Irbesartan CAS 138402-11-6 Mimo>99.0% (HPLC) API Factory Antihypertensive
Ipese Olupese, Iwa-mimọ giga, Iṣelọpọ Iṣowo
| Orukọ Kemikali | Irbesartan |
| Awọn itumọ ọrọ sisọ | BMS-186295;SR-47436;Aprovel;Avapro;2-Butyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro [4.4] kii-1-en- 4-ọkan;2-Butyl-3-[[4-[2- (2H-tetrazol-5-yl) phenyl] phenyl] methyl] -1,3-diazaspiro [4.4] kii-1-en-4-ọkan |
| Nọmba CAS | 138402-11-6 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C25H28N6O |
| Òṣuwọn Molikula | 428.54 |
| iwuwo | 1,30 ± 0,10 g / cm3 |
| Solubility ninu Omi | Ailopin ninu Omi |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Iwa | Funfun si Paa-White Crystalline Powder, Diẹ tiotuka ninu oti ati ni methylene kiloraidi, ni iṣe ti ko ṣee ṣe ninu omi |
| Gbigba Infurarẹẹdi idanimọ | Awọn IR julọ.Oniranran wa ni ibamu pẹlu awọn julọ.Oniranran gba pẹlu Irbesartan RS |
| Idanimọ 2 | Akoko idaduro ti tente oke pataki ninu chromatogram ti idanwo naa ni ibamu si Irbesartan RS |
| Mimọ / Analysis Ọna | > 99.5% (HPLC) |
| Omi | <0.50% |
| Awọn irin Heavy | <0.002% |
| Aloku lori Iginisonu | <0.10% |
| Awọn nkan ti o jọmọ | (Nipasẹ HPLC) |
| USP aimọ A | <0.20% |
| Eyikeyi Aimọ Aimọ | <0.10% |
| Lapapọ Awọn Aimọ | <0.50% |
| Organic VolatileImpurities | Pade awọn ibeere ti USP |
| Azide ti o ku | <10ppm |
| Awọn ohun elo ti o ku | (Nipasẹ GC) |
| Ethanol | <5000ppm |
| Toluene | <890ppm |
| Dichloromethane | <3000ppm |
| N, N-Dimethylformamide | <880ppm |
| T-Butyl Methyl Eteri | <5000ppm |
| Ayẹwo | 98.0 ~ 102.0% (iṣiro lori ipilẹ anhydrous) |
| Igbeyewo Standard | Standard Enterprise;USP Standard |
| Lilo | API;Antihypertensive;Fun itọju haipatensonu |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Irbesartan (CAS: C) jẹ antagonist olugba olugba angiotensin II ti a lo ni pataki fun itọju haipatensonu.Irbesartan jẹ idagbasoke nipasẹ Sanofi Iwadi (bayi apakan ti Sanofi-Aventis).O jẹ tita ni apapọ nipasẹ Sanofi-Aventis ati Bristol-Myers Squibb labẹ awọn orukọ iṣowo Aprovel, Karvea, ati Avapro.Irbesartan ni a lo lati ṣe itọju titẹ ẹjẹ giga.Avapro ti ṣe ifilọlẹ ni Germany, UK ati AMẸRIKA fun haipatensonu.Gẹgẹbi gbogbo awọn antagonists olugba angiotensin II, irbesartan jẹ itọkasi fun itọju haipatensonu.Irbesartan tun le ṣe idaduro ilọsiwaju ti nephropathy dayabetik ati pe o tun jẹ itọkasi fun idinku lilọsiwaju arun kidirin ni awọn alaisan ti o ni àtọgbẹ iru 2, haipatensonu ati microalbuminuria (> 30 mg / wakati 24) tabi proteinuria.Irbesartan tun le dinku atunṣe itanna ti myocardium, nitorinaa dinku oṣuwọn iku ti awọn alaisan ti o ni haipatensonu, o jẹ oogun ti o munadoko julọ fun itọju haipatensonu ati arun inu ọkan ati ẹjẹ.
