L-Serine CAS 56-45-1 (H-Ser-OH) Ayẹwo 98.5 ~ 101.0% Didara Didara Factory
Shanghai Ruifu Kemikali Co., Ltd jẹ olutaja asiwaju ti L-Serine (H-Ser-OH; Abbreviated Ser or S) (CAS: 56-45-1) pẹlu didara to gaju.Gẹgẹbi ọkan ninu awọn olupese amino acids ti o tobi julọ ni Ilu China, Ruifu Kemikali n pese awọn amino acids pade AJI, USP, EP, JP ati awọn ajohunše FCC.A le pese COA, ifijiṣẹ agbaye, kekere ati titobi pupọ ti o wa.Ti o ba nifẹ si L-Serine,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | L-Serine |
Awọn itumọ ọrọ sisọ | H-Ser-OH;L-Ser;Abbreviated Ser tabi S;(-) Serine;Serine;Laevo-Serine;(S)-Serine;L-2-Amino-3-Hydroxypropionic Acid;(S) -2-Amino-3-Hydroxypropionic Acid;(S) -α-Amino-β-Hydroxypropionic Acid;L-3-Hydroxy-2-Aminopropionic Acid;3-Hydroxy-L-Alanine;β-Hydroxy-L-Alanine |
Iṣura Ipo | Ninu Iṣura, Agbara iṣelọpọ 500 Toonu fun Ọdun |
Nọmba CAS | 56-45-1 |
Fọọmu Molecular | C3H7NO3 |
Òṣuwọn Molikula | 105.09 |
Ojuami Iyo | 222 ℃ (oṣu kejila) (tan.) |
iwuwo | 1.6 |
Omi Solubility | Tiotuka ninu Omi, Fere akoyawo |
Solubility | Soluble Larọwọto ni Formic Acid.Ni iṣe Insoluble ni Ethanol ati ni Eteri.Tituka ni Dilute Hydrochloric Acid |
Ibi ipamọ otutu. | Ididi ni Gbẹ, Itaja ni Yara otutu |
COA & MSDS | Wa |
Iyasọtọ | Amino Acids & Awọn itọsẹ |
Brand | Ruifu Kemikali |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | Awọn kirisita funfun tabi Crystalline Powder | Ni ibamu |
Idanimọ | Infurarẹẹdi Absorption julọ.Oniranran | Ni ibamu |
Yiyi pato [α] 20/D | +14.4° si +15.5° (C=10, 2N HCl) | -33.8° |
Ipo Solusan (Gbigbepo) | Ko o ati Alailowaya ≥98.0% | 98.6% |
Kloride (Cl) | ≤0.020% | <0.020% |
Sulfate (SO4) | ≤0.020% | <0.020% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Irin (Fe) | ≤10ppm | <10ppm |
Awọn Irin Eru (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
Awọn amino acids miiran | Chromatographically Ko ṣe iwari | Ni ibamu |
Pipadanu lori Gbigbe | ≤0.20% (ni 105℃, 3 wakati) | 0.15% |
Ajẹkù lori Iginisonu (Sulfated) | ≤0.10% | 0.06% |
Ayẹwo | 98.5 si 101.0% (Titration: ipilẹ gbigbe) | 99.7% |
Idanwo pH | 5.2 si 6.2 (1.0g ni 10ml ti H2O) | 5.5 |
Organic Iyipada impurities | Pade Awọn ibeere | Ni ibamu |
Ipilẹṣẹ | Orisun ti kii-Eranko | Ni ibamu |
Awọn ohun elo ti o ku | Ni ibamu | Ni ibamu |
Ipari | Pade AJI97, EP, USP, JP Awọn pato Idanwo | |
Igbesi aye selifu | Awọn oṣu 24 Lati Ọjọ iṣelọpọ ti o ba wa ni ipamọ daradara | |
Awọn Lilo akọkọ | Awọn afikun Ounjẹ;Awọn oogun oogun;Afikun Ounjẹ;ati be be lo. |
Package: Igo Fluorinated, 25kg / apo, 25kg / Paali Ilu, tabi gẹgẹ bi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti edidi ni itura, gbigbẹ ati ile-itaja ti afẹfẹ kuro ni awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
JP16
L-Serine, nigba ti o gbẹ, ko kere ju 98.5% ko si ju 101.0% ti C3H7NO3 lọ.
Apejuwe L-Serine waye bi awọn kirisita funfun tabi lulú kirisita kan.O ni itọwo didùn diẹ.O jẹ tiotuka larọwọto ninu omi ati ni formic acid, ati ni iṣe insoluble ni ethanol (99.5).O tuka ni 2 mol/L hydrochloric acid TS.
