Fulvestrant (ICI 182780) CAS 129453-61-8 API Factory Didara Giga Aworan Ifihan

Fulvestrant (ICI 182780) CAS 129453-61-8 API Didara Giga Factory

Apejuwe kukuru:

Orukọ: Fulvestrant (ICI 182780)

CAS: 129453-61-8

Irisi: Funfun si Paa-White Crystalline Powder

Ayẹwo: 97.0% ~ 102.0% (lori ipilẹ ti o gbẹ)

A lo Fulvestrant ni itọju ti akàn igbaya to ti ni ilọsiwaju ti homonu ni awọn obinrin postmenopausal.

API Didara Giga, Iṣelọpọ Iṣowo

Inquiry: alvin@ruifuchem.com

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ọja Tags

Apejuwe:

Ipese Olupese pẹlu Iwa-mimọ giga ati Didara Idurosinsin
Orukọ: Fulvestrant
CAS: 129453-61-8
A lo Fulvestrant ni itọju ti akàn igbaya to ti ni ilọsiwaju ti homonu ni awọn obinrin postmenopausal.
API Didara Giga, Iṣelọpọ Iṣowo

Kemikali Properties:

Orukọ Kemikali	Fulvestrant
Awọn itumọ ọrọ sisọ	(7α,17β) -7- [9-[(4,4,5,5,5-Pentafluorpentyl) sulfinyl] nonyl] estra-1,3,5 (10) -trien-3,17-diol;Ọdun 182780
Nọmba CAS	129453-61-8
NỌMBA CAT	RF-API81
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C32H47F5O3S
Òṣuwọn Molikula	606.77
Ojuami Iyo	104.0 ~ 106.0 ℃
Solubility	Soluble ni kẹmika, Ethanol;Ailopin ninu Omi
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun lati Pa-White Crystalline Powder
Idanimọ	Nipasẹ IR, HPLC
Specific Optical Yiyi	+ 108,0 ° to + 115,0 °
Pipadanu lori Gbigbe	≤0.50%
Aloku lori Iginisonu	≤0.10%
6-Keto-Fulvestrant	≤0.10%
6,7-Fulvestrant	≤0.10%
Fulvestrant Sulfone	≤0.20%
Fulvestrant gbooro sii	≤0.30%
Fulvestrant Sterol Dimmer	≤0.80%
Eyikeyi Olukuluku Aisọtọ Aimọ	≤0.10%
Lapapọ Awọn Aimọ	≤1.0%
Fulvestrant A	42.0% ~ 48.0%
Fulvestrant B	52.0% ~ 58.0%
DMF	≤620ppm
Awọn irin Heavy	≤10ppm
Ayẹwo	97.0% ~ 102.0% (lori ipilẹ ti o gbẹ)
Ibi ipamọ	Fipamọ ni ile itaja awọn apoti sooro ina ti o ni pipade daradara ti a fi sinu firiji ni 2 ~ 8℃
Igbeyewo Standard	United States Pharmacopoeia (USP) Standard
Lilo	Estrogen Olugba Atako

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Fulvestrant (ICI-182780) CAS 129453-61-8, jẹ oogun abẹrẹ iṣan ti o ni idagbasoke nipasẹ ile-iṣẹ AstraZeneca ati pe a lo ninu itọju ti akàn igbaya ti o ni ilọsiwaju ti homonu ni awọn obinrin postmenopausal.Fulvestrant jẹ oogun antiestrogen nikan ti o le ṣee lo ni ile-iwosan jakejado lẹhin itọju tamoxifen ti ko ni aṣeyọri.Oogun yii jẹ iru itọju ailera endocrine, nitorinaa kii yoo fa eyikeyi awọn ipa buburu ti a rii ni kimoterapi, fifun ni ibamu ibamu alaisan to dara.Awọn idanwo ile-iwosan pupọ ti rii pe 250mg Fulvestrant jẹ doko ati ailewu nigbagbogbo bi ila keji ti itọju fun akàn igbaya to ti ni ilọsiwaju.Fulvestrant jẹ Olugba Estrogen Olugba (ER) sintetiki pẹlu IC50 ti 0.94 nM ni ayẹwo-ọfẹ sẹẹli kan.Fulvestrant tun nfa autophagy ati apoptosis ati pe o ni iṣẹ antitumor.