HBTU CAS 94790-37-1 Peptide Coupling Reagent Purity>99.0% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti HBTU (CAS: 94790-37-1) pẹlu didara to gaju.Kemikali Ruifu n pese lẹsẹsẹ ti awọn reagents aabo ati awọn isọdọkan.Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, kekere ati awọn iwọn olopobobo ti o wa.Ra HBTU,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | HBTU |
Awọn itumọ ọrọ sisọ | 1-[Bis (dimethylamino) methylene] -1H-benzotriazolium 3-Oxide Hexafluorophosphate;N, N, N', N'-Tetramethyl-O- (1H-Benzotriazol-1-yl) uronium Hexafluorophosphate;O-Benzotriazole-N, N, N', N'-Tetramethyluronium-Hexafluorophosphate;O- (1H-Benzotriazol-1-yl) -N, N, N', N'-Tetramethyluronium Hexafluorophosphate;2- (1H-Benzotriazole-1-yl) -1,1,3,3-Tetramethyluronium Hexafluorophosphate |
Iṣura Ipo | Ninu Iṣura, Iwọn Iṣowo |
Nọmba CAS | 94790-37-1 |
Ilana molikula | C11H16F6N5OP |
Òṣuwọn Molikula | 379,25 g / mol |
Ojuami Iyo | ≥200℃ |
iwuwo | 1.5095 |
Ni imọlara | Imọlẹ Imọlẹ, Imọra Ọrinrin |
Omi Solubility | Ailesolusan ninu Omi |
Solubility | Soluble ni Acetonitrile.Tiotuka diẹ ni Acetone, Ethanol |
Ibi ipamọ otutu. | Itura & Ibi Gbẹ (2 ~ 8℃) |
COA & MSDS | Wa |
Ẹka | Awọn Reagents Apapo |
Brand | Ruifu Kemikali |
Awọn nkan | Ayewo Standards | Awọn abajade |
Ifarahan | Funfun Crystalline Powder | Ibamu |
Ojuami Iyo | ≥200℃ | 205.6 ℃ |
Pipadanu lori Gbigbe | <0.50% | 0.11% |
Mimọ / Analysis Ọna | > 99.0% (HPLC) | 99.9% |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto | Ibamu |
NMR julọ.Oniranran 1H | Ni ibamu si Eto | Ibamu |
Fluorine NMR julọ.Oniranran | Ni ibamu si Eto | Ibamu |
Idanwo Solubility ni Acetonitrile | 1g ninu 10ml Acetonitrile Ko Solusan | Kọja |
Ipari | Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti edidi ni itura ati ki o gbẹ (2 ~ 8℃) ile itaja kuro lati awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
1. Awọn ohun-ini: Ọja yii yẹ ki o jẹ funfun crystalline lulú.
2. Ipinnu akoonu: gẹgẹbi iṣẹ-giga chromatography omi (Chinese Pharmacopoeia 2010 àtúnse Àfikún VI D) ipinnu.
Awọn ipo Chromatographic: Gel siliki ti o ni asopọ octadecylsilane ni a lo bi kikun, (250 * 4.6mm * 5.0μm);Acetonitrile: omi = 15: 85 (pH ti a ṣe atunṣe nipasẹ acetic acid = 2.5) gẹgẹbi alakoso alagbeka;Gigun wiwa jẹ 258nm.Iwọn sisan: 0.5ml/min;Nọmba ti awọn awo imọ-jinlẹ ni ibamu si HBTU
Oke akọkọ yẹ ki o ṣe iṣiro ko kere ju 2000.
Ọna ipinnu: Mu iye ti o yẹ fun ọja yii, ṣe ojutu alakoso alagbeka ti o ni HBTU 20μg fun 1 milimita, bi ojutu idanwo naa.10 μL ti ojutu idanwo ni abẹrẹ sinu chromatograph ati lẹmeji akoko idaduro ti oke paati akọkọ ni a gbasilẹ.
Awọn abajade: Gẹgẹbi ọna deede agbegbe, akoonu HBTU ko yẹ ki o kere ju 99.0%.
