Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Mimo>99.0% (HPLC) Nintedanib Esylate Intermediate Factory Aworan Ifihan

Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Mimọ>99.0% (HPLC) Nintedanib Esylate Intermediate Factory

Apejuwe kukuru:

Orukọ Kemikali: Methyl 2-Oxoindoline-6-Carboxylate

CAS: 14192-26-8

Mimọ:> 99.0% (HPLC)

Irisi: Imọlẹ Yellow si Brown Powder

Aarin ti Nintedanib Esylate (CAS: 656247-18-6) ni itọju ti akàn ẹdọfóró ti kii-kekere kekere & idiopathic pulmonary fibrosis (IPF)

Didara to gaju, iṣelọpọ Iṣowo

E-Mail: alvin@ruifuchem.com

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ọja Tags

Apejuwe:

Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) pẹlu didara to gaju, iṣelọpọ iṣowo.

Kemikali Properties:

Orukọ Kemikali	Methyl 2-Oxoindoline-6-Carboxylate
Awọn itumọ ọrọ sisọ	2-Oxoindoline-6-Carboxylic Acid Methyl Ester;Methyl Oxindole-6-Carboxylate
Nọmba CAS	14192-26-8
NỌMBA CAT	RF-PI1524
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Ilana molikula	C10H9NO3
Òṣuwọn Molikula	191.19
Ojuami Iyo	184.0 ~ 190.0 ℃
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Ina Yellow to Brown Powder
1 H NMR julọ.Oniranran	Ni ibamu Pẹlu Be
Mimọ / Analysis Ọna	> 99.0% (HPLC)
Pipadanu lori Gbigbe	<1.00%
Lapapọ Awọn Aimọ	<1.00%
Igbeyewo Standard	Standard Enterprise
Lilo	Agbedemeji ti Nintedanib Esylate (CAS: 656247-18-6)

Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) Ipa-ọna Sintetiki

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.

Awọn anfani:

FAQ:

Ohun elo:

Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) jẹ agbedemeji ti a lo lati ṣeto Nintedanib Esylate (CAS: 656247-18-6).Nintedanib Esylate jẹ alagbara, inhibitor angiokinase meteta ẹnu ti o ni idagbasoke nipasẹ Boehringer Ingelheim ti o fojusi awọn ipa ọna proangiogenic ati pro-fibrotic ti o ni ilaja nipasẹ iṣan ti iṣan endothelial idagbasoke ifosiwewe, olugba idagba ifosiwewe fibroblast ati awọn idile olugba idagbasoke ti platelet, ati Src ati Flt-3. kinases.Nintedanib Esylate ni a fọwọsi fun itọju ti idiopathic pulmonary fibrosis (IPF), ipo kan ninu eyiti awọn ẹdọforo di ilọsiwaju ni ilọsiwaju ni akoko, nipasẹ US FDA ni Oṣu Kẹwa 2014 ati nipasẹ EMA ni January 2015. FDA funni ni nintedanib esylate fast-track , ayo awotẹlẹ, orukan ọja, ati awaridii designations.O tun fọwọsi nipasẹ EMA ni Oṣu kọkanla ọdun 2014 fun itọju ti akàn ẹdọfóró sẹẹli ti kii-kekere ni apapọ pẹlu docetaxel lẹhin chemotherapy laini akọkọ.