Idanimọ Ṣe ipinnu iyasọtọ gbigba infurarẹẹdi ti L-Serine gẹgẹbi itọsọna ni ọna disiki bromide potasiomu labẹ Infurarẹẹdi Spectrophotometry<2.25>, ki o si ṣe afiwe spekitiriumu pẹlu Spectrum Itọkasi: mejeeji spectra ṣe afihan awọn agbara gbigba kanna ni awọn nọmba igbi kanna.
Yiyi opitika <2.49> [a] 20D: +14.0°~+16.0°(Lẹhin gbigbe-gbẹ, 2.5 g, 2 mol/L hydrochloric acid TS, 25 mL, 100 mm).
pH <2.54> pH ti ojutu ti a pese sile nipasẹ itu 1.0 g L-Serine ni 10 milimita ti omi wa laarin 5.2 ati 6.2.
Mimo (1) Mimọ ati awọ ti ojutu-tu 1.0 g L-Serine ni omi 10 milimita: ojutu jẹ kedere ati laisi awọ.
(2) Chloride <1.03> -Ṣe idanwo naa pẹlu 0.5 g ti L-Serine.Mura ojutu iṣakoso pẹlu 0.30 milimita ti 0.01mol/L hydrochloric acid VS (kii ṣe ju 0.021%)
(3) Sulfate <1.14> Ṣe idanwo naa pẹlu 0.6 g ti L-Serine.Mura ojutu iṣakoso pẹlu 0.35 milimita ti 0.005mol/L sulfuric acid VS (kii ṣe ju 0.028%).
(4) Ammonium <1.02> -Ṣe idanwo naa pẹlu 0.25 g ti L-Serine.Mura ojutu iṣakoso pẹlu 5.0 milimita ti Solusan Ammonium Standard (kii ṣe ju 0.02%).
(5) Awọn irin Heavy <1.07> Tẹsiwaju pẹlu 2.0 g ti L-Serine ni ibamu si Ọna 1, ati ṣe idanwo naa.Mura ojutu iṣakoso pẹlu 2.0 milimita ti Solusan Lead Standard (kii ṣe ju 10 ppm).
(6) Iron <1.10> Mura ojutu idanwo pẹlu 1.0 g ti L-Serine gẹgẹbi Ọna 1, ki o si ṣe idanwo naa ni ibamu si Ọna A. Mura ojutu iṣakoso pẹlu 1.0mL ti Standard Iron Solution (kii ṣe ju 10 ppm) .
(7) Awọn nkan ti o jọmọ-tu 0.10 g L-Serine ni omi 10mL, ati lo ojutu yii bi ojutu ayẹwo.Pipet 1 milimita ti ojutu ayẹwo, ṣafikun omi lati ṣe deede 10 milimita.Pipet 1 milimita ti ojutu yii, fi omi kun si 50 milimita gangan, ati lo ojutu yii bi ojutu boṣewa.Aami 5mLeachofthesamplesolution ati ojutu boṣewa lori awo ti silica gel forthin-Layer chromatography.Lẹhinna dagbasoke pẹlu adalu 1-butanol, omi ati acetic acid (100) (3: 1: 1) si ijinna to bii 10 cm, ki o si gbẹ awo ni 809C fun ọgbọn išẹju 30.Sokiri ojutu kan ti ninhydrinin adalu methanol andacetic acid (100) (97: 3) (1 ni 100) lori awo, ati ooru ni 80℃ fun iṣẹju mẹwa 10: aaye miiran yatọ si aaye akọkọ ti a gba lati ojutu ayẹwo kii ṣe diẹ intense thanthe iranran lati boṣewa ojutu.
Pipadanu lori Gbigbe <2.41> Ko si ju 0.3% (1 g, 105 ℃, wakati 3).
Aloku lori Iginisonu <2.44> Ko ju 0.1% (1 g).
Assay Weigh deede nipa 0.11 g L-Serine, ti o gbẹ tẹlẹ, tu ni 3 mL ti formic acid, fi 50 milimita ti acetic acid (100), ati titrate <2.50> pẹlu 0.1 mol/L perchloric acid VS (titration potentiometric).Ṣe ipinnu òfo ni ọna kanna, ati ṣe atunṣe to ṣe pataki.
Kọọkan milimita ti 0.1 mol/L perchloric acid VS 10.51 mg ti C3H7NO3
Awọn apoti ati awọn apoti ipamọ-Awọn apoti ti o nipọn.