3. Iyọkuro ojuami: ni ibamu si ọna ipinnu aaye yo (Afikun VIIC ti Kannada Pharmacopoeia 2010 àtúnse), oṣuwọn alapapo jẹ 3 ℃ / min.
Ojuami yo ti ọja yii ko kere ju 200.0 ℃.
4. Pipadanu lori gbigbe: mu ọja yii lọ si 80 ℃ ati ki o gbẹ labẹ titẹ ti o dinku fun awọn wakati 4 si iwuwo igbagbogbo, ati pe pipadanu iwuwo ko yẹ ki o kọja 0.50%.
5. Itọkasi ti ojutu: mu 1g ti ọja yii, fi 10ml ti acetonitrile, gbigbọn daradara, ojutu yẹ ki o jẹ kedere ati gbangba.
6. Ibi ipamọ: Fipamọ sinu dudu ati ibi gbigbẹ tutu (2 ~ 8 ℃).
7. Akoko atunyẹwo: ọdun kan.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Awọn koodu ewu
R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara.
R20/21/22 - Ipalara nipasẹ ifasimu, ni olubasọrọ pẹlu awọ ara ati ti o ba gbe.
R42/43 - Le fa ifamọ nipasẹ ifasimu ati olubasọrọ ara.
Apejuwe Abo
S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun.
S36/37/39 - Wọ aṣọ aabo to dara, awọn ibọwọ ati aabo oju / oju.
S36 - Wọ aṣọ aabo to dara.
S22 - Maṣe simi eruku.
WGK Germany 3
FLUKA BRAND F CODES 8-10-21
HS koodu 2933990099
Akọsilẹ ewu Irritant
Majele LD50 ẹnu ni Ehoro:> 2000 mg/kg
HBTU (CAS: 94790-37-1) jẹ reagenti idapọ ti a lo ninu iṣelọpọ peptide.HBTU ti ṣe afihan lati dinku imunadoko-ije.
HBTU jẹ reagenti idapọ ti o wọpọ ti a lo ni iṣelọpọ peptide alakoso to lagbara.HBTU tun ti jẹ lilo ni boṣewa Fmoc ti o da lori ipilẹ-ara-ara peptide synthesis (SPPS).
HBTU, lẹhin iṣafihan ni ọdun 1978, aṣoju HBTU ṣe afihan gbaye-gbale ni kemistri ati lilo ile-iṣẹ nitori awọn ohun-ini mimuuṣiṣẹ kekere rẹ.pẹlupẹlu, o tun fihan resistance lodi si racemization.kekere ifarahan fun racemization ni a bọtini ibeere fun peptide kolaginni.ni pataki fun iṣelọpọ peptide alakoso to lagbara, awọn eso pipo pẹlu awọn akoko ifasẹyin kukuru jẹ pataki lati jẹ ki iṣelọpọ ti awọn peptides nla ṣeeṣe.
Awọn ijinlẹ aipẹ fihan pe kirisita bakanna bi ọna ojutu ti aṣoju asopọpọ yii jẹ guanidinium N-oxide kii ṣe agbo-ara uronium;Reagent idapọ fun iṣelọpọ peptide;Awọn anfani jẹ: isọdi-ije kekere pupọ, awọn ipo iṣesi ti o rọrun, akoko ifasilẹ kukuru pupọ, ati awọn eso giga.
Ṣiṣepọ Peptide da lori lilo daradara ati ailewu awọn isọdọkan.A fihan HBTU lati yi awọn acids carboxylic pada si awọn azides daradara ati adaṣe.Ilana naa le ṣee lo si ọpọlọpọ awọn acids carboxylic pẹlu awọn amino acid ti o ni idaabobo n.ni afikun, HBTU jẹ iye nla ni iṣelọpọ ọkan-ikoko ti awọn esters dipeptidyl urea, ureas, ati carbamates lati awọn acids.Awọn anfani ti HBTU pẹlu awọn aaye wọnyi: 1) ti kii ṣe ibẹjadi ati nitorina o dara julọ fun iṣelọpọ peptide alakoso ojutu / ri to lagbara.2) solubility giga ati iduroṣinṣin ni awọn olomi kilasika.3) ṣee ṣe fun ibojuwo ifaseyin awọ.