L-Proline CAS 147-85-3 (H-Pro-OH) Ayẹwo 98.5 ~ 101.0% Didara Didara Factory
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti L-Proline (H-Pro-OH; Abbreviated Pro or P) (CAS: 147-85-3) pẹlu didara to gaju, agbara iṣelọpọ 2000 Tons fun ọdun kan.Gẹgẹbi ọkan ninu awọn olutaja amino acids ti o tobi julọ ni Ilu China, Kemikali Ruifu n pese awọn amino acids to awọn iṣedede agbaye, gẹgẹbi AJI, USP, EP, JP ati awọn ajohunše FCC.A le pese COA, ifijiṣẹ agbaye, kekere ati titobi pupọ ti o wa.Ti o ba nifẹ si L-Proline,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | L-Proline |
Awọn itumọ ọrọ sisọ | H-Pro-OH;L (-) - Proline;L-Pro;Abbreviated Pro tabi P;Laevo-Proline;Proline;(-) Proline;(S)-(-) Proline;(S) - Proline;(S) -Pyrrolidine-2-Carboxylic Acid;(S) -2-Pyrrolidinecarboxylic Acid;(-) -2-Pyrrolidinecarboxylic Acid;L-Pyrrolidine-2-Carboxylic Acid;L-a-Pyrrolidinecarboxylic Acid;(S) -2-Carboxypyrrolidine |
Iṣura Ipo | Ninu Iṣura, Agbara iṣelọpọ 2000 Toonu fun Ọdun |
Nọmba CAS | 147-85-3 |
Fọọmu Molecular | C5H9NO2 |
Òṣuwọn Molikula | 115.13 |
Ojuami Iyo | 228 ℃ (oṣu kejila) (tan.) |
iwuwo | 1.35 |
Ni imọlara | Hygroscopic |
Omi Solubility | Tiotuka ninu Omi, H2O: 50 mg/mL, O fẹrẹ to akoyawo |
Solubility | Tiotuka Larọwọto ni Glacial Acetic Acid, Sparing Soluble ni Ethanol.Ni iṣe Insoluble ni Eteri |
Ibi ipamọ otutu. | Ididi ni Gbẹ, Itaja ni Yara otutu |
COA & MSDS | Wa |
Iyasọtọ | Amino Acids |
Brand | Ruifu Kemikali |
Awọn koodu ewu | Xi, Xn |
Awọn Gbólóhùn Ewu | R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara. R22 - ipalara ti o ba gbe |
Awọn Gbólóhùn Aabo | S24/25 - Yago fun olubasọrọ pẹlu ara ati oju. S36/37/39 - Wọ aṣọ aabo to dara, awọn ibọwọ ati aabo oju / oju. S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun. |
WGK Germany | 3 |
RTECS | TW3584000 |
F | 3-10 |
TSCA | Bẹẹni |
HS koodu | 2933990099 |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | Awọn kirisita funfun tabi Crystalline Powder;Didun Didun Lenu | Ni ibamu |
Idanimọ | Infurarẹẹdi Absorption julọ.Oniranran | Ni ibamu |
Yiyi pato [α] 20/D | -84.5° si -86.0° (Ayẹwo gbigbe, C=4, H2O) | -85.51° |
Ipo Solusan (Gbigbepo) | Ko o ati Alailowaya ≥98.0% | 98.5% |
Kloride (Cl) | ≤0.020% | <0.020% |
Sulfate (SO4) | ≤0.020% | <0.020% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Irin (Fe) | ≤10ppm | <10ppm |
Awọn Irin Eru (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
Awọn amino acids miiran | Chromatographically Ko ṣe iwari | Ni ibamu |
Pipadanu lori Gbigbe | ≤0.30% (ni 105℃ fun wakati 3) | 0.16% |
Ajẹkù lori Iginisonu (Sulfated) | ≤0.10% | 0.07% |
Ayẹwo | 98.5 si 101.0% (Titration, gẹgẹbi ipilẹ gbigbẹ) | 99.7% |
Idanwo pH | 5.9 si 6.9 (1.0g ni 10ml ti H2O) | 6.2 |
Ninhydrin-Rere Awọn nkan | Ni ibamu | Ni ibamu |
Ipilẹṣẹ | Lati Orisun ti kii ṣe Ẹranko | Ni ibamu |
Awọn ohun elo ti o ku | Ni ibamu | Ni ibamu |
Ipari | Pade AJI97;EP;USP;Awọn pato Idanwo JP | |
Awọn Lilo akọkọ | Amino acids;Awọn afikun Ounjẹ;Awọn oogun oogun;Àfikún oúnjẹ |
L-Proline (H-Pro-OH) (CAS: 147-85-3) AJI 97 Ọna idanwo
Idanimọ: Ṣe afiwe irisi gbigba infurarẹẹdi ti ayẹwo pẹlu ti boṣewa nipasẹ ọna disiki bromide potasiomu.
