H-Gly-OMe·HCl CAS 5680-79-5 Glycine Methyl Ester Hydrochloride Assay>99.0%

1. Awọn ohun-ini: Ọja yii yẹ ki o jẹ funfun crystalline lulú.
2. Ayẹwo:
1) Ipinnu ti Glycine Methyl Ester Hydrochloride assay
1.1 ọna
Labẹ awọn ipo ekikan, ayẹwo naa ṣe pẹlu iye kan ti iyọ fadaka, ati iyọkuro fadaka ti o pọ ju ti wa ni yi pada pẹlu ammonium thiocyanate, tọka si ammonium ferric sulfate.
Gẹgẹbi itọkasi, akoonu chlorine lapapọ ni a pinnu ni ibamu si iwọn iwọn ojutu boṣewa ti o jẹ, ati pe akoonu chlorine lapapọ ti yọkuro lati inu akoonu ti glycine hydrochloride lati gba akoonu Glycine Methyl Ester Hydrochloride.
1.2 Reagents
Dibutyl phthalate;
Ojutu acid nitric: 2+3;
Ojutu titrate boṣewa fadaka: c(AgNO3) = 0.1 mol/L
Ammonium thiocyanate ojutu titration boṣewa: c(NH4SCN) = 0.1 mol/L
Ammonium ferric sulfate (III) olomi itọka: 80 g/L
1.3 Ilana Onínọmbà
Ṣe iwọn nipa apẹẹrẹ 0.5g, deede si 0.0001g.Fi sinu ọpọn conical 250ml kan, tu ni omi 40ml, ṣafikun ojutu nitric acid 10 milimita, Fikun (50 ± 0.02) milimita fadaka iyọdi ojutu titration, 3mL ammonium ferric sulfate Atọka ojutu, 4mL dibutyl phthalate, ati ojutu thiocyanate Ammonium jẹ ojutu boṣewa titration. titrated titi ti ojutu je ina brown ati ki o wà colorless fun 30 s.
1.4 Abajade isiro
Idapọpọ ti akoonu glycine methyl ester hydrochloric acid w1, eyiti a fihan bi%, jẹ iṣiro ni ibamu si Idogba (1):
w1= (c1V1-c2V2)*M/1000/m * 100-w2 *1.126 agbekalẹ (1)
Nibo:
V1: Iwọn didun ti fadaka iyọti boṣewa ojutu titration (milimita)
V2: Iwọn didun ti ammonium thiocyanate ojutu titration boṣewa ti o jẹ nipasẹ titration (milimita)
c1: Iye gangan ti ojutu titrate boṣewa ti fadaka (mol/L)
c2: Iye gangan ti ojutu titration boṣewa ammonium thiocyanate (mol/L)
w2: Ibi ida (%) ti akoonu glycine hydrochloride gẹgẹbi a ti pinnu ni Abala 4.2
M: Iwọn Molar ti glycine methyl ester hydrochloride (g/mol)
1.126: Olusọdipúpọ iyipada ti glycine hydrochloride si Glycine methyl ester hydrochloride.
Iwọn itumọ iṣiro ti awọn abajade wiwọn afiwe meji ni a mu bi abajade wiwọn, ati pe iyatọ pipe laarin awọn abajade wiwọn afiwera meji ko ju 0.05%.
2) Ipinnu ti glycine hydrochloride akoonu
2.1 ọna
Lilo dimethyl ofeefee bi olutọka, ayẹwo naa jẹ titrated pẹlu iṣuu soda hydroxide boṣewa titrating ojutu, ati pe iwọn didun ojutu naa jẹ titọ ni ibamu si agbara boṣewa iṣuu soda hydroxide.
Ṣe iṣiro akoonu glycine hydrochloride.
2.2 Reagent
Ojutu titration boṣewa ti iṣuu soda hydroxide: c (NaOH) = 0.1mol/L
Dimethyl ofeefee itọkasi omi: 10 g/L
2.3 Ilana Itupalẹ
Ṣe iwọn nipa 5.0 g ayẹwo yàrá, deede si 0.0001g, sinu beaker 200 milimita, tu pẹlu omi 50ml, ki o si fi 5 silė ti dimethyl
Omi itọka ofeefee, pẹlu iṣuu soda hydroxide boṣewa titration ojutu titration titi ojutu lati pupa si ofeefee osan jẹ aaye ipari
2.4 Abajade Isiro
Apapọ ida w2 ti akoonu glycine hydrochloride jẹ afihan bi% ati iṣiro ni ibamu si Idogba (2):
w2 = (V/1000) cM/m *100 agbekalẹ (2)
Nibo:
V: Iwọn didun iṣuu soda hydroxide ojutu titration boṣewa (ml)
c: Iye gangan ti iṣuu soda hydroxide boṣewa titration ojutu ifọkansi (mol/L)
M: Iwọn Molar ti glycine hydrochloride (g/mol)
m: Iwọn titobi ti ayẹwo (g)
Iwọn itumọ iṣiro ti awọn abajade wiwọn afiwe meji ni a mu bi abajade wiwọn, ati pe iyatọ pipe laarin awọn abajade wiwọn afiwera meji ko ju 0.05% lọ.
3. Idoti yo: Ni ibamu si ọna ti ipinnu aaye yo (Chinese Pharmacopoeia 2010 Appendix VIC), aaye ibiti o ti yo jẹ 172-178 ºC.
4. Gbígbẹ àdánù làìpẹ: ya ọja yi ni 105.0 ℃ ati ki o gbẹ o si ibakan àdánù.Pipadanu iwuwo kii yoo kọja 0.5%.
5. Ibi ipamọ: Ọja yi yẹ ki o wa ni firiji kuro lati ina.