Lopinavir CAS 192725-17-0 API Atako-HIV HIV Idaabobo Idalọwọduro COVID-19 Aworan Ifihan Mimo Giga

Lopinavir CAS 192725-17-0 API Atako-HIV HIV Idaabobo Idalọwọduro COVID-19 Mimọ Giga

Apejuwe kukuru:

Orukọ Kemikali: Lopinavir

CAS: 192725-17-0

Irisi: Funfun lati Pa Funfun Powder

Ayẹwo (HPLC): 98.0% ~ 102.0%

Yiyan Peptidomitic HIV-1 Protease Inhibitor

API Didara Giga, Iṣelọpọ Iṣowo

Inquiry: alvin@ruifuchem.com

Fi imeeli ranṣẹ si wa

Alaye ọja

Jẹmọ Products

ọja Tags

Apejuwe:

Ipese Olupese pẹlu Iwa-mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Lopinavir
CAS: 192725-17-0
Alagbara Giga, Ayanfẹ Peptidomitic HIV-1 Inhibitor Protease
Ọja Iwadi ibatan COVID-19
API Didara Giga, Iṣelọpọ Iṣowo

Kemikali Properties:

Orukọ Kemikali	Lopinavir
Awọn itumọ ọrọ sisọ	LPV;ABT-378;Kaletra
Nọmba CAS	192725-17-0
NỌMBA CAT	RF-API73
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C37H48N4O5
Òṣuwọn Molikula	628.81
Ibi ipamọ igba pipẹ	Tọju Igba pipẹ ni 2-8℃
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun to Pa-White Powder
Solubility	Tiotuka larọwọto ni kẹmika ati ni Ethanol, Soluble ni 2-Propanol
Idanimọ IR	Ifiweranṣẹ gbigba infurarẹẹdi ti ayẹwo idanwo jẹ ibamu pẹlu iwọn ti iwọn itọkasi
HPLC idanimọ	Akoko idaduro ti ayẹwo idanwo ni ibamu si ti boṣewa itọkasi
Akoonu Omi (nipasẹ KF)	≤4.0%
Specific Optical Yiyi	-22,0 ° to -26,0 °
Aloku lori Iginisonu	≤0.20%
Awọn irin Heavy	≤20ppm
Ojuami Iyo	124.0 si 127.0 ℃
Sulfated Ash	≤0.20%
Ohun elo ti o ku (Ethanol)	≤0.50%
Awọn nkan ti o jọmọ	(HPLC, Agbegbe%)
Aimọ́ 1
Àìmọ́ B (RRT=0.07)	≤0.20%
Aimọ I (RRT=1.10)	≤0.20%
Eyikeyi Iwa Aimọ	≤0.10%
Aimọ́ 2	Eyikeyi Iwa Aimọ Olukuluku ≤0.10%
Lapapọ Awọn aimọ lati Ilana 1 ati 2	≤0.70%
Lapapọ Awọn Aimọ	≤1.0%
Ayẹwo (nipasẹ HPLC)	98.0% ~ 102.0%
Igbeyewo Standard	Standard Enterprise
Lilo	Yiyan Peptidomitic HIV-1 Inhibitor Protease, Ọja Iwadi ibatan COVID-19

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Lopinavir (ABT-378) jẹ alagbara ti o ga julọ, oludanu peptidomitic ti o yan ti protease HIV-1, pẹlu Kis ti 1.3 si 3.6 pM fun iru-igi ati ọlọjẹ ọlọjẹ HIV.Lopinavir ṣiṣẹ nipa didimu idagbasoke ti HIV-1 nitorinaa dina aarun ayọkẹlẹ rẹ.Lopinavir tun jẹ inhibitor SARS-CoV 3CLpro pẹlu IC50 ti 14.2 μM.Lopinavir jẹ antiretroviral ti kilasi inhibitor protease.Idinamọ ti HIV-1 protease ṣe idilọwọ didasilẹ ti iṣaju polyprotein gbogun ati awọn abajade ni itusilẹ ti ko dagba, awọn virions ti ko ni akoran.Apakan ti itọju ailera apapọ lati tọju HIV/AIDS.Lopinavir, oludena protease HIV kẹfa ni kilasi “navir”, ni a ṣe ifilọlẹ ni ibamu pẹlu ritonavir, inhibitor protease HIV miiran ti o ta ọja tẹlẹ (Abbott, 1996);Ilana atilẹba yii ni a ṣe bi Kaletra fun lilo ni apapo pẹlu boya nucleoside tabi awọn inhibitors transscriptase ti kii-nucleoside fun itọju AIDS ni awọn agbalagba ati awọn ọmọde.Lopinavir jẹ agbo peptidomimetic kan pẹlu ipilẹ igbekalẹ ti o jọra si ti ritonavir, lori eyiti awọn ẹgbẹ ebute, paapaa valine ti a ti yipada, ti ṣafihan nipasẹ awọn ilana isọpọ peptide.Lopinavir jẹ oludaniloju ifigagbaga ti o lagbara ti HIV-I protease ti n ṣafihan agbara giga lodi si awọn iyipada sooro ritonavir.Ninu ọpọlọpọ awọn eya ẹranko, awọn iwadii elegbogi pẹlu ẹgbẹ lopinavirlritonavir fihan pe awọn ohun-ini iwọntunwọnsi ti lopinavir ni ilọsiwaju ni pataki niwaju ritonavir, ni awọn ofin ti Cmax ati iye akoko iṣe.