Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8 Mimọ>98.0% (GC) Lenvatinib Mesylate Agbedemeji Factory Aworan Ifihan

Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8 Mimọ>98.0% (GC) Ile-iṣẹ Agbedemeji Lenvatinib Mesylate

Apejuwe kukuru:

Orukọ Kemikali: Methyl 4-Amino-2-Methoxybenzoate

CAS: 27492-84-8

Mimọ:> 98.0% (GC)

Irisi: Funfun si Paa-White Powder tabi Awọn kirisita

Agbedemeji ti Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

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ọja Tags

Apejuwe:

Ipese Kemikali Ruifu Lenvatinib Mesylate Intermediates Pẹlu Iwa mimọ to gaju
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Kemikali Properties:

Orukọ Kemikali	Methyl 4-Amino-2-Methoxybenzoate
Awọn itumọ ọrọ sisọ	4-Amino-2-Methoxybenzoic Acid Methyl Ester;Methyl 4-Amino-o-Anisate;4-Amino-o-Anisic Acid Methyl Ester
Nọmba CAS	27492-84-8
NỌMBA CAT	RF-PI1974
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Ilana molikula	C9H11NO3
Òṣuwọn Molikula	181.19
iwuwo	1,179 ± 0,060 g / cm3
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun si Paa-White Powder tabi kirisita
Mimọ / Analysis Ọna	> 98.0% (GC)
Mimọ / Analysis Ọna	97.5 ~ 102.5 (Titration Nonaqueous)
Ojuami Iyo	157.0 ~ 161.0 ℃
Pipadanu lori Gbigbe	<1.00%
Lapapọ Awọn Aimọ	<2.0%
Infurarẹẹdi julọ.Oniranran	Ni ibamu si Eto
Proton NMR julọ.Oniranran	Ni ibamu si Eto
Igbeyewo Standard	Standard Enterprise
Lilo	Agbedemeji ti Lenvatinib Mesylate (CAS: 857890-39-2)

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

FAQ:

Ohun elo:

Methyl 4-Amino-2-Methoxybenzoate (CAS: 27492-84-8) le ṣee lo bi agbedemeji ti Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib jẹ oogun akàn tairodu ti o ni idagbasoke nipasẹ Eisai Corporation of Japan (koodu: E7080), ti o jẹ ti oludena ti oral multi-receptor tyrosine kinase (RTK) ati pe o le ṣe idiwọ iṣẹ ṣiṣe kinase ti ifosiwewe idagbasoke endothelial ti iṣan (VEGF) Awọn olugba VEGFR1 (VEGF) FLT1), VEGFR2 (KDR), ati VEGFR3 (FLT4).Lenvatinib tun le dẹkun ilowosi ti awọn RTK miiran ni angiogenesis pathological, idagbasoke tumo, ati ilọsiwaju akàn ayafi fun awọn iṣẹ cellular deede wọn pẹlu fibroblast growth factor (FGF) awọn olugba FGFR1, 2, 3, ati 4;Olugba ifosiwewe idagbasoke ti platelet (PDGFR [alpha]), KIT, ati RET.[Awọn itọkasi]: Lenvatinib jẹ o dara fun itọju awọn alaisan ti akàn tairodu ti iṣipopada agbegbe tabi iru metastasis, iru ilọsiwaju ati ipanilara iodine-refractory differentiated type.Ni Oṣu Keji ọjọ 13, Ọdun 2015, US FDA fọwọsi oogun anticancer Lenvatinib fun itọju akàn tairodu.Lenvatinib jẹ inhibitor enzymu-pupọ-afojusun, ti o lagbara lati dena VEGFR2 ati VEGFR3 (igbasilẹ ifosiwewe idagbasoke endothelial ti iṣan).Orukọ iṣowo ti Lenvatinib jẹ Lenvima.Ni Oṣu Karun ọjọ 20, Ọdun 2015, Ile-iṣẹ Oogun Yuroopu (EMA) fọwọsi Lenvatinib fun itọju invasive, ilọsiwaju ti agbegbe tabi iyatọ metastatic (papillary, follicular, Iru Hurthle) akàn tairodu (DTC).Ninu idanwo naa, akoko iwalaaye agbedemeji fun awọn alaisan ti DTC ipanilara iodine-refractory ti a tọju pẹlu Lenvatinib jẹ oṣu 18 lakoko ti iye fun awọn alaisan ti o gba placebo jẹ oṣu 3 nikan.