Linezolid CAS 165800-03-3 Assay 98.0 ~ 102.0%
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti Linezolid (CAS: 165800-03-3) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra Linezolid (CAS: 165800-03-3),Please contact: alvin@ruifuchem.com
Linezolid | CAS 165800-03-3 |
3-Fluoro-4-Morpholinoaniline | CAS 93246-53-8 |
(S) -N- [2- (Acetyloxy) -3-Chloropropyl] acetamide | CAS 183905-31-9 |
(R)-[3- (3-Fluoro-4-Morpholinophenyl)-2-Oxo-5-Oxazolidinyl]methyl Methanesulfonate. | CAS 174649-09-3 |
Phthalimide Potasiomu Iyọ | CAS 1074-82-4 |
Orukọ Kemikali | Linezolid |
Awọn itumọ ọrọ sisọ | (S) -N-[[3- (3-Fluoro-4-Morpholinophenyl) -2-Oxooxazolidin-5-yl] methyl] acetamide;N-[[(5S) -3- [3-Fluoro-4- (4-Morpholinyl) phenyl] -2-Oxo-5-Oxazolidinyl]methyl] -Acetamide;N-[[(5S) -3- (3-Fluoro-4-Morpholin-4-ylphenyl) -2-Oxo-1,3-Oxazolidin-5-yl]methyl] acetamide;Linospan;Linox;PNU 100766;U 100766;Zyvox;Zyvoxid |
Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
Nọmba CAS | 165800-03-3 |
Fọọmu Molecular | C16H20FN3O4 |
Òṣuwọn Molikula | 337,35 g / mol |
Ojuami Iyo | 177.0 si 181.0 ℃ |
iwuwo | 1.302 ± 0,06 g / cm3 |
Ni imọlara | Afẹfẹ Ifamọ |
Omi Solubility | Ailopin ninu Omi, 610 mg/l 25℃ |
Solubility | Die-die Soluble ni Dichloromethane;Insoluble ni Ethanol |
COA & MSDS | Wa |
Ipilẹṣẹ | Shanghai, China |
Brand | Ruifu Kemikali |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | Funfun lati Pa-White Crystalline Powder | Funfun Crystalline Powder |
Ayẹwo | 98.0 ~ 102.0% | 99.75% |
Yiyi pato | -9,0 ° to -14,0 ° | -11.05° |
Pipadanu lori Gbigbe | <1.00% | 0.09% |
Aloku lori Iginisonu | <0.20% | 0.07% |
Awọn nkan ti o jọmọ | ||
O pọju.Aimọ Kanṣoṣo | <0.50% | Ibamu |
Eyikeyi Aimọ Aimọ | <0.50% | Ibamu |
Lapapọ Awọn Aimọ | <1.00% | Ibamu |
Awọn irin Heavy | <20ppm | <20ppm |
Infurarẹẹdi julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
1H NMR julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
Ipari | Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun |
Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Awọn aami ewu Xn - ipalara
Awọn koodu Ewu 20/21/22 - Ipalara nipasẹ ifasimu, ni ifọwọkan pẹlu awọ ara ati ti o ba gbe wọn mì.
Apejuwe Aabo S36 - Wọ aṣọ aabo to dara.
S24/25 - Yago fun olubasọrọ pẹlu ara ati oju.
WGK Germany 3
RTECS AC2720000
HS koodu 2942000000
Linezolid (CAS: 165800-03-3) jẹ iru tuntun ti azolidinone sintetiki antibacterial oogun ti o dagbasoke ati ti iṣelọpọ nipasẹ Ile-iṣẹ Pharmacia & Upiohn (ti a gba nipasẹ Pfizer), eyiti FDA fọwọsi ni Oṣu Kẹrin Ọjọ 18, Ọdun 2000. Ọja yii jẹ oogun akọkọ ti oogun naa. fọwọsi fun itọju akoran Staphylococcus aureus-sooro methicillin ni Amẹrika ni ọdun 40.O ti ṣe atokọ ni orilẹ-ede mi ni Oṣu Kẹsan ọdun 2007 ati pe o jẹ ti iṣeduro iṣoogun ti Awọn oogun Kilasi B.
Fun itọju awọn kokoro arun Gram-positive (G +) fa awọn akoran, pẹlu bacteremia nigbakanna;pneumonia nosocomial;pneumonia ti agbegbe (nitori pe awọn kokoro arun kii ṣe kanna, pneumonia ti pin si ile-iwosan si pneumonia ti ile-iwosan ati pneumonia ti agbegbe) ati bacteremia concomitant;o le ṣee lo fun idiju ti awọ ara ati awọ ara ati awọn àkóràn àsopọ rirọ, pẹlu osteomyelitis ninu awọn àkóràn ẹsẹ dayabetik;awọ ti ko ni idiju ati awọ-ara ati awọn àkóràn asọ;o tun lo fun itọju awọn feces enterococci ti vancomycin.
Oxazolidinone aporo.Idilọwọ awọn kolaginni amuaradagba kokoro arun ṣaaju ipilẹṣẹ pq.Ṣe afihan iṣẹ ṣiṣe antibacterial ti o lagbara lodi si ọpọlọpọ awọn microbes rere-giramu-sooro oogun ni fitiro ati ni vivo.
Ilana ti iṣe jẹ idinamọ ti iṣelọpọ amuaradagba, ṣugbọn ni ipele ti o yatọ si ti awọn inhibitors synthesis protein miiran.Awọn oxazolidinones sopọ mọ 23S rRNA ti ipin ipin 50S lati ṣe idiwọ iṣelọpọ ti eka ibẹrẹ 70S iṣẹ-ṣiṣe.O ti wa ni ka lati wa ni bacteriostatic lodi si enterococci ati staphylococci sugbon bacteriocidal lodi si streptococci.Atako si oxazolidinones ni a pade ni ile-iwosan nitori iyipada ninu 23S rRNA.Eyi ni a gbagbọ pe o daru aaye abuda linezolid.Awọn microorganisms aiṣedeede Giramu jẹ sooro lainidi si linezolid nitori wiwa awọn ifasoke itujade inu ti o jẹ ki o kojọpọ ninu awọn sẹẹli.