Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Mimọ>99.0% (HPLC)
Orukọ Kemikali | 3- (4-Phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-4-amine |
Awọn itumọ ọrọ sisọ | Ibrutinib intermeidate N-2;Ibrutinib Deacryloylpiperidine;Ibrutinib Aimọ 8;5- (4-Phenoxyphenyl) -7H-pyrrolo [2,3-d] pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl Aimọ |
Nọmba CAS | 330786-24-8 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C17H13N5O |
Òṣuwọn Molikula | 303.32 |
Ojuami Iyo | > 262 ℃ (oṣu kejila) |
iwuwo | 1.380 ± 0,06 g / cm3 |
Kíláàsì ewu | 6.1;Majele |
Iṣakojọpọ Ẹgbẹ | III |
COA & MSDS | Wa |
Ipilẹṣẹ | Shanghai, China |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Pa-White to Khaki Powder |
Idanimọ | HNMR, LC-MS |
Mimọ / Analysis Ọna | > 99.0% (HPLC) |
Pipadanu lori Gbigbe | <1.00% |
Nikan Max.Aimọ | <1.00% |
Lapapọ Awọn Aimọ | <1.00% |
Awọn irin Heavy (gẹgẹbi Pb) | <20ppm |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti Ibrutinib (CAS: 936563-96-1) |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
3- (4-Phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-4-amine (CAS: 330786-24-8) jẹ agbedemeji sintetiki ti o wulo ni iṣelọpọ ti Ibrutinib (CAS: 936563-96-1). ).Ibrutinib jẹ iru ti Bruton tyrosine kinase (BTK) onidalẹkun, o le ṣee lo fun awọn itọju ti onibaje lymphocytic aisan lukimia (CLL) ati mantle cell lymphoma (MCL).MCL ati CLL jẹ ti sẹẹli B-cell ti kii-Hodgkin's lymphoma, eyiti o nira lati ṣe iwosan ati rọrun lati loorekoore.Ajẹsara kemikali ti o wọpọ ko ni ibi-afẹde, nigbagbogbo waye 3 tabi 4 awọn aati ikolu.Ibrutinib ati B lymphocytes le ṣe ifọkansi pẹlu BTK eyiti o jẹ dandan fun dida, iyatọ, ati gbigbe alaye, ṣe idiwọ iṣẹ BTK ni aibikita, ati ṣe idiwọ itankale sẹẹli tumo ati iwalaaye daradara.Ibrutinib le gba ni kiakia lẹhin iṣakoso ẹnu, lakoko 1 ~ 2h de ọdọ ifọkansi ẹjẹ ti o pọju, awọn aati ikolu jẹ ti ọkan tabi meji, nitorinaa, Ibrutinib yoo di yiyan ti itọju CLL ati MCL tuntun.