USP39-NF34
Itumọ L-Serine ni NLT 98.5% ati NMT 101.5% ti L-serine (C3H7NO3), ṣe iṣiro lori ipilẹ ti o gbẹ.
Ìdámọ̀
A. INFRED ABSORPTION <197K>
ASAY
Ilana
Ayẹwo: 100mg ti Serine
Òfo: Illa 3mL ti formic acid ati 50mL ti glacial acetic acid.
Titrimetric eto
(Wo Titrimetry <541>)
Ipo: Taara titration
Titrant: 0.1 N perchloric acid VS
Wiwa ipari: Potentiometric
Onínọmbà: Tu Ayẹwo naa sinu 3mL ti formic acid ati 50mL ti glacial acetic acid.Titrate pẹlu Titrant.
Ṣe ipinnu òfo.
Ṣe iṣiro ipin ti serine (C3H7NO3) ninu ayẹwo ti o ya:
Esi = {[(VS-VB) xNxF]/W} x100
VS= Iwọn titrant jẹ nipasẹ Ayẹwo (mL)
VB= Iwọn didun titrant jẹ nipasẹ Ofo (mL)
N= deede deede ti Titrant (mEq/ml)
F = ifosiwewe deede, 105.1mg/mEq
W= Ayẹwo iwuwo (mg)
Awọn ilana gbigba: 98.5% ~ 101.5% lori ipilẹ ti o gbẹ
ALÁÌṢẸ́
IBINU AGBEGBE <281>: NMT 0.1%
CLORIDEAND SULFATE, Kloride <221>
Ojutu boṣewa: 0.50mL ti 0.020 N hydrochloric acid
Ayẹwo: 0.73g ti Serine
Ilana gbigba: NMT 0.05%
CLORIDEAND SULFATE, Sulfate <221>
Ojutu boṣewa: 0.10mL ti 0.020 N sulfuric acid
Ayẹwo: 0.33g ti Serine
Awọn ibeere gbigba: NMT 0.03%
IRIN <241>: NMT 30ppm
Pa awọn wọnyi rẹ:
Awọn irin eru, Ọna I <231>: NMT 15ppm (Oṣiṣẹ 1-Jan-201)
Awọn akopọ ti o jọmọ
Ojutu ibaamu eto: 0.4mg/mL kọọkan ti USP L-Serine RS ati USP L-Methionine RS ni 0.1 N hydrochloric acid
Ojutu boṣewa: 0.05mg/mL ti USP L-Serine RS ni 0.1 N hydrochloric acid.[AKIYESI-Ojutu yii ni ifọkansi kan ti o dọgba si bii 0.5% ti ti ojutu Ayẹwo.]
Ojutu ayẹwo: 10mg/mL ti Serine ni 0.1 N hydrochloric acid
Eto Chromatographic Wo Chromatography <621>, Chromatography Tinrin.)
Ipo: TLC
Adsorbent: 0.25-mm Layer ti chromatographic silica gel mix
Iwọn ohun elo: 5μL
Idagbasoke eto epo: ọti Butyl, ọti glacial acebutyl ati 2N acetic acid (95: 5)
Ibamu eto
Awọn ibeere ibamu: chromatogram ti ojutu ibaamu eto ṣe afihan awọn aaye meji ti o yapa kedere.
Onínọmbà
Awọn apẹẹrẹ: Ojutu ibaamu eto, Ojutu boṣewa, ati ojutu Ayẹwo.
Lẹhin gbigbe awo naa ni afẹfẹ, fun sokiri pẹlu reagent sokiri, ati ooru laarin 100 ° ati 105° fun iṣẹju 15.Ṣayẹwo awo naa labẹ ina funfun.
Awọn ibeere gbigba: Eyikeyi aaye keji ti ojutu Ayẹwo ko tobi tabi diẹ sii ju aaye akọkọ ti ojutu Standard.
Awọn aimọ ẹnikọọkan: NMT 0.5%
Lapapọ awọn aimọ: NMT 2.0%
Awọn idanwo pataki
Iyipo OPTICAL, Yiyi pato <781S>
Ojutu ayẹwo: 100mg/ml ni 2N hydrochloric acid
Awọn ilana gbigba: + 14.0 ° si + 15,6 °
LOSSON gbigbẹ <731>: Gbẹ ayẹwo ni 105 ℃ fun wakati 3: o padanu NMT 0.2% ti iwuwo rẹ.
Awọn ibeere afikun
ACKAGINGAND Ibi ipamọ: Fipamọ sinu awọn apoti ti o ni pipade daradara.
