Luliconazole CAS 187164-19-8 Mimọ ≥99.0% HPLC Factory API Didara Giga
Ipese Luliconazole ati Awọn agbedemeji ti o jọmọ
Luliconazole CAS 187164-19-8
(1-Imidazyl) acetonitrile CAS 98873-55-3
(S) -2,4-Dichloro-α-(Chloromethyl) benzyl Ọtí CAS 126534-31-4
| Orukọ Kemikali | Luliconazole |
| Awọn itumọ ọrọ sisọ | (2E) -2- [(4R) -4- (2,4-Dichlorophenyl) -1,3-dithiolan-2-ylidene] -2- (1H-imidazol-1-yl) acetonitrile;NND 502 |
| Nọmba CAS | 187164-19-8 |
| NỌMBA CAT | RF-API110 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C14H9Cl2N3S2 |
| Òṣuwọn Molikula | 354.27 |
| Ojuami Iyo | 150.0 si 154.0 ℃ |
| Yiyi pato [a] 20/D | -48.0° si -53.0° (C=1, DMF) |
| Solubility | Ailopin ninu Omi;Soluble ni acetone;Tiotuka die-die ni kẹmika |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Pa-White to Light Yellow Crystalline Powder |
| Idanimọ IR | Iwọn infurarẹẹdi ti ayẹwo yẹ ki o ṣe deede si ti boṣewa itọkasi |
| HPLC idanimọ | Akoko idaduro ti tente oke pataki ti ojutu ayẹwo yẹ ki o baamu ti ojutu boṣewa bi a ti gba ninu idanwo naa |
| Pipadanu lori Gbigbe | ≤0.50% |
| Aloku lori Iginisonu | ≤0.20% |
| Awọn Irin Eru (Pb) | ≤20ppm |
| Awọn nkan ti o jọmọ | |
| Eyikeyi Olukuluku aimọ | ≤0.20% |
| Lapapọ Awọn Aimọ | ≤0.50% |
| Awọn ohun elo ti o ku | |
| kẹmika kẹmika | ≤3000ppm |
| Acetonitrile | ≤410ppm |
| Dichloromethane | ≤600ppm |
| N-Hexane | ≤290ppm |
| Ethyl acetate | ≤5000ppm |
| Tetrahydrofuran | ≤720ppm |
| Methyl tert-Butyl Eteri | ≤5000ppm |
| N-Heptane | ≤5000ppm |
| Triethylamine | ≤320ppm |
| Dimethyl sulfoxide | ≤5000ppm |
| Mimọ / Analysis Ọna | ≥99.0% (HPLC) (lori ipilẹ ti o gbẹ) |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | elegbogi Intermediates |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
Luliconazole (CAS: 187164-19-8) jẹ apakokoro antifungal imidazole ti agbegbe pẹlu iwọn-nla ati iṣẹ-ṣiṣe antifungal ti o lagbara.Luliconazole jẹ iru afọwọṣe ti lanoconazole.O le dabaru pẹlu iṣelọpọ ogiri sẹẹli olu ati idagbasoke olu nipasẹ idinku awọn ipele ti ergosterol nipasẹ didaduro iṣẹ ṣiṣe lanosterol demethylase.Yato si lilo fun itọju ẹsẹ elere, jock itch ati ringworm, o tun ti ni idagbasoke fun itọju onychomycosis (nail fungus) ati pe o tun ti wọ inu ipele ile-iwosan III bayi.Ọja yii jẹ idagbasoke ni akọkọ nipasẹ Ile-iṣẹ ipakokoropaeku Japanese (NihonNohyaku Co., Ltd.).Ni Oṣu kọkanla ọdun 2013, FDA ti fọwọsi ipara luliconazole 1% kan fun titẹ si ọja fun itọju agbegbe ti ẹsẹ elere-ije interdigital, jock itch ati ringworm pẹlu orukọ iṣowo jẹ Luzu ati kọkọ wọle si ọja ni Ariwa America.Ni ibẹrẹ bi Oṣu Kẹrin ọdun 2005, luliconazole ti fọwọsi lati wọ ọja ni Japan labẹ orukọ iṣowo Lulicon.Ni January 2010 ati Okudu 2012, o ti fọwọsi fun tita ni India ati China, lẹsẹsẹ.
