Guanfacine Hydrochloride Guanfacine HCl CAS 29110-48-3 API USP Standard High Purity
Olupese pẹlu Giga ti nw ati Idurosinsin Didara
Orukọ Kemikali: Guanfacine Hydrochloride
Synonyms: Guanfacine HCl
CAS: 29110-48-3
Guanfacine Hydrochloride jẹ agonist α2A-adrenoceptor ti o yan.Antihypertensive
API Didara Giga, Iṣelọpọ Iṣowo
Orukọ Kemikali | Guanfacine Hydrochloride |
Awọn itumọ ọrọ sisọ | Guanfacine HCl |
Nọmba CAS | 29110-48-3 |
NỌMBA CAT | RF-API40 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C9H10Cl3N3O |
Òṣuwọn Molikula | 282.55 |
Ojuami Iyo | 211.0 ~ 215.0 ℃ |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun lati Pa-White Crystalline Powder |
Idanimọ | Gbigba infurarẹẹdi;HPLC |
Pipadanu lori Gbigbe | ≤0.50% |
Aloku lori Iginisonu | ≤0.10% |
Awọn irin Heavy | ≤20ppm |
Ayẹwo | 98.0% ~ 102.0% (HPLC lori ipilẹ gbigbẹ) |
Chromatographic Mimọ | ≥99.0% |
Igbeyewo Standard | USP Standard |
Lilo | Ohun elo elegbogi ti nṣiṣe lọwọ (API) |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti Guanfacine Hydrochloride (CAS: 29110-48-3) pẹlu didara to gaju.
Guanfacine hydrochloride ti n ṣiṣẹ ni aarin agonist a-adrenoceptor.Antihypertensive.Guanfacine hydrochloride, aṣoju egboogi-hypertensive, jẹ agonist α2A-adrenoceptor ti o yan pẹlu Kd ti 31 nM ati ṣafihan yiyan-agbo 60 lori α2B-adrenoceptors.Guanfacine dinku systolic mejeeji ati titẹ ẹjẹ diastolic nipa mimuuṣiṣẹpọ eto aifọkanbalẹ aarin α2A norẹpinẹpirini autoreceptors, eyiti o mu abajade iyọnu ti agbeegbe dinku ati nitorinaa idinku ninu ohun orin ibanujẹ agbeegbe.Awọn ohun elo itọju ailera fun guanfacine jẹ iru si awọn ti awọn agonists α2-adrenergic miiran ti aarin ati methyldopa.O ti munadoko bi monotherapy ni itọju awọn alaisan ti o ni haipatensonu kekere si iwọntunwọnsi.