Linagliptin CAS 668270-12-0 Mimọ ≥99.0% (HPLC) Ile-iṣẹ
Ipese Olupese, Iwa-mimọ giga, Iṣelọpọ Iṣowo
Orukọ Kemikali: Linagliptin
CAS: 668270-12-0
Orukọ Kemikali | Linagliptin |
Awọn itumọ ọrọ sisọ | BI-1356;8-[(3R) -3-Amino-1-piperidinyl] -7- (2-butynyl) -3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H -purine-2,6-dione |
Nọmba CAS | 668270-12-0 |
NỌMBA CAT | RF-API105 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C25H28N8O2 |
Òṣuwọn Molikula | 472.54 |
Ojuami Iyo | 197.0 si 200.0 ℃ |
Solubility | Tiotuka ni DMSO |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun tabi Pa-White Crystalline Powder |
NMR | Ni ibamu Pẹlu Be |
Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
Pipadanu lori Gbigbe | ≤0.50% |
Aloku lori Iginisonu | ≤0.10% |
Awọn irin Heavy | ≤10ppm |
Awọn nkan ti o jọmọ | |
Aimọ Kanṣoṣo | ≤0.50% |
Lapapọ Awọn Aimọ | ≤1.0% |
Isomer | ≤0.15% |
Awọn ohun elo ti o ku | |
kẹmika kẹmika | ≤3000ppm |
Isopropanol | ≤5000ppm |
DMF | ≤800ppm |
Dichloromethane | ≤600ppm |
Igbeyewo Standard | Standard Enterprise |
Lilo | API |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
Linagliptin (CAS: 668270-12-0) jẹ inhibitor DPP-4 ti o dagbasoke nipasẹ Boehringer Ingelheim fun itọju iru àtọgbẹ II.Awọn abuda elegbogi meji ti o ṣeto linagliptin yato si awọn inhibitors DPP-4 miiran ni pe o ni profaili elegbogi ti kii ṣe laini ati pe ko ni imukuro nipataki nipasẹ eto kidirin.Linagliptin (ẹẹkan lojoojumọ) jẹ ifọwọsi nipasẹ US FDA ni ọjọ 2 Oṣu Karun ọdun 2011 fun itọju iru àtọgbẹ II.Boehringer Ingelheim ati Lilly n ta ọja rẹ.Linagliptin, ti a ta labẹ orukọ iyasọtọ Tradjenta laarin awọn miiran.O ti wa ni lilo pọ pẹlu idaraya ati onje.