Yiyi pato [α] 20/D: Ayẹwo gbígbẹ, C = 4, H2O
Ipo Solusan (Igbejade): 1.0g ni 10ml ti H2O, spectrophotometer, 430nm, 10mm cell sisanra.
Chloride (Cl): 0.7g, A-1, atunṣe: 0.40ml ti 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), atunṣe: 0.50ml ti 0.005mol/L H2SO4
Iron (Fe): 1.5g, Ref: 1.5ml of Iron Std.(0.01mg/ml)
Awọn irin Eru (Pb): 2.0g, (1), atunṣe: 2.0ml ti Pb Std.(0.01mg/ml)
Arsenic (As2O3): 2.0g, (1), atunṣe: 2.0ml ti As2O3 Std.
Awọn amino acids miiran: Ayẹwo Idanwo: 30μg, B-6-a
Pipadanu lori Gbigbe: ni 105 ℃ fun awọn wakati 3.
Ayẹwo: Ayẹwo ti o gbẹ, 120mg, (1), 3ml ti formic acid, 50ml ti glacial acetic acid, 0.1mol/L HCLO4 1ml=11.513mg C5H9NO2
Idanwo pH: 1.0g ni 10ml ti H2O
L-Proline (H-Pro-OH) (CAS: 147-85-3) Ọna idanwo USP35
ITUMO
Proline ni NLT 98.5% ati NMT 101.5% ti L-Proline (C5H9NO2), iṣiro lori ipilẹ ti o gbẹ.
Ìdámọ̀
A. INFRED ABSORPTION <197K>
ASAY
Ilana
Ayẹwo: 110 mg ti Proline
Òfo: Illa 3 milimita ti formic acid ati 50 milimita ti glacial acetic acid.
Titrimetric eto
(Wo Titrimetry <541>)
Ipo: Taara titration
Titrant: 0.1 N perchloric acid VS
Wiwa ipari: Potentiometric
Onínọmbà: Tu Ayẹwo naa sinu 3 milimita ti formic acid ati 50mL ti glacial acetic acid.Titrate pẹlu Titrant.Ṣe ipinnu òfo.
Ṣe iṣiro ipin ogorun Proline (C5H9NO2) ninu Ayẹwo ti o ya:
Esi = {[(VS-VB) x N x F]/W} x100
VS= iwọn didun Titrant jẹ nipasẹ Ayẹwo (mL)
VB= iwọn didun Titrant jẹ nipasẹ Òfo (mL)
N= deede deede ti Titrant (mEq/ml)
F= ifosiwewe deede, 115.1 mg/mEq
W= Ayẹwo iwuwo (mg)
Awọn ilana gbigba: 98.5% ~ 101.5% lori ipilẹ ti o gbẹ
ALÁÌṢẸ́
AGBEGBE LORI ININU <281>: NMT 0.4%
KOLORIDE ATI SULFATE, Kloride <221>
Ojutu boṣewa: 0.50mL ti 0.020 N hydrochloric acid
Ayẹwo: 0.73g ti Proline
Ilana gbigba: NMT 0.05%
chloride ATI sulfate, imi-ọjọ <221>
Ojutu boṣewa: 0.10mL ti 0.020 N sulfuric acid
Ayẹwo: 0.33g ti Proline
Awọn ibeere gbigba: NMT 0.03%
IRIN <241>: NMT 30ppm
Awọn irin eru, Ọna I <231>: NMT 15ppm
Awọn akopọ ti o jọmọ
Ojutu ibaamu eto: 0.4mg/mL kọọkan ti USP L-Proline RS ati USP L-Threonine RS ni 0.1 N hydrochloric acid
Ojutu boṣewa: 0.05mg/mL ti USP L-Proline RS ni 0.1 N hydrochloric acid.[AKIYESI- Ojutu yii ni ifọkansi kan ti o dọgba si 0.5% ti ti ojutu Ayẹwo.]
Ojutu ayẹwo: 10mg/mL ti Proline ni 0.1 N hydrochloric acid
Eto Chromatographic
(Wo Chromatography <621>, Kromatography Tinrin.)
Ipo: TLC
Adsorbent: 0.25-mm Layer ti chromatographic silica gel mix
Iwọn ohun elo: 5μL
Idagbasoke eto olomi: Butyl oti, glacial acetic acid, ati omi (3:1:1)
Reagent sokiri: 2 miligiramu/mL ti ninhydrin ninu adalu ọti butyl ati 2N acetic acid (95: 5)
Ibamu eto
Awọn ibeere ibamu: chromatogram ti ojutu ibaamu eto ṣe afihan awọn aaye meji ti o yapa kedere.
Onínọmbà
Awọn apẹẹrẹ: Ojutu ibaamu eto, Ojutu boṣewa, ati ojutu Ayẹwo.
Lẹhin gbigbe awo naa ni afẹfẹ, fun sokiri pẹlu reagent sokiri, ati ooru laarin 100 ° ati 105° fun iṣẹju 15.Ṣayẹwo awo naa labẹ ina funfun.
