Ketorolac CAS 74103-06-3 Mimọ> 98.5% (HPLC)
Shanghai Ruifu Chemical Co., Ltd jẹ olupese ti Ketorolac (CAS: 74103-06-3) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, kekere ati awọn iwọn olopobobo ti o wa.Ra Ketorolac,Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | Ketorolac |
| Awọn itumọ ọrọ sisọ | 5-Benzoyl-2,3-Dihydro-1H-Pyrrolizine-1-Carboxylic Acid;5-Benzoyl-2,3-Dihydro-1h-Pyrrolo [1,2-a] pyrrole-1-Carboxylic Acid;(±) - Ketorolac;Acular LS;Keromini;rac Ketorolac;Toradol |
| Iṣura Ipo | O wa |
| Nọmba CAS | 74103-06-3 |
| Fọọmu Molecular | C15H13NO3 |
| Òṣuwọn Molikula | 255,27 g / mol |
| Ojuami Iyo | 159.0 ~ 161.0 ℃ |
| iwuwo | 1,33 ± 0,10 g / cm3 |
| Ibi ipamọ otutu. | Itura & Ibi Gbẹ (2 ~ 8℃) |
| COA & MSDS | Wa |
| Brand | Ruifu Kemikali |
| Awọn nkan | Ayewo Standards | Esi |
| Ifarahan | Pa-White Crystalline Powder | Ibamu |
| Ojuami Iyo | 159.0 ~ 161.0 ℃ | 159.5 ℃ |
| Pipadanu lori Gbigbe | <0.50% | 0.2% |
| Aloku lori Iginisonu | <0.10% | 0.062% |
| O pọju.Aimọ Kanṣoṣo | <1.00% | 0.48% |
| Awọn irin Heavy (gẹgẹbi Pb) | ≤10ppm | 6ppm |
| Mimọ / Analysis Ọna | > 98.5% (HPLC) | 99.0% |
| Proton NMR julọ.Oniranran | Ni ibamu si Eto | Ibamu |
| Ipari | Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato | |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Tọju ni wiwọ titi eiyan.Fipamọ sinu itura, gbigbẹ (2 ~ 8℃) ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
RIDADR 3249
Ewu Kilasi 6.1(a)
PackingGroup II
HS koodu 2933998090
Majele LD50 ẹnu ninu awọn eku: ~200 mg/kg (Rooks)
Ketorolac (CAS: 74103-06-3) jẹ analgesic sitẹriọdu ti kii ṣe sitẹriọdu ati oogun egboogi-iredodo, itọsẹ ti pyrrolidone. Ilana kemikali ati iṣe oogun jẹ iru si Tolectin, Zoaesthetic acid ati Indometacin.Nipa idinamọ cyclooxygenase, o ṣe idiwọ iṣelọpọ ati itusilẹ ti awọn prostaglandins, o si ṣe awọn ipa-egbogi-iredodo.O le dinku iwọn otutu ti o fa nipasẹ orisun ooru, eyiti o ni ibatan si idinamọ ti iṣelọpọ ti prostaglandin ninu eto aifọkanbalẹ aarin.O ni analgesic ti o lagbara ati iwọntunwọnsi egboogi-iredodo antipyretic ati idinamọ ti akojọpọ platelet, ati pe ko ni idinamọ ti isunmi ati afẹsodi.Ninu awọn adanwo ẹranko, ipa analgesic ni okun sii ju aspirin, indomethacin ati naproxen. O jẹ dọgba tabi dara julọ ju ipa-iredodo ti naproxen ati indomethacin, phenylbutazone, ipa antipyretic rẹ lori awọn eku lagbara ju aspirin ati phenylbutazone ati kanna pẹlu indomethacin ati naproxen.O ṣe idiwọ akojọpọ platelet ti o fa nipasẹ arachidonic acid ati collagen.Ṣugbọn ko ṣe idiwọ ifakalẹ ti adenosine diphosphate (ADP).Ọja yii ni kiakia ati ki o gba patapata lẹhin abẹrẹ intramuscular, ati pe o fẹrẹ gba patapata lẹhin iṣakoso ẹnu.Ounjẹ le fa fifalẹ iyara gbigba, ṣugbọn ko ni ipa lori iwọn gbigba, ati pe bioavailability jẹ 80% ~ 100%.Awọn iṣẹju 10 lẹhin abẹrẹ intramuscular ti 30mg, o maa n yọ irora naa kuro ni gbangba.Lẹhin awọn iṣẹju 50, tente oke ti ifọkansi pilasima jẹ to 2.2 g / milimita.Lẹhin awọn iṣẹju 30 ~ 60 ti iṣakoso ẹnu, irora naa han gbangba ati ifọkansi ti pilasima jẹ tente oke ni awọn wakati 1.5 si 4.Igbesi aye idaji pilasima ti awọn ọdọ jẹ nipa awọn wakati 5.3, ati fun awọn agbalagba o jẹ nipa awọn wakati 7, ati pe ipa ti analgesic le wa ni itọju fun awọn wakati 6 ~ 8.91.4% yoo yọ kuro lati inu ito, iyokù yoo yọ kuro lati inu iyọkuro.Ni awọn alaisan ti o ni ailagbara kidirin, iye oṣuwọn pilasima lapapọ dinku ati idaji-aye gigun, nitorina iwọn lilo yẹ ki o dinku.
Ohun elo ile-iwosan: Ketorolac ni a lo ni pataki fun itọju irora igba kukuru pẹlu irora lẹhin iṣiṣẹ (gẹgẹbi ikun, àyà, Urology, gynecology, Department of Stomatology, orthopedic abẹ ati irora) bakanna bi irora iṣan eegun nla ti o fa nipasẹ ọpọlọpọ awọn idi, bii sprain, dislocation, fracture and soft tissue ipalara, ati awọn miiran irora ṣẹlẹ nipasẹ awọn arun miiran, gẹgẹ bi awọn postpartum irora, ńlá kidirin colic, toothache, sciatica, pẹ akàn irora, egbo irora, biliary colic, bbl .. O le ṣee lo. bi aropo fun morphine ati pethidine.
