N- (2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl) pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity
Ipese Iṣowo Imatinib Mesylate ati Awọn agbedemeji ti o jọmọ:
Imatinib Mesylate CAS: 220127-57-1
N- (2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl) pyrimidin-2-amine CAS: 152460-09-8
N- (5-Amino-2-methylphenyl) -4- (3-pyridyl) -2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl)methyl] benzoic acid dihydrochloride CAS: 106261-49-8
Orukọ Kemikali | N- (2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl) pyrimidin-2-amine |
Awọn itumọ ọrọ sisọ | Imatinib Mesylate Intermediate;2- (2-Methyl-5-nitroanilino) -4- (3-pyridyl) pyrimidine |
Nọmba CAS | 152460-09-8 |
NỌMBA CAT | RF-PI228 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C16H13N5O2 |
Òṣuwọn Molikula | 307.31 |
Ojuami Iyo | 188.0 ~ 193.0 ℃ |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Yellow tabi Fere Yellow Powder |
Mimo | ≥98.0% (HPLC) |
Ọrinrin (KF) | ≤0.50% |
Lapapọ Awọn Aimọ | ≤2.0% |
O pọju Nikan Aimọ | ≤1.0% |
Aloku lori iginisonu | ≤0.50% |
Awọn Irin Eru | ≤20ppm |
Igbeyewo Standard | Standard Enterprise |
Lilo | Laarin Imatinib Mesylate (CAS: 220127-57-1) |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine (CAS: 152460-09-8) pẹlu ga didara.O jẹ agbedemeji deede ni iṣelọpọ ti Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate jẹ moleku kekere ti o ṣe idiwọ c-Abl protein-tyrosine kinase, Ni pato pataki fun BCR-ABL, enzymu ti o ni nkan ṣe pẹlu aisan lukimia myelogenous onibaje (CML) ati awọn iru kan ti aisan lukimia lymphoblastic nla (GBOGBO).Iṣẹlẹ iyipada laarin awọn krómósómù 9 ati 22 ṣe ipilẹṣẹ chromosome Philadelphia, eyiti o ṣe agbejade amuaradagba idapọ Bcr-Ab pẹlu iṣẹ ṣiṣe aberrant kinase ti o ṣe agbega isọdi sẹẹli ni iyara.Imatinib Mesylate ṣe asopọ kinase pataki yii, o dẹkun idagba ti o ni ibatan CML.Imatinib Mesylate ti ṣafihan siwaju lati ṣe idiwọ PDGFR ati awọn kinases tyrosine ti o ni nkan ṣe pẹlu c-Kit.Awọn agbekalẹ ti o ni Imatinib Mesylate ni a ti lo ninu itọju awọn aarun oriṣiriṣi.