Glimepiride CAS 93479-97-1 Assay 98.0% ~ 102.0% API Iwa mimọ giga
Ipese pẹlu Iwa mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Glimepiride
CAS: 93479-97-1
Glimepiride ni itọju ti Noninsulin-Igbẹkẹle Iru 2 Àtọgbẹ mellitus
API Didara Giga, Iṣelọpọ Iṣowo
Orukọ Kemikali | Glimepiride |
Awọn itumọ ọrọ sisọ | Amaryl |
Nọmba CAS | 93479-97-1 |
NỌMBA CAT | RF-API24 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C24H34N4O5S |
Òṣuwọn Molikula | 490.62 |
Ojuami Iyo | 212.2 ~ 214.5 ℃ |
Sowo Ipò | Labẹ Ibaramu otutu |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun tabi Fere Funfun Powder |
Idanimọ | IR (Ti o jọra si Standard) |
Awọn nkan ti o jọmọ | |
Cis-Isomer (A) | ≤0.80% |
Sulfonamide (B) | ≤0.40% |
Urethane (C) | ≤0.10% |
3-Isomer (D) | ≤0.20% |
Eyikeyi Iwa Aimọ | ≤0.10% |
Lapapọ Awọn Aimọ | ≤0.50% |
Pipadanu lori Gbigbe | ≤0.50% |
Aloku lori Iginisonu | ≤0.10% |
Awọn irin Heavy | ≤0.001% |
Ayẹwo | 98.0% ~ 102.0% |
Igbeyewo Standard | European Pharmacopeia (EP);Orilẹ Amẹrika Pharmacopoeia (USP) |
Lilo | Ohun elo elegbogi ti nṣiṣe lọwọ (API) |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti Glimepiride (CAS: 93479-97-1) pẹlu didara to gaju, eroja elegbogi ti nṣiṣe lọwọ (API).Glimepiride jẹ oogun apakokoro ti o ṣe iranlọwọ lati ṣakoso awọn ipele suga ẹjẹ.Glimepiride jẹ iṣẹ ṣiṣe pipẹ, sulfonylurea iran-kẹta pẹlu iṣẹ ṣiṣe hypoglycemic.
Glimepiride (orukọ iṣowo akọkọ Amaryl) jẹ oogun oogun antidiabetic sulfonylurea ti o wa ni aarin-si-gun.Gẹgẹbi gbogbo sulfonylureas, glimepiride n ṣiṣẹ bi aṣiri insulini.O dinku suga ẹjẹ nipasẹ safikun itusilẹ ti hisulini lati awọn sẹẹli beta pancreatic ti n ṣiṣẹ ati nipa jijẹ ifamọ ti awọn sẹẹli agbeegbe si hisulini.Glimepiride ṣee ṣe sopọ mọ awọn olugba potasiomu ti o ni ifaramọ ATP lori dada sẹẹli pancreatic, idinku iṣesi potasiomu ati nfa depolarization ti awọ ara.Depolarization Membrane n ṣe influx kalisiomu ion nipasẹ awọn ikanni kalisiomu ti o ni imọlara foliteji.Ilọsoke ninu ifọkansi ion kalisiomu intracellular jẹ ki yomijade ti hisulini.A lo Glimepiride ni akọkọ lati tọju awọn alaisan ti o ni àtọgbẹ iru 2 ati pe o tun le dinku awọn aye ti ẹnikan yoo dagbasoke awọn ilolu ti àtọgbẹ iru 2.Oogun naa jẹ ifọwọsi nipasẹ FDA ni ọdun 1995 ati pe o jẹ iṣelọpọ nipasẹ Sanofi-Aventis.O le ṣee lo pẹlu ounjẹ to dara ati eto idaraya ati pe o tun le ṣee lo nikan tabi pẹlu awọn oogun antidiabetic miiran ti o ba nilo.Glimepiride le ṣee lo boya bi monotherapy tabi ni apapo pẹlu hisulini.