Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0~102.0% Aworan Ifihan Factory

Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0 ~ 102.0% Factory

Apejuwe kukuru:

Orukọ Kemikali: Lenvatinib Mesylate

CAS: 857890-39-2

Ayẹwo: 98.0 ~ 102.0%

Irisi: Funfun si Paa-White Powder tabi Awọn kirisita

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Jẹmọ Products

ọja Tags

Apejuwe:

Ipese Kemikali Ruifu Lenvatinib Mesylate Intermediates Pẹlu Iwa mimọ to gaju
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Kemikali Properties:

Orukọ Kemikali	Lenvatinib Mesylate
Awọn itumọ ọrọ sisọ	4- [3-Chloro-4-[(cyclopropylaminocarbonyl) amino] phenoxy] -7-Methoxy-6-Quinolinecarboxamide Mesylate;E 7080 Mesylate;Lenvima
Nọmba CAS	857890-39-2
NỌMBA CAT	RF-PI1975
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Fọọmu Molecular	C21H19N4O4Cl.CH4O3S
Òṣuwọn Molikula	522.96
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun si Paa-White Powder tabi kirisita
Idanimọ	Nipasẹ IR;Nipasẹ UV;Nipasẹ HPLC
Solubility	Tiotuka die-die ninu Omi, Ailesolusan Ni Ethanol
Ojuami Iyo	228.0 ~ 230.0 ℃
Akoonu Omi (KF)	<1.00%
Aloku lori Iginisonu	<0.10%
Awọn irin Heavy	<20ppm
Awọn nkan ti o jọmọ
Eyikeyi Nikan Aimọ	<0.50%
Lapapọ Awọn Aimọ	<1.00%
Aseyori / Analysis Ọna	98.0 ~ 102.0% (HPLC Ipilẹ lori Gbigbe)
Olopobobo iwuwo	0.40gm/ml ~0.60gm/ml
Igbeyewo Standard	Standard Enterprise
Lilo	API

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

FAQ:

Ohun elo:

Lenvatinib Mesylate (CAS: 857890-39-2) jẹ inhibitor oral ati olona-fojusi ti VEGFR1-3, FGFR1-4, PDGFR, KIT, ati RET, pẹlu awọn iṣẹ antitumor ti o lagbara.Lenvatinib Mesylate jẹ oludena tyrosine kinase (RTK) olugba ti o ni yiyan fun VEGFR2.O ṣe afihan iṣẹ-ṣiṣe antineoplastic, ati pe o ti ni itọkasi fun itọju awọn alaisan ti o ni atunṣe ti agbegbe tabi metastatic, ilọsiwaju, iodine radioactive (RAI) -refractory differentiated tairodu akàn.Lenvatinib Mesylate ni akọkọ fọwọsi nipasẹ Ile-iṣẹ Ounje ati Oògùn AMẸRIKA (FDA) ni Oṣu kejila ọjọ 13, ọdun 2015, lẹhinna fọwọsi nipasẹ Ile-iṣẹ elegbogi ati Awọn Ẹrọ Iṣoogun ti Japan (PMDA) ni Oṣu Kẹta Ọjọ 26, Ọdun 2015, ati fọwọsi nipasẹ Ile-iṣẹ Oogun Yuroopu (EMA) lori Oṣu Karun ọjọ 28, Ọdun 2015. O jẹ idagbasoke ati tita bi Lenvima® nipasẹ Eisai.Lenvatinib Mesylate jẹ inhibitor ọpọ olugba tyrosine kinase ti oral pẹlu ipo abuda alailẹgbẹ kan ti o yan ni idinamọ awọn iṣẹ ṣiṣe kinase ti awọn olugba idagba endothelial ti iṣan (VEGF), ni afikun si awọn proangiogenic miiran ati awọn ọna oncogenic ti o ni ibatan tyrosine kinases ro pe o ni ipa ninu isunmọ tumo. .O ti wa ni itọkasi fun awọn itọju ti ilọsiwaju radioiodine-refractory differentiated tairodu akàn.Lenvimani a lo funrararẹ lati ṣe itọju akàn tairodu ti o yatọ (DTC), iru akàn tairodu ti ko le ṣe itọju pẹlu iodine ipanilara ati ti nlọsiwaju.LENVIMA ni a lo pẹlu oogun miiran ti a npe ni everolimus lati tọju awọn agbalagba ti o ni iru akàn kidinrin kan ti a npe ni carcinoma kidirin ti ilọsiwaju (RCC) lẹhin itọju kan pẹlu oogun egboogi-akàn miiran.