẹ abẹ orthopedic pataki.Molikula sintetiki patapata yii jẹ ẹda ti ọkọọkan heparin pentasaccharide, ajẹkù ti o kuru ju ni anfani lati ṣe itusilẹ antithrombin lllmediated inhibition ti ifosiwewe Xa nitorinaa ṣe idiwọ iran thrombin laisi iṣe antithrombin.