N- (2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl) pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

Apejuwe kukuru:

N- (2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl) pyrimidin-2-amine

CAS: 152460-09-8

Irisi: Yellow tabi Fere Yellow Powder

Mimọ: ≥98.0% (HPLC)

Aarin Imatinib Mesylate (CAS: 220127-57-1) ni itọju Philadelphia Chromosome-Rere Chronic Myeloid Leukemia (Ph + CML)

Didara to gaju, iṣelọpọ Iṣowo

Inquiry: alvin@ruifuchem.com


Alaye ọja

Jẹmọ Products

ọja Tags

Apejuwe:

Kemikali Properties:

Orukọ Kemikali N- (2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl) pyrimidin-2-amine
Awọn itumọ ọrọ sisọ Imatinib Mesylate Intermediate;2- (2-Methyl-5-nitroanilino) -4- (3-pyridyl) pyrimidine
Nọmba CAS 152460-09-8
NỌMBA CAT RF-PI228
Iṣura Ipo Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Fọọmu Molecular C16H13N5O2
Òṣuwọn Molikula 307.31
Ojuami Iyo 188.0 ~ 193.0 ℃
Brand Ruifu Kemikali

Awọn pato:

Nkan Awọn pato
Ifarahan Yellow tabi Fere Yellow Powder
Mimo ≥98.0% (HPLC)
Ọrinrin (KF) ≤0.50%
Lapapọ Awọn Aimọ ≤2.0%
O pọju Nikan Aimọ ≤1.0%
Aloku lori iginisonu ≤0.50%
Awọn Irin Eru ≤20ppm
Igbeyewo Standard Standard Enterprise
Lilo Laarin Imatinib Mesylate (CAS: 220127-57-1)

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

1

FAQ:

Ohun elo:

Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine (CAS: 152460-09-8) pẹlu ga didara.O jẹ agbedemeji deede ni iṣelọpọ ti Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate jẹ moleku kekere ti o ṣe idiwọ c-Abl protein-tyrosine kinase, Ni pato pataki fun BCR-ABL, enzymu ti o ni nkan ṣe pẹlu aisan lukimia myelogenous onibaje (CML) ati awọn iru kan ti aisan lukimia lymphoblastic nla (GBOGBO).Iṣẹlẹ iyipada laarin awọn krómósómù 9 ati 22 ṣe ipilẹṣẹ chromosome Philadelphia, eyiti o ṣe agbejade amuaradagba idapọ Bcr-Ab pẹlu iṣẹ ṣiṣe aberrant kinase ti o ṣe agbega isọdi sẹẹli ni iyara.Imatinib Mesylate ṣe asopọ kinase pataki yii, o dẹkun idagba ti o ni ibatan CML.Imatinib Mesylate ti ṣafihan siwaju lati ṣe idiwọ PDGFR ati awọn kinases tyrosine ti o ni nkan ṣe pẹlu c-Kit.Awọn agbekalẹ ti o ni Imatinib Mesylate ni a ti lo ninu itọju awọn aarun oriṣiriṣi.

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