Awọn ibeere gbigba: Eyikeyi aaye keji ti ojutu Ayẹwo ko tobi tabi diẹ sii ju aaye akọkọ ti ojutu Standard.
Awọn aimọ ẹnikọọkan: NMT 0.5%
Lapapọ awọn aimọ: NMT 2.0%
Awọn idanwo pataki
Iyipo OPTICAL, Yiyi pato <781S>
Ojutu ayẹwo: 40 mg / mL ninu omi
Awọn ilana gbigba: -84.3 ° si -86.3 °
LOSSON gbigbẹ <731>: Gbẹ ayẹwo ni 105 ℃ fun wakati 3: o padanu NMT 0.4% ti iwuwo rẹ.
Awọn ibeere afikun
Iṣakojọpọ ati Ipamọ: Fipamọ sinu awọn apoti ti o ni pipade daradara.
USP ÌRÁNTÍ awọn ajohunše <11>
USP L-Proline RS
USP L-Threonine RS
Package: Igo Fluorinated, 25kg / apo, 25kg / Paali Ilu, tabi gẹgẹ bi ibeere alabara.
Ipò Ìpamọ́:Hygroscopic.Fipamọ sinu awọn apoti edidi ni itura, gbigbẹ ati ile-itaja ti afẹfẹ kuro ni awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.Ibamu pẹlu awọn aṣoju oxidizing lagbara.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
L-Proline (H-Pro-OH; Abbreviated Pro tabi P) (CAS: 147-85-3) jẹ amino acid didoju.Botilẹjẹpe proline jẹ ipin bi amino acid, o n sọrọ ni muna imino acid, niwọn bi o ti ni ẹgbẹ imino kan (isopọ carbon-nitrogen double bond).Nitori pq ẹgbẹ pyrrolidine cyclic rẹ o ti pin si bi amino acid aliphatic ti kii-polar.
Ohun elo
O ti wa ni lo ninu biokemika iwadi, oogun fun aito, amuaradagba aipe, arun inu, gbigbona ati postoperative amuaradagba afikun.
1. Gẹgẹbi amino acid, o le ṣe afikun awọn eroja ati pe o jẹ ohun elo aise fun idapo amino acid.
2. O munadoko fun haipatensonu ati pe o jẹ agbedemeji pataki fun iṣelọpọ ti awọn oogun antihypertensive akọkọ-ila bi captopril ati enalapril.
3. Gẹgẹbi afikun ijẹẹmu, o le mu ilọsiwaju ti awọn tissu jẹ ki o si mu oṣuwọn iwalaaye ti callus.Awọn adun pẹlu iba suga waye ifa amino-carbonyl, le ṣe ina awọn nkan adun pataki kan.China GB 2760-86 pese le ṣee lo bi turari.
4. O le ni imunadoko lati dinku ibajẹ ti aapọn iyọ si eto mitochondrial ti awọn irugbin ti o tun ṣe iresi.
5. L-Proline jẹ amino acid ti kii ṣe pataki.Peptides mnu si proline, ṣiṣe awọn ti o kan wulo ile Àkọsílẹ fun awọn ọlọjẹ.O le ṣee lo bi paati media media asa sẹẹli fun iṣelọpọ biomanufacturing ti iṣowo ti awọn ọlọjẹ isọdọkan ati awọn ọlọjẹ monoclonal.
6. L-Proline ti wa ni lilo bi asymmetric catalysts ni Organic kolaginni ati asymmetric aldol cyclization.O jẹ paati ti nṣiṣe lọwọ ti collagen ati kopa ninu iṣẹ ṣiṣe to dara ti awọn isẹpo ati awọn tendoni.O wa awọn lilo ninu oogun, awọn ohun elo imọ-ẹrọ nipa ohun-ini osmoprotectant rẹ.
Iṣẹ:
1. L-Proline ati awọn itọsẹ rẹ nigbagbogbo ni a lo bi awọn ayase asymmetric ni awọn aati Organic.Idinku CBS ati isọdi aldol ti o ni itọsi proline jẹ apẹẹrẹ pataki.
2. L-Proline jẹ osmoprotectant ati nitorina ni a lo ni ọpọlọpọ awọn oogun, awọn ohun elo imọ-ẹrọ.Ninu pipọnti, awọn ọlọjẹ ọlọrọ ni proline darapọ pẹlu awọn polyphenols lati gbe awọn haze.
3. L-Proline jẹ ọkan ninu awọn amino acids pataki fun sisọpọ amuaradagba eniyan.O jẹ lilo pupọ ni ounjẹ ati ile-iṣẹ iṣoogun, ati pe o jẹ agbedemeji pataki fun sisọpọ awọn inhibitors ACE bii Captopril ati Enalapril.O tun jẹ ọkan ninu awọn ohun elo aise pataki ti gbigbe ẹjẹ amino acid.
4. L-Proline ti lo ni gbogbo agbaye bi afikun ounjẹ, ayase ati awọn ohun elo aise ti ile-iṣẹ kemikali daradara.