USP ÌRÁNTÍ awọn ajohunše <11>
USP L-Methionine RS
USP L-Serine RS
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Awọn aami ewu | Xi - Irritant |
Awọn koodu ewu | 36/37/38 - Irritating si oju, eto atẹgun ati awọ ara. |
Apejuwe Abo | S24/25 - Yago fun olubasọrọ pẹlu ara ati oju. S36 - Wọ aṣọ aabo to dara. S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun. |
WGK Germany | 3 |
RTECS | VT8100000 |
F | 3 |
TSCA | Bẹẹni |
HS koodu | 2922509099 |
L-Serine (H-Ser-OH; Abbreviated Ser or S) (CAS: 56-45-1) jẹ amino acid, o jẹ ọkan ninu awọn amino acids proteinogenic.Awọn codons rẹ ninu koodu jiini jẹ UCU, UCC, UCA, UCG, AGU ati AGC.Nipa agbara ti ẹgbẹ hydroxyl, serine jẹ ipin bi amino acid pola kan.
Iṣẹ ati Ohun elo ti L-Serine Cas 56-45-1
1. L-Serine ni a lo bi reagent biokemika ati awọn afikun ounjẹ;Ti a lo ninu iwadii biokemika, igbaradi alabọde aṣa agbari, oogun ti a lo fun awọn amino acids lori oogun ijẹẹmu.
2. L-Serine ni a lo ni aaye oogun, L-Serine ti wa ni lilo pupọ lati tunto idapọ amino acid kẹta ati awọn ohun elo ijẹẹmu, ati fun iṣelọpọ ti ọpọlọpọ awọn itọsẹ amino acid siliki, gẹgẹ bi ẹjẹ ọkan, akàn, AIDS ati jiini. imọ-ẹrọ ti awọn oogun tuntun ati awọn amino acids aabo miiran.Ounjẹ ati aaye mimu, L-Serine le ṣee lo si awọn ohun mimu ere idaraya, awọn ohun mimu ounjẹ ounjẹ amino acids.Aaye ifunni, L-Serine le ṣee lo si ifunni ẹran, ṣe igbelaruge idagbasoke ati idagbasoke ẹranko;
3. L-Serine ni a lo bi afikun Ounjẹ, ni awọn ohun ikunra bi afikun ounjẹ awọ ara.
4. Wa fun biokemika ati onje iwadi ìdí, sugbon tun le ṣee lo bi sintetiki oruka serine aise ohun elo.
5. L-Serine ni ọpọlọpọ awọn lilo ninu oogun.Serine ṣe igbelaruge iṣelọpọ ti awọn ọra ati awọn acids fatty ati iranlọwọ lati ṣetọju eto ajẹsara.
6. L-Serine tun lo bi afikun ounjẹ ti o jẹun ni ibi ti o le ṣe iranlọwọ fun iṣẹ iranti ti o dara si ati ni awọn ọja itọju ti ara ẹni nibiti o ṣe iranlọwọ pẹlu iṣelọpọ awọn awọ ara tuntun.
7. L-Serine ti lo ni igbaradi ti Tris-BSAN buffer fun homogenization.O tun ti lo fun itupalẹ pipo ti excretion ti polypeptides ninu ito deede.
8. L-Serine ni a lo ninu iṣelọpọ ti awọn purines ati awọn pyrimidine gẹgẹbi awọn aṣoju antibacterial / antifungal, bakannaa ti o ṣe bi eroja proteinogenic.
9. L-Serine jẹ ipin bi amino acid ti ko ṣe pataki.O ti wa ni lilo bi paati media asa sẹẹli ati ohun elo aise fun biomanufacture ti iṣowo ti awọn ọlọjẹ isọdọkan ati awọn ọlọjẹ monoclonal.
10. L-Serine nipasẹ phosphorylation-hydroxy itọsẹ le ti wa ni ti oniṣowo lẹhin ti awọn pataki physiological awọn iṣẹ-ṣiṣe ti P serine jẹ ẹya pataki ti phospholipids;
11. L-Serine pẹlu iye pH iduroṣinṣin ti ipa ti awọn oju oju, oju oju ati ti kii ṣe irritating;
12. L-Serine jẹ ẹya pataki ti o ni itọlẹ ti ara ẹni (NMF) jẹ ọkan ninu stratum corneum lati ṣetọju ipa akọkọ ti omi, L-Serine jẹ bọtini si awọn afikun ohun ikunra to ti ni ilọsiwaju.